(Q35169682)

6 August 2017

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title

"Translocatory proteins" and "protein transduction domains": a critical analysis of their biological effects and the underlying mechanisms (English)

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6 August 2017

Jens A Leifert

1

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6 August 2017

J Lindsay Whitton

series ordinal

2

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6 August 2017

publication date

1 July 2003

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6 August 2017

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6 August 2017

volume

8

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6 August 2017

issue

1

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6 August 2017

page(s)

13-20

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Messenger proteins: homeoproteins, TAT and others

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Cell-penetrating peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Protein transduction: an alternative to genetic intervention?

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Intercellular trafficking and protein delivery by a herpesvirus structural protein

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

A new foreign policy: MHC class I molecules monitor the outside world

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Capture and processing of exogenous antigens for presentation on MHC molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Cross-presentation: a general mechanism for CTL immunity and tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

The herpes simplex virus type 1 tegument protein VP22 is encoded by gene UL49

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Phosphorylation of the herpes simplex virus type 1 tegument protein VP22.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Intercellular delivery of functional p53 by the herpesvirus protein VP22.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Cancer immunotherapy using Sindbis virus replicon particles encoding a VP22-antigen fusion.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Enhancement of sindbis virus self-replicating RNA vaccine potency by linkage of herpes simplex virus type 1 VP22 protein to antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Improving vaccine potency through intercellular spreading and enhanced MHC class I presentation of antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Enhanced immunogenicity of HPV 16 E7 fusion proteins in DNA vaccination

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Improving DNA vaccine potency by linking Marek's disease virus type 1 VP22 to an antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

A genetic immunization adjuvant system based on BVP22-antigen fusion

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

VP22-mediated intercellular transport of p53 in hepatoma cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Gene therapy by intrahepatic and intratumoral trafficking of p53-VP22 induces regression of liver tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

1 reference

7 January 2021

Homeodomain proteins in development and therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Exploring the homeobox

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Induction of protective cytotoxic T cells with viral proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Characterization of hybrid CTL epitope delivery systems consisting of the Antennapedia homeodomain peptide vector formulated in liposomes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Efficient delivery of Antennapedia homeodomain fused to CTL epitope with liposomes into dendritic cells results in the activation of CD8+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Structure-activity relationship of truncated and substituted analogues of the intracellular delivery vector Penetratin

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

A 16-mer peptide (RQIKIWFQNRRMKWKK) from antennapedia preferentially targets the Class I pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Transcription factor hoxa-5 is taken up by cells in culture and conveyed to their nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: implications for Tat-mediated pathogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Identification of a novel domain of HIV tat involved in monocyte chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

HIV-1 Tat protein mimicry of chemokines

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Monocyte-derived dendritic cells and monocytes migrate to HIV-Tat RGD and basic peptides

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

HIV-1 Tat Protein Stimulates In Vivo Vascular Permeability and Lymphomononuclear Cell Recruitment

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Immune Hyperactivation of HIV-1-Infected T Cells Mediated by Tat and the CD28 Pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Characterization of murine monoclonal antibodies to the tat protein from human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Dendritic cells transduced with protein antigens induce cytotoxic lymphocytes and elicit antitumor immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Induction of CD4(+) T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Enhancing T cell activation and antiviral protection by introducing the HIV-1 protein transduction domain into a DNA vaccine

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Protein transduction technology

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Tat-mediated delivery of heterologous proteins into cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

In vivo protein transduction: delivery of a biologically active protein into the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Transduction of full-length Tat fusion proteins directly into mammalian cells: analysis of T cell receptor activation-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

TAT-mediated protein transduction into mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Identification of a signal sequence necessary for the unconventional secretion of Engrailed homeoprotein.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Intercellular trafficking of VP22-GFP fusion proteins is not observed in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Intercellular trafficking of VP22-GFP fusion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Evaluation of VP22 spread in tissue culture

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Is VP22 nuclear homing an artifact?

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Positively charged DNA-binding proteins cause apparent cell membrane translocation

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Protein delivery using VP22.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Dual mode of signal transduction by externally added acidic fibroblast growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Stearylated arginine-rich peptides: a new class of transfection systems

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Conjugation of poly-L-lysine to albumin and horseradish peroxidase: a novel method of enhancing the cellular uptake of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

The cellular uptake of horseradish peroxidase and its poly(lysine) conjugate by cultured fibroblasts is qualitatively similar despite a 900-fold difference in rate

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Induction of specific immune responses by polycation-based vaccines

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Conformational lability of herpesvirus protein VP22.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

In vivo involvement of heparan sulfate proteoglycan in the bioavailability, internalization, and catabolism of exogenous basic fibroblast growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Role of heparan sulfate in fibroblast growth factor signalling: a structural view

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Minimal heparin/heparan sulfate sequences for binding to fibroblast growth factor-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Fibroblast growth factor-2 (FGF-2) in the nucleus: translocation process and targets

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Role of heparan sulphate proteoglycans in the regulation of human lactoferrin binding and activity in the MDA-MB-231 breast cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

Identification of an import signal for, and the nuclear localization of, human lactoferrin.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900151-5

7 January 2021

10.1016/S1525-0016(03)00151-5

Identifiers

DOI

1 reference

6 August 2017

1 reference