(Q35168105)

6 August 2017

title

Identification of anti-ErbB2 dual variable domain immunoglobulin (DVD-Ig™) proteins with unique activities (English)

1 reference

6 August 2017

Jinming Gu

1

1 reference

6 August 2017

Jinsong Yang

2

1 reference

6 August 2017

Qing Chang

3

1 reference

6 August 2017

Xiaoqing Lu

4

1 reference

6 August 2017

Jieyi Wang

5

1 reference

6 August 2017

Mingjiu Chen

6

1 reference

6 August 2017

Tariq Ghayur

7

1 reference

6 August 2017

Jijie Gu

8

1 reference

6 August 2017

language of work or name

English

0 references

publication date

13 May 2014

1 reference

6 August 2017

1 reference

6 August 2017

volume

9

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6 August 2017

issue

5

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6 August 2017

page(s)

e97292

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Creative Commons Attribution 4.0 International

6 August 2017

copyright license

start time

13 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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The structure of dual-variable-domain immunoglobulin molecules alone and bound to antigen

13 July 2018

1 reference

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Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule

13 July 2018

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EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling

13 July 2018

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Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.

13 July 2018

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13 July 2018

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13 July 2018

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A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies

13 July 2018

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13 July 2018

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13 July 2018

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ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis

13 July 2018

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Lapatinib: a review of its use in the treatment of HER2-overexpressing, trastuzumab-refractory, advanced or metastatic breast cancer

13 July 2018

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13 July 2018

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Suppression of HER2/HER3-mediated growth of breast cancer cells with combinations of GDC-0941 PI3K inhibitor, trastuzumab, and pertuzumab

13 July 2018

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Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941

13 July 2018

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Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

13 July 2018

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13 July 2018

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Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

13 July 2018

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13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

ERBB receptors and cancer: the complexity of targeted inhibitors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

Overview of the trastuzumab (Herceptin) anti-HER2 monoclonal antibody clinical program in HER2-overexpressing metastatic breast cancer. Herceptin Multinational Investigator Study Group

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

The ERBB network: at last, cancer therapy meets systems biology.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

Molecular construction and optimization of anti-human IL-1alpha/beta dual variable domain immunoglobulin (DVD-Ig) molecules

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019538

Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24824849

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Design and generation of DVD-Ig™ molecules for dual-specific targeting

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24824849

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0097292

1 reference

6 August 2017

0 references

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6 August 2017

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