(Q35164701)

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Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells.

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8 February 2020

Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells (English)

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8 February 2020

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Katrin J. Svensson

1

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8 February 2020

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8 February 2020

Mattias Belting

10

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8 February 2020

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Paulina Kucharzewska

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8 February 2020

Helena C Christianson

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8 February 2020

Stefan Sköld

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8 February 2020

Tobias Löfstedt

5

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8 February 2020

Maria C Johansson

6

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8 February 2020

Matthias Mörgelin

7

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8 February 2020

Wolfram Ruf

9

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8 February 2020

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25 July 2011

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8 February 2020

Proceedings of the National Academy of Sciences of the United States of America

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8 February 2020

108

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8 February 2020

32

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8 February 2020

13147-13152

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8 February 2020

describes a project that uses

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11 June 2022

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Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

1 reference

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Exosomes: extracellular organelles important in intercellular communication

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28 July 2018

Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells.

1 reference

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Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells

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Role of tissue factor in cancer

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Microvesicles: messengers and mediators of tumor progression

1 reference

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Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

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Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms

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Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells.

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28 July 2018

Hypoxia is important in the biology and aggression of human glial brain tumors.

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Exploiting tumour hypoxia in cancer treatment

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Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma

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Identifiers

10.1073/PNAS.1104261108

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8 February 2020

2011PNAS..10813147S

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1 reference

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8 February 2020

1 reference

Europe PubMed Central

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8 February 2020

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