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Proinsulin-a pathogenic autoantigen in type 1 diabetes.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Proinsulin-a pathogenic autoantigen in type 1 diabetes
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
main subject
type-1 diabetes
0 references
author
Parth Narendran
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
author name string
Stuart I Mannering
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
Leonard C Harrison
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
publication date
1 June 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
published in
Autoimmunity Reviews
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
204-210
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
cites work
Type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New aspects of proinsulin physiology and pathophysiology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoantibodies to insulin and to proinsulin in type 1 diabetic patients and in at-risk probands differentiate only little between both antigens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proinsulin autoantibodies are more closely associated with type 1 (insulin-dependent) diabetes mellitus than insulin autoantibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin autoantibodies: more specific than proinsulin autoantibodies for prediction of type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proinsulin-specific autoantibodies are relatively infrequent in young offspring with pre-type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular immune responses against proinsulin: no evidence for enhanced reactivity in individuals with IDDM
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell response to proinsulin and insulin in type 1 and pretype 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: a study using HLA DQ8 and DQ6 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transfer of diabetes type 1 by bone-marrow transplantation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is type 1 diabetes transmissible by bone marrow allograft?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen-specific therapy for autoimmune disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell response to preproinsulin I and II in the nonobese diabetic mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-specific tolerance in diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1568-9972%2803%2900009-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1568-9972(03)00009-0
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed publication ID
12848947
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12848947
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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