(Q35163594)

6 August 2017

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title

Interferons in multiple sclerosis. A review of the evidence (English)

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6 August 2017

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H. S. Panitch

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1282865

9 September 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1282865

9 September 2022

publication date

1 December 1992

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6 August 2017

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6 August 2017

volume

44

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6 August 2017

issue

6

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6 August 2017

page(s)

946-962

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Systemic alpha-interferon therapy of multiple sclerosis

6 August 2017

cites work

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12 December 2020

Norepinephrine inhibits gamma-interferon-induced major histocompatibility class II (Ia) antigen expression on cultured astrocytes via beta-2-adrenergic signal transduction mechanisms

1 reference

12 December 2020

Electroencephalographic abnormalities in interferon encephalopathy: a preliminary report.

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12 December 2020

Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1

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12 December 2020

Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6.

1 reference

12 December 2020

Contrasting effect of alpha/beta- and gamma-interferons on expression of macrophage Ia antigens

1 reference

12 December 2020

Enhancement of monocyte class I and II histocompatibility antigen expression in man by in vivo beta-interferon.

1 reference

12 December 2020

Preferential T-cell receptor beta-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis

1 reference

12 December 2020

Recombinant interferon-gamma increases HLA-DR synthesis and expression

1 reference

12 December 2020

Rat ependyma and microglia cells express class II MHC antigens after intravenous infusion of recombinant gamma interferon

1 reference

12 December 2020

AIDS and Kaposi's sarcoma: interferons in pathogenesis and treatment

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12 December 2020

Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis

1 reference

12 December 2020

Multicentre double-blind study of effect of intrathecally administered natural human fibroblast interferon on exacerbations of multiple sclerosis

1 reference

12 December 2020

Proteinases in inflammatory demyelinating disease

1 reference

12 December 2020

Induction and regulation of class II major histocompatibility complex mRNA expression in astrocytes by interferon-gamma and tumor necrosis factor-alpha

1 reference

12 December 2020

Interleukin-1β decreases HLA class II expression on a glioblastoma multiforme cell line

1 reference

12 December 2020

Cloned human interferon-gamma, but not interferon-beta or -alpha, induces expression of HLA-DR determinants by fetal monocytes and myeloid leukemic cell lines

1 reference

12 December 2020

Interferon production by cultured peripheral leucocytes of MS patients

1 reference

12 December 2020

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation

1 reference

12 December 2020

Virus interference. I. The interferon

1 reference

12 December 2020

The role of interferon-gamma in the pathogenesis of experimental autoimmune disease of the peripheral nervous system

1 reference

12 December 2020

MS: a CNS and systemic autoimmune disease

1 reference

12 December 2020

Limited heterogeneity of rearranged T-cell receptor V alpha transcripts in brains of multiple sclerosis patients

1 reference

12 December 2020

Cytotoxic activity and interferon production by lymphocytes from patients with multiple sclerosis

1 reference

12 December 2020

Natural killer cell activity in multiple sclerosis patients treated with recombinant interferon-alpha 2

1 reference

12 December 2020

Systemic recombinant alpha-2 interferon therapy in relapsing multiple sclerosis

1 reference

12 December 2020

Interferon Crosses Blood-Cerebrospinal Fluid Barrier in Monkeys

1 reference

12 December 2020

In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis

1 reference

12 December 2020

The natural history of multiple sclerosis: a geographically based study. 2. Predictive value of the early clinical course

1 reference

12 December 2020

Microglia are the major cell type expressing MHC class II in human white matter

1 reference

12 December 2020

Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules

1 reference

12 December 2020

Suppressor T cell activation by human leukocyte interferon

1 reference

12 December 2020

Double blind study of intrathecal beta-interferon in multiple sclerosis: clinical and laboratory results

1 reference

12 December 2020

The Purification and Manufacture of Human Interferons / Sidney Pestka. - (1983)

1 reference

12 December 2020

Interferons 1992. How much of the promise has been realised?

1 reference

12 December 2020

Interaction between myelin basic protein-sensitized T lymphocytes and murine cerebral vascular endothelial cells.

1 reference

12 December 2020

Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats

1 reference

12 December 2020

Major differences in the dynamics of primary and secondary progressive multiple sclerosis

1 reference

12 December 2020

Antagonistic effect of interferon-beta on the interferon-gamma-induced expression of Ia antigen in murine macrophages

1 reference

12 December 2020

Lymphocyte migration into brain modelled in vitro: control by lymphocyte activation, cytokines, and antigen.

1 reference

12 December 2020

Induction of macrophage Ia antigen expression by rIFN-gamma and down-regulation by IFN-alpha/beta and dexamethasone are mediated by changes in steady-state levels of Ia mRNA

1 reference

12 December 2020

A synthetic peptide from myelin proteolipid protein induces experimental allergic encephalomyelitis

1 reference

12 December 2020

HLA associations in multiple sclerosis: implications for immunopathogenesis

1 reference

12 December 2020

The placebo effect during a double blind trial of recombinant alpha 2 interferon in multiple sclerosis patients: immunological and clinical findings

1 reference

12 December 2020

Suppression of murine collagen-induced arthritis with monoclonal anti-Ia antibodies and augmentation with IFN-gamma

1 reference

12 December 2020

Anti I-A antibody suppresses active encephalomyelitis: treatment model for diseases linked to IR genes

1 reference

12 December 2020

Intrathecal Interferon Reduces Exacerbations of Multiple Sclerosis

1 reference

12 December 2020

Subacute sclerosing panencephalitis: remission after treatment with intraventricular interferon

1 reference

12 December 2020

Shared human T cell receptor V beta usage to immunodominant regions of myelin basic protein

1 reference

12 December 2020

Interferon-beta specifically inhibits interferon-gamma-induced class II major histocompatibility complex gene transcription in a human astrocytoma cell line

1 reference

12 December 2020

T cells responsive to myelin basic protein in patients with multiple sclerosis

1 reference

12 December 2020

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

1 reference

12 December 2020

Intrathecally administered natural human fibroblast interferon reduces exacerbations of multiple sclerosis. Results of a multicenter, double-blind study

1 reference

12 December 2020

Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system

1 reference

12 December 2020

Interferon in experimental autoimmune encephalomyelitis (EAE): effects of exogeneous interferon on the antigen-enhanced adoptive transfer of EAE

1 reference

12 December 2020

Cortisol stimulation by recombinant interferon-alpha 2

1 reference

12 December 2020

The immunopathology of experimental allergic encephalomyelitis. II. Endothelial cell Ia increases prior to inflammatory cell infiltration

1 reference

12 December 2020

Preliminary trial of poly ICLC in chronic progressive multiple sclerosis

1 reference

12 December 2020

Tumor necrosis factor-alpha enhances interferon-gamma-mediated class II antigen expression on astrocytes

1 reference

12 December 2020

Demonstration of alpha, beta, and gamma interferon in active chronic multiple sclerosis lesions

1 reference

12 December 2020

In vitro and in vivo activation of human mononuclear phagocytes by interferon-gamma. Studies with normal and AIDS monocytes.

1 reference

12 December 2020

Identification of CRG-2. An interferon-inducible mRNA predicted to encode a murine monokine

1 reference

12 December 2020

Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities

1 reference

12 December 2020

Regulation of human peripheral blood monocyte DR antigen expression in vitro by lymphokines and recombinant interferons

1 reference

12 December 2020

Decreased NK killing in patients with multiple sclerosis: an analysis on the level of the single effector cell in peripheral blood and cerebrospinal fluid in relation to the activity in the disease

1 reference

12 December 2020

Adult human glial cells can present target antigens to HLA-restricted cytotoxic T-cells

1 reference

12 December 2020

Lymphocytes from multiple sclerosis patients produce elevated levels of gamma interferon in vitro

1 reference

12 December 2020

Interferon-alpha and transfer factor in the treatment of multiple sclerosis: a double-blind, placebo-controlled trial. AUSTIMS Research Group

1 reference

12 December 2020

Large-scale Production of Human Leukocyte Interferon Containing 108 Units per ml

1 reference

12 December 2020

Central nervous system toxicity of interferon

1 reference

12 December 2020

Interferon responses of leukocytes in multiple sclerosis

1 reference

12 December 2020

Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals

1 reference

12 December 2020

Gamma-interferon induction in patients with chronic progressive MS

1 reference

12 December 2020

Tumor necrosis factor identified in multiple sclerosis brain

1 reference

12 December 2020

Regulation of class II major histocompatibility complex genes: relation to multiple sclerosis

1 reference

12 December 2020

Exacerbations of multiple sclerosis in patients treated with gamma interferon

1 reference

12 December 2020

Multiple sclerosis: capping of surface immunoglobulin G on macrophages engaged in myelin breakdown

1 reference

12 December 2020

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma

1 reference

12 December 2020

CD4+ suppressor cells differentially affect the production of IFN-gamma by effector cells of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Systemic lymphoblastoid interferon therapy in chronic progressive multiple sclerosis. II. Immunologic evaluation

1 reference

12 December 2020

CSF and serum interferon in multiple sclerosis: Longitudinal study

1 reference

12 December 2020

Tumor necrosis factor in serum and cerebrospinal fluid of patients with multiple sclerosis

1 reference

12 December 2020

Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells

1 reference

12 December 2020

Reduction of immunoglobulin G secretion in vitro following long term lymphoblastoid interferon (Wellferon) treatment in multiple sclerosis patients

1 reference

12 December 2020

Heterogeneity of blood-brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement.

1 reference

12 December 2020

Clinical viral infections and multiple sclerosis.

1 reference

12 December 2020

Suppression of experimental allergic encephalomyelitis by interferon

1 reference

12 December 2020

Serial immunological studies in multiple sclerosis patients treated systemically with human alpha interferon

1 reference

12 December 2020

Systemic lymphoblastoid interferon therapy in chronic progressive multiple sclerosis. I. Clinical and MRI evaluation.

1 reference

12 December 2020

Multiple sclerosis: involvement of interferons in lesion pathogenesis

1 reference

12 December 2020

In vivo and in vitro activation of alveolar macrophages by recombinant interferon-gamma

1 reference

12 December 2020

Elevated serum interleukin-2 levels in chronic progressive multiple sclerosis

1 reference

12 December 2020

Does a retrovirally encoded superantigen cause multiple sclerosis?

1 reference

12 December 2020

Multiple sclerosis (first of two parts).

1 reference

12 December 2020

Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis

1 reference

12 December 2020

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

1 reference

12 December 2020

Serial gadolinium-enhanced magnetic resonance imaging scans in patients with early, relapsing-remitting multiple sclerosis: Implications for clinical trials and natural history

1 reference

12 December 2020

Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes

1 reference

12 December 2020

Multiple sclerosis and viruses: An overview

1 reference

12 December 2020

Cortisol induction by poly ICLC: implications for clinical trials of interferon

1 reference

12 December 2020

Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)

1 reference

12 December 2020

Enhancement of suppressor T cell activity by injection of anti-IFN-gamma monoclonal antibody

1 reference

12 December 2020

Multiple sclerosis disease activity correlates with gadolinium-enhanced magnetic resonance imaging

1 reference

12 December 2020

Persistent neurotoxicity of systemically administered interferon-alpha.

1 reference

12 December 2020

Restricted T-cell receptor V beta gene usage by myelin basic protein-specific T-cell clones in multiple sclerosis: predominant genes vary in individuals

1 reference

12 December 2020

Peripheral blood ?-? T cells lyse fresh human brain?Derived oligodendrocytes

1 reference

12 December 2020

Interferon beta augments suppressor cell function in multiple sclerosis

1 reference

12 December 2020

Interferon production and natural killer (NK) activity in leukocyte cultures from multiple sclerosis patients

1 reference

12 December 2020

Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology

1 reference

12 December 2020

Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: do cytokines trigger off exacerbations?

1 reference

12 December 2020

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

1 reference

12 December 2020

Phenotypic and functional characteristics of active suppressor cells against IFN-gamma production in PHA-stimulated cord blood lymphocytes

1 reference

12 December 2020

Major histocompatibility complex-expressing nonhematopoietic astroglial cells prime only CD8+ T lymphocytes: astroglial cells as perpetuators but not initiators of CD4+ T cell responses in the central nervous system

1 reference

12 December 2020

Distribution of alpha interferon in serum and cerebrospinal fluid after systemic administration.

1 reference

12 December 2020

A neurologic rating scale (NRS) for use in multiple sclerosis

1 reference

12 December 2020

Immunology of multiple sclerosis

1 reference

12 December 2020

Down-regulation of interferon-gamma-induced class II expression on human glioma cells by recombinant interferon-beta: effects of dosage treatment schedule

1 reference

12 December 2020

Activation of a suppressor T-cell pathway by interferon

1 reference

12 December 2020

Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1

1 reference

12 December 2020

Redefining interferon: the interferon-like antiviral effects of certain cytokines (interleukin-1, interferon-beta 2, interferon-gamma) may be indirect or side effects

1 reference

12 December 2020

Activated suppressor cell dysfunction in progressive multiple sclerosis

1 reference

12 December 2020

Anti?tumor necrosis factor therapy abrogates autoimmune demyelination

1 reference

12 December 2020

Immunological complications in multiple sclerosis patients receiving interferon

1 reference

12 December 2020

Multiple sclerosis: relevance of class I and class II MHC-expressing cells to lesion development

1 reference

12 December 2020

Heterogeneity of the T-cell receptor ? gene rearrangements generated in myelin basic protein-specific T-cell clones isolated from a patient with multiple sclerosis

1 reference

12 December 2020

In vivo activated T lymphocytes in the peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

1 reference

12 December 2020

Endogenous and interferon-augmented natural killer cell activity of human peripheral blood mononuclear cells in vitro. Studies of patients with multiple sclerosis, systemic lupus erythematosus or rheumatoid arthritis

1 reference

12 December 2020

Interferon-beta impairs induction of HLA-DR antigen expression in cultured adult human astrocytes

1 reference

12 December 2020

Natural killer cell activity in patients with multiple sclerosis given alpha interferon.

1 reference

12 December 2020

Mechanisms in multiple sclerosis

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12 December 2020

10.2165/00003495-199244060-00004

Identifiers

DOI

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Dimensions Publication ID

6 August 2017

1001861700

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