(Q35172763)

6 August 2017

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title

Metabolic engineering of apoptosis in cultured animal cells: implications for the biotechnology industry (English)

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6 August 2017

0 references

1

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6 August 2017

Sandra Juanola

2

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6 August 2017

Jordi Joan Cairó

series ordinal

3

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6 August 2017

Francesc Gòdia

series ordinal

4

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6 August 2017

publication date

1 April 2003

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6 August 2017

published in

Metabolic Engineering

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6 August 2017

volume

5

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6 August 2017

issue

2

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6 August 2017

page(s)

124-132

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Apoptosis in cell culture

6 August 2017

cites work

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7 January 2021

CrmA-inhibitable cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein during Fas- and tumor necrosis factor-induced apoptosis

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7 January 2021

Bcl-XL and Bcl-2 repress a common pathway of cell death

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7 January 2021

Prolongation of murine hybridoma cell survival in stationary batch culture by Bcl-xL expression.

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7 January 2021

Protection of hybridoma cells against apoptosis by a loop domain-deficient Bcl-xL protein.

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7 January 2021

Conversion of Bcl-2 to a Bax-like death effector by caspases

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7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

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7 January 2021

Transfer of genes to humans: early lessons and obstacles to success

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7 January 2021

Endogenous inhibitors of caspases

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7 January 2021

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7 January 2021

All along the watchtower: on the regulation of apoptosis regulators.

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7 January 2021

Effect of bcl-2 expression on hybridoma cell growth in serum-supplemented, protein-free and diluted media

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7 January 2021

Influence of bcl-2 on antibody productivity in high cell density perfusion cultures of hybridoma

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7 January 2021

Comparison of Bcl-2 to a Bcl-2 deletion mutant for mammalian cells exposed to culture insults

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7 January 2021

Nucleosomes occurring in protein-free hybridoma cell culture. Evidence for programmed cell death

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7 January 2021

Reinforcing apoptosis-resistance of COS and myeloma cells by transfecting with bcl-2 gene

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7 January 2021

The impact of mammalian gene regulation concepts on functional genomic research, metabolic engineering, and advanced gene therapies

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7 January 2021

Molecular regulation of cell-cycle progression and apoptosis in mammalian cells: implications for biotechnology

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7 January 2021

Regulated overexpression of the survival factor bcl-2 in CHO cells increases viable cell density in batch culture and decreases DNA release in extended fixed-bed cultivation

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7 January 2021

Araldite as an embedding medium for electron microscopy.

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7 January 2021

Apoptosis in batch cultures of Chinese hamster ovary cells

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7 January 2021

Apoptosis in viral pathogenesis

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7 January 2021

The biochemistry of apoptosis

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7 January 2021

Delay of vaccinia virus-induced apoptosis in nonpermissive Chinese hamster ovary cells by the cowpox virus CHOhr and adenovirus E1B 19K genes.

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7 January 2021

Overexpression of bcl-2, apoptosis suppressing gene: Prolonged viable culture period of hybridoma and enhanced antibody production

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7 January 2021

Inducible expression of Bcl-XL restricts apoptosis resistance to the antibody secretion phase in hybridoma cultures

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7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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7 January 2021

Regulators of cell death

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7 January 2021

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

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7 January 2021

Overcoming apoptosis: new methods for improving protein-expression systems

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7 January 2021

Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults.

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7 January 2021

Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells

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7 January 2021

Dose-dependent reduction of apoptosis in nutrient-limited cultures of NS/0 myeloma cells transfected with the E1B-19K adenoviral gene.

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7 January 2021

Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage

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7 January 2021

bcl-2 expression in Spodoptera Frugiperda Sf-9 and Trichoplusia Ni BTI-Tn-5B1-4 insect cells: effect on recombinant protein expression and cell viability

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7 January 2021

Advanced modular self-inactivating lentiviral expression vectors for multigene interventions in mammalian cells and in vivo transduction

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7 January 2021

NSO myeloma cell death: Influence of bcl-2 overexpression

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7 January 2021

Caspase structure, proteolytic substrates, and function during apoptotic cell death

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7 January 2021

Nonviral vectors in the new millennium: delivery barriers in gene transfer

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7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

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7 January 2021

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

1 reference

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7 January 2021

Variable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cells

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7 January 2021

Essential role of optimal protein synthesis in preventing the apoptotic death of cultured B cell hybridomas

1 reference

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7 January 2021

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Large-scale mammalian cell culture

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7 January 2021

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Analysis of nutritional factors and physical conditions affecting growth and monoclonal antibody production of the hybridoma KB-26.5 cell line

1 reference

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7 January 2021

Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants

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7 January 2021

Study of caspase inhibitors for limiting death in mammalian cell culture

1 reference

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7 January 2021

Prevention of hybridoma cell death by bcl-2 during suboptimal culture conditions

1 reference

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7 January 2021

In hybridoma cultures, deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Cell death in bioreactors: a role for apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Apoptosis and its control in cell culture systems

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Serial killers: ordering caspase activation events in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Validation of biotechnology products and processes

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Co-expression of bcl-2 and bag-1, apoptosis suppressing genes, prolonged viable culture period of hybridoma and enhanced antibody production

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Bcl-2 mediated suppression of apoptosis in myeloma NS0 cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

The protection of hybridoma cells from apoptosis by caspase inhibition allows culture recovery when exposed to non-inducing conditions.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

The molecular biology of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Protective effect of viral homologues of bcl-2 on hybridoma cells under apoptosis-inducing conditions

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Kinetics of development of spontaneous apoptosis in B cell hybridoma cultures

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7176%2803%2900024-7

7 January 2021

10.1016/S1096-7176(03)00024-7

Identifiers

DOI

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6 August 2017

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