(Q35181632)

7 August 2017

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title

Molecular recognition in the protein C anticoagulant pathway (English)

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7 August 2017

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Dahlbäck B

1

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7 August 2017

Villoutreix BO

series ordinal

2

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7 August 2017

publication date

1 July 2003

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Journal of Thrombosis and Haemostasis

7 August 2017

published in

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7 August 2017

volume

1

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7 August 2017

issue

7

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7 August 2017

page(s)

1525-1534

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Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation

7 August 2017

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1 reference

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Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

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21 January 2018

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Endothelial cell protein C receptor plays an important role in protein C activation in vivo

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The crystal structure of the endothelial protein C receptor and a bound phospholipid

21 January 2018

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3-Dimensional structure of membrane-bound coagulation factor VIII: modeling of the factor VIII heterodimer within a 3-dimensional density map derived by electron crystallography

21 January 2018

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Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

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Crystal structures of the membrane-binding C2 domain of human coagulation factor V

21 January 2018

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Structure of the C2 domain of human factor VIII at 1.5 A resolution

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Identification of functionally important amino acid residues within the C2-domain of human factor V using alanine-scanning mutagenesis

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Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs

21 January 2018

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Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII

21 January 2018

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21 January 2018

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Peptide Bond Cleavages and Loss of Functional Activity during Inactivation of Factor Va and Factor VaR506Q by Activated Protein C

21 January 2018

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Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C

21 January 2018

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Secondary substrate-binding exosite in the serine protease domain of activated protein C important for cleavage at Arg-506 but not at Arg-306 in factor Va.

21 January 2018

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The C-terminal Region of the Factor V B-domain Is Crucial for the Anticoagulant Activity of Factor V

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21 January 2018

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Chemical synthesis of human protein S thrombin-sensitive module and first epidermal growth factor module

21 January 2018

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Binding site for C4b-binding protein in vitamin K-dependent protein S fully contained in carboxy-terminal laminin-G-type repeats. A study using recombinant factor IX-protein S chimeras and surface plasmon resonance

21 January 2018

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Localization of a hydrophobic binding site for anticoagulant protein S on the beta -chain of complement regulator C4b-binding protein.

21 January 2018

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Involvement of Amino Acid Residues 423–429 of Human Protein S in Binding to C4b-Binding Protein

21 January 2018

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A region of vitamin K-dependent protein S that binds to C4b binding protein (C4BP) identified using bacteriophage peptide display libraries

21 January 2018

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Crystal structure of a C-terminal fragment of growth arrest-specific protein Gas6. Receptor tyrosine kinase activation by laminin G-like domains

21 January 2018

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The amino-terminal module of the C4b-binding protein beta-chain contains the protein S-binding site

21 January 2018

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Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells

21 January 2018

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Binding Site for Blood Coagulation Factor Xa Involving Residues 311–325 in Factor Va

21 January 2018

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Definition of a factor Va binding site in factor Xa.

21 January 2018

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Factor IXa:factor VIIIa interaction. helix 330-338 of factor ixa interacts with residues 558-565 and spatially adjacent regions of the a2 subunit of factor VIIIa

21 January 2018

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The N-terminal epidermal growth factor-like domain of coagulation factor IX. Probing its functions in the activation of factor IX and factor X with a monoclonal antibody

21 January 2018

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Contribution of basic residues of the 70-80-loop to heparin binding and anticoagulant function of activated protein C.

21 January 2018

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Molecular characterization of an extended binding site for coagulation factor Va in the positive exosite of activated protein C.

21 January 2018

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Structural requirements of anticoagulant protein S for its binding to the complement regulator C4b-binding protein

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Homology models of the C domains of blood coagulation factors V and VIII: a proposed membrane binding mode for FV and FVIII C2 domains

21 January 2018

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A model describing the inactivation of factor Va by APC: bond cleavage, fragment dissociation, and product inhibition

21 January 2018

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Cleavage of factor VIII heavy chain is required for the functional interaction of a2 subunit with factor IXA

21 January 2018

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The C4b-binding protein–protein S interaction is hydrophobic in nature

21 January 2018

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Three-dimensional model of the SHBG-like region of anticoagulant protein S: New structure-function insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00299.X

C4b-binding protein (C4BP) beta-chain Short Consensus Repeat-2 specifically contributes to the interaction of C4BP with protein S

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00299.X

The connecting segment between both epidermal growth factor-like domains in blood coagulation factor IX contributes to stimulation by factor VIIIa and its isolated A2 domain

21 January 2018

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10.1046/J.1538-7836.2003.00299.X

21 January 2018

Identifiers

DOI

1 reference

7 August 2017

1 reference