(Q35180084)

7 August 2017

title

Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice (English)

1 reference

7 August 2017

Masaki Naito

1

1 reference

7 August 2017

Junji Fujikura

2

1 reference

7 August 2017

Ken Ebihara

3

1 reference

7 August 2017

Fumiko Miyanaga

4

1 reference

7 August 2017

Hideki Yokoi

5

1 reference

7 August 2017

Toru Kusakabe

6

1 reference

7 August 2017

Yuji Yamamoto

7

1 reference

7 August 2017

Cheol Son

8

1 reference

7 August 2017

Masashi Mukoyama

9

1 reference

7 August 2017

Kiminori Hosoda

10

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7 August 2017

Kazuwa Nakao

11

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 August 2011

1 reference

7 August 2017

number of pages

9

1 reference

inferred from page(s)

published in

Diabetes

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7 August 2017

volume

60

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7 August 2017

issue

9

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7 August 2017

page(s)

2265-2273

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

7 August 2017

copyright license

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Mitochondrial biogenesis and peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) deacetylation by physical activity: intact adipocytokine signaling is required

1 reference

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Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Hyperleptinemia is required for the development of leptin resistance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin in human physiology and therapeutics

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin therapy in insulin-deficient type I diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Translational research of novel hormones: lessons from animal models and rare human diseases for common human diseases

13 July 2018

1 reference

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Making insulin-deficient type 1 diabetic rodents thrive without insulin

13 July 2018

1 reference

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Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c.

13 July 2018

1 reference

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Leptin in autoimmunity: many questions, some answers

13 July 2018

1 reference

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Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons

13 July 2018

1 reference

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AMP-activated protein kinase signaling in metabolic regulation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice

13 July 2018

1 reference

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Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

13 July 2018

1 reference

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Impact of genetic background on nephropathy in diabetic mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin effects on pancreatic beta-cell gene expression and function

13 July 2018

1 reference

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Diabetes, oxidative stress, and antioxidants: a review

13 July 2018

1 reference

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Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Decreased triglyceride-rich lipoproteins in transgenic skinny mice overexpressing leptin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Role of leptin in peroxisome proliferator-activated receptor gamma coactivator-1 expression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin,

13 July 2018

1 reference

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Leptin stimulates proliferation and TGF-beta expression in renal glomerular endothelial cells: potential role in glomerulosclerosis [seecomments]

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin and the regulation of body weight in mammals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Immunopathological influence of the Ay, db, ob and nu genes placed on the inbred NOD background as murine models for human type I diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Free radicals and diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Decrease of the inhibition of lipid peroxidation by glutathione-dependent system in erythrocytes of non-insulin dependent diabetics.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Beneficial effects of leptin on glycaemic and lipid control in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and a high-fat diet

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Ins2Akita mice exhibit hyperphagia and anxiety behavior via the melanocortin system.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Skeletal muscle AMP-activated protein kinase phosphorylation parallels metabolic phenotype in leptin transgenic mice under dietary modification

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Leptin as an adjunct of insulin therapy in insulin-deficient diabetes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Transgenic overexpression of leptin rescues insulin resistance and diabetes in a mouse model of lipoatrophic diabetes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161331

Prevention and reversal of renal injury by leptin in a new mouse model of diabetic nephropathy

27 September 2018

1 reference

12 December 2020

Tissue-Specific Effects of Central Leptin on the Expression of Genes Involved in Lipid Metabolism in Liver and White Adipose Tissue

1 reference

12 December 2020

Leptin accelerates autoimmune diabetes in female NOD mice

1 reference

12 December 2020

Long-term leptin-replacement therapy for lipoatrophic diabetes

1 reference

12 December 2020

Increased lipid peroxidation in type 2 poorly controlled diabetic patients

1 reference

12 December 2020

The BBZ/Wor rat: clinical characteristics of the diabetic syndrome

1 reference

12 December 2020

Development of radioimmunoassay for human leptin

1 reference

12 December 2020

A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice

1 reference

12 December 2020

Plasma leptin in diabetic and insulin-treated diabetic and normal rats

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB10-1795

1 reference

7 August 2017

1 reference

7 August 2017

1 reference