(Q35175035)

6 August 2017

title

Increasing expression and decreasing degradation of SMN ameliorate the spinal muscular atrophy phenotype in mice (English)

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6 August 2017

main subject

spinal muscular atrophy

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1 reference

1 reference

Deborah Y Kwon

1

1 reference

6 August 2017

William W Motley

series ordinal

2

1 reference

6 August 2017

Kenneth H Fischbeck

series ordinal

3

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6 August 2017

Barrington G Burnett

series ordinal

4

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6 August 2017

publication date

21 June 2011

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6 August 2017

published in

Human Molecular Genetics

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6 August 2017

volume

20

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6 August 2017

issue

18

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6 August 2017

page(s)

3667-3677

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3159550/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

1 reference

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28 July 2018

1 reference

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Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy

27 September 2018

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27 September 2018

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A phase 1 study of the proteasome inhibitor bortezomib in pediatric patients with refractory leukemia: a Children's Oncology Group study.

27 September 2018

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Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy

27 September 2018

1 reference

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Pharmacological rescue of the dystrophin-glycoprotein complex in Duchenne and Becker skeletal muscle explants by proteasome inhibitor treatment

27 September 2018

1 reference

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Homozygous SMN1 deletions in unaffected family members and modification of the phenotype by SMN2.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3159550

Degradation of survival motor neuron (SMN) protein is mediated via the ubiquitin/proteasome pathway

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3159550

Neuromuscular defects in a Drosophila survival motor neuron gene mutant.

27 September 2018

1 reference

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The Drosophila bendless gene encodes a neural protein related to ubiquitin-conjugating enzymes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3159550

Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function

27 September 2018

1 reference

12 December 2020

SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN

1 reference

12 December 2020

Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate

1 reference

12 December 2020

Localized treatment with a novel FDA-approved proteasome inhibitor blocks the degradation of dystrophin and dystrophin-associated proteins in mdx mice

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDR288

1 reference

6 August 2017

1 reference

6 August 2017

1 reference