(Q35167826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21723246%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Renal accumulation of biglycan and lipid retention accelerates diabetic nephropathy (English)

1 reference

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6 February 2020

5

1 reference

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6 February 2020

author name string

Joel Thompson

1

1 reference

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6 February 2020

Patricia Wilson

2

1 reference

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6 February 2020

Katie Brandewie

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21723246%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Deepa Taneja

4

1 reference

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6 February 2020

Bonnie Mitchell

6

1 reference

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6 February 2020

Lisa R Tannock

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21723246%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

language of work or name

English

0 references

publication date

30 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21723246%20AND%20SRC:MED&resulttype=core&format=json

The American Journal of Pathology

6 February 2020

published in

1 reference

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6 February 2020

volume

179

1 reference

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6 February 2020

issue

3

1 reference

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6 February 2020

page(s)

1179-1187

1 reference

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describes a project that uses

6 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3157166/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Reversibility of renal injury with cholesterol lowering in hyperlipidemic diabetic mice

1 reference

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Mouse models of diabetic nephropathy

13 July 2018

1 reference

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Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors

13 July 2018

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Rosuvastatin and cardiovascular events in patients undergoing hemodialysis

13 July 2018

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Proteoglycan mediated lipoprotein retention: a mechanism of diabetic atherosclerosis

13 July 2018

1 reference

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SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance

13 July 2018

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Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications

13 July 2018

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Decorin deficiency enhances progressive nephropathy in diabetic mice.

13 July 2018

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Podocyte proteoglycan synthesis is involved in the development of nephrotic syndrome

13 July 2018

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Impact of genetic background on nephropathy in diabetic mice

13 July 2018

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Primary human glomerular endothelial cells produce proteoglycans, and puromycin affects their posttranslational modification

13 July 2018

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Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions

13 July 2018

1 reference

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Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Cellular lipid metabolism and the role of lipids in progressive renal disease

13 July 2018

1 reference

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Elevated levels of beta defensin-1 mRNA in diabetic kidneys of GK rats.

13 July 2018

1 reference

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Biglycan, a Nitric Oxide-regulated Gene, Affects Adhesion, Growth, and Survival of Mesangial Cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Regulation of biglycan gene expression by transforming growth factor-beta requires MKK6-p38 mitogen-activated protein Kinase signaling downstream of Smad signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).

13 July 2018

1 reference

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MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

13 July 2018

1 reference

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Low density lipoproteins and mitogenic signal transduction processes: role in the pathogenesis of renal disease

13 July 2018

1 reference

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Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Mouse models of hyperlipidemia and atherosclerosis

13 July 2018

1 reference

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Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

13 July 2018

1 reference

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Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-ric

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels

13 July 2018

1 reference

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The extracellular matrix in diabetic nephropathy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Interactions between lipoproteins, glomerular cells and matrix.

13 July 2018

1 reference

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Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta

13 July 2018

1 reference

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The response-to-retention hypothesis of early atherogenesis

13 July 2018

1 reference

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Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

13 July 2018

The glomerular mesangium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Transforming growth factor-beta regulates production of proteoglycans by mesangial cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Negative regulation of transforming growth factor-beta by the proteoglycan decorin

13 July 2018

1 reference

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Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

13 July 2018

1 reference

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Angiotensin II increases vascular proteoglycan content preceding and contributing to atherosclerosis development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Regulation of vascular proteoglycan synthesis by metabolic factors associated with diabetes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Proteoglycans can mediate renal lipoprotein retention

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Characterization of susceptibility of inbred mouse strains to diabetic nephropathy.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Can murine diabetic nephropathy be separated from superimposed acute renal failure?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Foam cells generated by a combination of hyperglycemia and hyperlipemia in rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Ex vivo transfer of the decorin gene into rat glomerulus via a mesangial cell vector suppressed extracellular matrix accumulation in experimental glomerulonephritis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Hyperlipidemia aggravates renal disease in B6.ROP Os/+ mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Hyperglycemia and hyperlipidemia act synergistically to induce renal disease in LDL receptor-deficient BALB mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Amelioration of diabetic nephropathy in SPARC-null mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Proteoglycans synthesized by arterial smooth muscle cells in the presence of transforming growth factor-beta1 exhibit increased binding to LDLs

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Main risk factors for nephropathy in type 2 diabetes mellitus are plasma cholesterol levels, mean blood pressure, and hyperglycemia.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

Hyperlipidemia and kidney disease: concepts derived from histopathology and cell biology of the glomerulus

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157166

The effect of glucose on proteoglycans produced by cultured mesangial cells

27 September 2018

1 reference

12 December 2020

Expression of transforming growth factor-beta 1 during diabetic renal hypertrophy

1 reference

12 December 2020

Renal hypertrophy is associated with upregulation of TGF-beta 1 gene expression in diabetic BB rat and NOD mouse

1 reference

12 December 2020

Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice

1 reference

12 December 2020

Proteoglycans and glycosaminoglycans synthesized in vitro by mesangial cells from normal and diabetic rats

1 reference

12 December 2020

Lipoprotein abnormalities are associated with increased rate of progression of human chronic renal insufficiency

1 reference

12 December 2020

Increased decorin mRNA in diabetic mouse kidney and in mesangial and tubular cells cultured in high glucose

1 reference

12 December 2020

Renal expression of fibrotic matrix proteins and of transforming growth factor-beta (TGF-beta) isoforms in TGF-beta transgenic mice

1 reference

12 December 2020

Expression of decorin, biglycan, and collagen type I in human renal fibrosing disease

1 reference

12 December 2020

Small proteoglycans in human diabetic nephropathy: discrepancy between glomerular expression and protein accumulation of decorin, biglycan, lumican, and fibromodulin

1 reference

12 December 2020

Renal injury in apolipoprotein E-deficient mice

1 reference

12 December 2020

Interactions of low density lipoprotein with rat mesangial cells

1 reference

12 December 2020

Preferential binding of oxidized LDL to rat glomeruli in vivo and cultured mesangial cells in vitro

1 reference

12 December 2020

Intraglomerular lipid deposition in routine biopsies

1 reference

12 December 2020

Immunohistological localization of apolipoproteins in the glomeruli in renal disease: specifically apoB and apoE

1 reference

12 December 2020

Apolipoproteins and lipoprotein receptors in glomeruli in human kidney diseases

1 reference

12 December 2020

Platelet-derived growth factor and transforming growth factor-beta 1 differentially affect the synthesis of biglycan and decorin by monkey arterial smooth muscle cells

1 reference

12 December 2020

10.1016/J.AJPATH.2011.05.016

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21723246%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21723246%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference