(Q35163757)

6 August 2017

Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis (English)

1 reference

6 August 2017

Rami A

1

1 reference

6 August 2017

1 July 2003

1 reference

6 August 2017

Neurobiology of Disease

1 reference

6 August 2017

13

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6 August 2017

2

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6 August 2017

75-88

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Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Induction of beta-amyloid-containing polypeptides in hippocampus: evidence for a concomitant loss of synaptic proteins and interactions with an excitotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Increased expression of IL-1beta converting enzyme in hippocampus after ischemia: selective localization in microglia

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Calpastatin is up-regulated in response to hypoxia and is a suicide substrate to calpain after neonatal cerebral hypoxia-ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"?

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Actin is cleaved during constitutive apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

p53 expression in brain after middle cerebral artery occlusion in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

1 reference

7 January 2021

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: evidence against programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

X-linked IAP is a direct inhibitor of cell-death proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Effect of calpain on the composition and structure of postsynaptic densities.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Desmin degradation and Ca(2+)-dependent proteolysis during myoblast fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

ICE, neuronal apoptosis and neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Apoptosis-associated cleavage of beta-catenin in human colon cancer and rat hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Role of troponin I proteolysis in the pathogenesis of stunned myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Brain G-protein proteolysis by calpain: enhancement by lithium.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Attenuation of TGF-beta-induced apoptosis in primary cultures of hepatocytes by calpain inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Decreased inositol (1,4,5)-trisphosphate receptor levels in Alzheimer's disease cerebral cortex: selectivity of changes and possible correlation to pathological severity.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Rapid fragmentation of vimentin in human skin fibroblasts exposed to tamoxifen: a possible involvement of caspase-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Expression of redox factor-1, p53-activated gene 608 and caspase-3 messenger RNAs following repeated unilateral common carotid artery occlusion in gerbils--relationship to delayed cell injury and secondary failure of energy state

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

The prolonged presence of glia-derived nexin, an endogenous protease inhibitor, in the hippocampus after ischemia-induced delayed neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Neuroprotection with a calpain inhibitor in a model of focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Involvement of caspase-3 in cell death after hypoxia-ischemia declines during brain maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Activation of caspase-3-like protease by digitonin-treated lysosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Degradation of microtubule-associated protein 2 and brain spectrin by calpain: a comparative study.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Altered expression of high-molecular-weight calmodulin-binding protein in human ischaemic myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Delayed neuronal death in the gerbil hippocampus following ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Activation of calpain I converts excitotoxic neuron death into a caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Inhibition of proteolysis protects hippocampal neurons from ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Apoptosis, excitotoxicity, and neuropathology

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Apoptosis after experimental stroke: fact or fashion?

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Protease activation during apoptosis: death by a thousand cuts?

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Actin cleavage by CPP-32/apopain during the development of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Evidence for synaptic apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Hippocampal Myc and p53 expression following transient global ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Evidence for participation of a calpain-like cysteine protease in cell cycle progression through late G1 phase

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Properties of calpastatin forms in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Cleavage of the cytoplasmic domain of the integrin beta3 subunit during endothelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

PEST sequences do not influence substrate susceptibility to calpain proteolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Effects of ICE-like protease and calpain inhibitors on neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Execution of apoptosis: converging or diverging pathways?

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Caspase activation as an apoptotic evidence in the gerbil hippocampal CA1 pyramidal cells following transient forebrain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Inhibition of apoptosis by the actin-regulatory protein gelsolin

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Cystatin C, a protease inhibitor, in degenerating rat hippocampal neurons following transient forebrain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Changes in calpain and calpastatin mRNA induced by beta-adrenergic stimulation of bovine skeletal muscle.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Programmed cell death and the control of cell survival: lessons from the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Neuronal protective effects of calcium antagonists in cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Calbindin-D28K and ischemic damage of pyramidal cells in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Blockade of calpain proteolytic activity rescues neurons from glutamate excitotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

mu-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Molecular evidence of apoptotic death in malignant brain tumors including glioblastoma multiforme: upregulation of calpain and caspase-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Aurintricarboxylic acid protects hippocampal neurons from NMDA- and ischemia-induced toxicity in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Implication of calpain in caspase activation during B cell clonal deletion

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Calpain: new perspectives in molecular diversity and physiological-pathological involvement.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Up- and down-regulation of calpain inhibitor polypeptide, calpastatin, in postischemic hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Oxidative stress induces neuronal death by recruiting a protease and phosphatase-gated mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Pathophysiological role of calpain in experimental demyelination

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Cell damage in the brain: a speculative synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Calpain activation in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Mechanisms and genes of cellular suicide

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

ICE-related proteases in apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

CrmA/SPI-2 Inhibition of an Endogenous ICE-related Protease Responsible for Lamin A Cleavage and Apoptotic Nuclear Fragmentation

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

m-Calpain (calcium-activated neutral proteinase) in Alzheimer's disease brains.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Protease Involvement in Fodrin Cleavage and Phosphatidylserine Exposure in Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Deoxynucleoside induces neuronal apoptosis independent of neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Calpain activation is upstream of caspases in radiation-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Transient brain ischaemia provokes Ca2+, PIP2 and calpain responses prior to delayed neuronal death in monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Proteolysis of acidic calponin by mu-calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0969-9961%2803%2900018-4

7 January 2021

10.1016/S0969-9961(03)00018-4

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12828932