(Q35174032)

6 August 2017

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title

Possible role for memantine in protecting retinal ganglion cells from glaucomatous damage (English)

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6 August 2017

main subject

retinal ganglion cell

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Stuart A Lipton

1

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6 August 2017

publication date

1 April 2003

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6 August 2017

published in

Survey of Ophthalmology

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6 August 2017

volume

48 Suppl 1

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6 August 2017

page(s)

S38-46

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The mode of action of antagonists of the excitatory response to acetylcholine in Aplysia neurones

6 August 2017

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7 January 2021

Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells

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7 January 2021

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

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7 January 2021

Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels

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7 January 2021

Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons

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7 January 2021

Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism

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7 January 2021

Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

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7 January 2021

Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation

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7 January 2021

Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation

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7 January 2021

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7 January 2021

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

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7 January 2021

New perspectives on glaucoma

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Transcriptional or translational inhibition blocks low dose NMDA-mediated cell death

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7 January 2021

Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma

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7 January 2021

Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey

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7 January 2021

Neuroprotective therapy

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7 January 2021

Glycine potentiates the NMDA response in cultured mouse brain neurons

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7 January 2021

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7 January 2021

Potential and current use of N-methyl-D-aspartate (NMDA) receptor antagonists in diseases of aging

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7 January 2021

Memantine prevents HIV coat protein-induced neuronal injury in vitro

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7 January 2021

Prospects for clinically tolerated NMDA antagonists: open-channel blockers and alternative redox states of nitric oxide

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7 January 2021

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

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7 January 2021

Cysteine regulation of protein function--as exemplified by NMDA-receptor modulation.

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7 January 2021

The toxic effect of sodium L-glutamate on the inner layers of the retina.

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7 January 2021

Neuroprotection in acute ischaemic stroke. Current status and future potential

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7 January 2021

Saving the nerve from glaucoma: memantine to caspaces

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7 January 2021

Nitric oxide synthase in the human glaucomatous optic nerve head.

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7 January 2021

Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis

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7 January 2021

Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine

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7 January 2021

Glutaate-induced retinal degeneration in neonatal mice. Electron microscopy of the acutely evolving lesion

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7 January 2021

Efficacy and safety of memantine in patients with mild to moderate vascular dementia: a randomized, placebo-controlled trial (MMM 300).

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7 January 2021

Memantine reduces alterations to the mammalian retina, in situ, induced by ischemia

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7 January 2021

Neuroprotection by NMDA receptor antagonists in a variety of neuropathologies

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7 January 2021

Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

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7 January 2021

Delayed administration of memantine prevents N-methyl-D-aspartate receptor-mediated neurotoxicity

1 reference

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7 January 2021

Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents--toward an understanding of their favorable tolerability

1 reference

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7 January 2021

Neuroprotective effect of memantine demonstrated in vivo and in vitro.

1 reference

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7 January 2021

Molecular basis of glutamate toxicity in retinal ganglion cells.

1 reference

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7 January 2021

Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons

1 reference

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7 January 2021

Memantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine).

1 reference

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7 January 2021

Neuroprotective effect of memantine in different retinal injury models in rats

1 reference

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7 January 2021

Nitric oxide mediates N-methyl-D-aspartate receptor-induced activation of p21ras

1 reference

https://api.crossref.org/works/10.1016%2FS0039-6257%2803%2900008-0

7 January 2021

Evidence that the loss of the voltage-dependent Mg2+ block at the N-methyl-D-aspartate receptor underlies receptor activation during inhibition of neuronal metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0039-6257%2803%2900008-0

7 January 2021

Nitrate therapy may retard glaucomatous optic neuropathy, perhaps through modulation of glutamate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0039-6257%2803%2900008-0

7 January 2021

10.1016/S0039-6257(03)00008-0

Identifiers

DOI

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6 August 2017

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