(Q35176426)

6 August 2017

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title

Genetic analysis of CD28 signaling (English)

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6 August 2017

Tiffani A Greene

1

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PubMed ID

12857994

6 August 2017

Virginia Smith Shapiro

series ordinal

2

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6 August 2017

1 January 2003

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6 August 2017

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6 August 2017

27

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6 August 2017

2-3

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6 August 2017

513-520

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https://scigraph.springernature.com/pub.10.1385/ir:27:2-3:513

6 August 2017

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cites work

Profound block in thymocyte development in mice lacking p56lck

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12 December 2020

Absence of B7-dependent responses in CD28-deficient mice

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12 December 2020

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

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12 December 2020

Regulation of the interleukin-2 gene

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12 December 2020

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

1 reference

12 December 2020

Identification of tyrosine phosphorylation sites in the CD28 cytoplasmic domain and their role in the costimulation of Jurkat T cells

1 reference

12 December 2020

Involvement of Rel, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 response element/AP-1 sequence in human T cells

1 reference

12 December 2020

B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation

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12 December 2020

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

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12 December 2020

Forward genetics in mammalian cells: functional approaches to gene discovery

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12 December 2020

The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28

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12 December 2020

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12 December 2020

A point mutation in CD28 distinguishes proliferative signals from survival signals

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12 December 2020

Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.

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12 December 2020

Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling

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12 December 2020

Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

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12 December 2020

Co-stimulation in T cell responses.

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12 December 2020

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

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12 December 2020

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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12 December 2020

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

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12 December 2020

CD28: a signalling perspective.

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12 December 2020

CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites

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12 December 2020

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

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12 December 2020

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

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12 December 2020

Coordinate transactivation of the interleukin-2 CD28 response element by c-Rel and ATF-1/CREB2.

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12 December 2020

The B7 and CD28 receptor families

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12 December 2020

Endogenous CD28 expressed on myeloma cells up-regulates interleukin-8 production: implications for multiple myeloma progression

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12 December 2020

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

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12 December 2020

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

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12 December 2020

Dissection of signaling pathways and cloning of new signal transducers in tyrosine kinase-induced pathways by genetic selection

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12 December 2020

Essential role for ZAP-70 in both positive and negative selection of thymocytes

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12 December 2020

Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo

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12 December 2020

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.

1 reference

12 December 2020

Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line

1 reference

12 December 2020

Nuclear factor of activated T cells and AP-1 are insufficient for IL-2 promoter activation: requirement for CD28 up-regulation of RE/AP.

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12 December 2020

Differential T cell costimulatory requirements in CD28-deficient mice

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12 December 2020

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

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12 December 2020

Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression

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12 December 2020

T cell co-stimulatory molecules other than CD28.

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12 December 2020

p53-independent role of MDM2 in TGF-beta1 resistance

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12 December 2020

Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

1 reference

12 December 2020

Cbl-b regulates the CD28 dependence of T-cell activation.

1 reference

12 December 2020

CD28 and T cell co-stimulation

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12 December 2020

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

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12 December 2020

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

1 reference

12 December 2020

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

1 reference

12 December 2020

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

1 reference

12 December 2020

Essential role of LAT in T cell development

1 reference

12 December 2020

Identifiers

DOI

10.1385/IR:27:2-3:513

1 reference

PubMed ID

12857994

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12857994