(Q35182991)

English

A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport

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6 February 2020

A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport (English)

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6 February 2020

transmembrane transport

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transmembrane protein

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neurotransmitter

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based on heuristic

inferred from title

16

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6 February 2020

12

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6 February 2020

Sergei Y Noskov

14

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6 February 2020

Louis J. De Felice

15

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6 February 2020

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L Keith Henry

1

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6 February 2020

Hideki Iwamoto

2

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6 February 2020

Julie R Field

3

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6 February 2020

Kristian Kaufmann

4

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6 February 2020

Eric S Dawson

5

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6 February 2020

Miriam T Jacobs

6

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6 February 2020

Chelsea Adams

7

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6 February 2020

Bruce Felts

8

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6 February 2020

Igor Zdravkovic

9

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6 February 2020

Vanessa Armstrong

10

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6 February 2020

Steven Combs

11

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6 February 2020

Gary Rudnick

13

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6 February 2020

Randy D Blakely

17

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6 February 2020

language of work or name

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publication date

5 July 2011

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6 February 2020

number of pages

14

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Journal of Biological Chemistry

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6 February 2020

286

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6 February 2020

35

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6 February 2020

30823-30836

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21730057%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

The mechanism of sodium and substrate release from the binding pocket of vSGLT

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Reconstructing a chloride-binding site in a bacterial neurotransmitter transporter homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

A glutamine residue conserved in the neurotransmitter:sodium:symporters is essential for the interaction of chloride with the GABA transporter GAT-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Transmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Structure and function of Na(+)-symporters with inverted repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Structure and Mechanism of a Na+-Independent Amino Acid Transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

CHARMM-GUI Membrane Builder for mixed bilayers and its application to yeast membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

CHARMM: the biomolecular simulation program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Molecular basis of transport and regulation in the Na(+)/betaine symporter BetP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Molecular mechanism of ion-ion and ion-substrate coupling in the Na+-dependent leucine transporter LeuT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Mechanism for alternating access in neurotransmitter transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

The binding sites for cocaine and dopamine in the dopamine transporter overlap

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Binding of serotonin to the human serotonin transporter. Molecular modeling and experimental validation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Mechanism of chloride interaction with neurotransmitter:sodium symporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Discontinuous membrane helices in transport proteins and their correlation with function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Calcium-dependent interactions of the human norepinephrine transporter with syntaxin 1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Scalable molecular dynamics with NAMD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines and non-amphetamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Regulation of K-Cl cotransport: from function to genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Dopamine transporters depolarize neurons by a channel mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Proton binding to proteins: pK(a) calculations with explicit and implicit solvent models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Revisiting free energy calculations: a theoretical connection to MM/PBSA and direct calculation of the association free energy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Regulating the conducting states of a mammalian serotonin transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

A graph-theory algorithm for rapid protein side-chain prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Flux coupling in the human serotonin transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Contribution of the Na-K-Cl cotransporter on GABA(A) receptor-mediated presynaptic depolarization in excitatory nerve terminals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Measurement of transient currents from neurotransmitter transporters expressed in Xenopus oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Amino acid residues that control pH modulation of transport-associated current in mammalian serotonin transporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Mechanistic analyses of ion dependences in a high-affinity human serotonin transport system in transfected murine fibroblast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

The Third Transmembrane Domain of the Serotonin Transporter Contains Residues Associated with Substrate and Cocaine Binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Drug targets in the embryo. Studies on the cocaine- and antidepressant-sensitive serotonin transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

A cocaine-sensitive Drosophila serotonin transporter: cloning, expression, and electrophysiological characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Uptake of Serotonin in Blood Platelets in vitro. I: The Effects of Chloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Mechanism of transport and storage of neurotransmitters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Distribution of serotonin 5-HT1C receptor mRNA in adult rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Cloning and expression of a functional serotonin transporter from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

Expression of mRNA (D2) encoding a protein involved in amino acid transport in S3 proximal tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

An [Na+ + K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

13 July 2018

GABA efflux from synaptosomes: effects of membrane potential, and external GABA and cations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Serotonin transporter function and pharmacology are sensitive to expression level: evidence for an endogenous regulatory factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Serotonin and cocaine-sensitive inactivation of human serotonin transporters by methanethiosulfonates targeted to transmembrane domain I.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Ionic interactions in the Drosophila serotonin transporter identify it as a serotonin channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Molecular mechanism of substrate specificity in the bacterial neutral amino acid transporter LeuT.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Evidence that NADP+ is the physiological cofactor of ADP-L-glycero-D-mannoheptose 6-epimerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Structure and function of extracellular loop 4 of the serotonin transporter as revealed by cysteine-scanning mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

The cytoplasmic substrate permeation pathway of serotonin transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Conducting states of a mammalian serotonin transporter.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

ROSETTALIGAND: protein-small molecule docking with full side-chain flexibility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Potential of mean force and pKa profile calculation for a lipid membrane-exposed arginine side chain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162443

27 September 2018

Mechanism of Transport and Storage of Neurotransmitter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Stabilization of the Catalytic Thiolate in a Mammalian Glutaredoxin: Structure, Dynamics and Electrostatics of Reduced Pig Glutaredoxin and its Mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

Determination of Electrostatic Parameters for a Polarizable Force Field Based on the Classical Drude Oscillator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250308

21 January 2018

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/21730057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of chloride ion in platelet serotonin transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/21730057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

External cysteine residues in the serotonin transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21730057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.250308

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21730057%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21730057%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21730057%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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