(Q35187128)

7 August 2017

title

Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis (English)

1 reference

7 August 2017

Meredith J Goertz

1

1 reference

7 August 2017

Zhuoru Wu

2

1 reference

7 August 2017

Teresa D Gallardo

3

1 reference

7 August 2017

F Kent Hamra

4

1 reference

7 August 2017

Diego H Castrillon

5

1 reference

7 August 2017

language of work or name

English

0 references

publication date

25 August 2011

1 reference

Journal of Clinical Investigation

7 August 2017

published in

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7 August 2017

volume

121

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7 August 2017

issue

9

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7 August 2017

page(s)

3456-3466

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The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

7 August 2017

cites work

1 reference

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EGR4 displays both a cell- and intracellular-specific localization pattern in the developing murine testis

13 July 2018

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Loss of Lhx1 activity impacts on the localization of primordial germ cells in the mouse.

13 July 2018

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Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1

13 July 2018

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GATA Switches as Developmental Drivers

13 July 2018

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The key role of vitamin A in spermatogenesis

13 July 2018

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13 July 2018

The genetics of ageing

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Functional hierarchy and reversibility within the murine spermatogenic stem cell compartment

13 July 2018

1 reference

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Phenotypic plasticity of mouse spermatogonial stem cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

FoxO3 regulates neural stem cell homeostasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Spermatogonial stem cells derived from infertile Wv/Wv mice self-renew in vitro and generate progeny following transplantation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Human testicular (non)seminomatous germ cell tumours: the clinical implications of recent pathobiological insights.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Deletion of the pluripotency-associated Tex19.1 gene causes activation of endogenous retroviruses and defective spermatogenesis in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

GDNF and GFRalpha: a versatile molecular complex for developing neurons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Regulation of spermatogonial stem cell self-renewal in mammals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

FoxO transcription factors in the maintenance of cellular homeostasis during aging

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

GDNF-mediated signaling via RET tyrosine 1062 is essential for maintenance of spermatogonial stem cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Specificity of the requirement for Foxo3 in primordial follicle activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Glial cell line-derived neurotrophic factor regulation of genes essential for self-renewal of mouse spermatogonial stem cells is dependent on Src family kinase signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Generation of a germ cell-specific mouse transgenic Cre line, Vasa-Cre

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Akt mediates self-renewal division of mouse spermatogonial stem cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Identifying genes important for spermatogonial stem cell self-renewal and survival

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Glial cell-line derived neurotrophic factor-mediated RET signaling regulates spermatogonial stem cell fate

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Essential role of Plzf in maintenance of spermatogonial stem cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Plzf is required in adult male germ cells for stem cell self-renewal

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Unique chromatin remodeling and transcriptional regulation in spermatogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Gonadal expression of c-kit encoded at the W locus of the mouse

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

FOXO transcription factors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Dppa2 and Dppa4 are closely linked SAP motif genes restricted to pluripotent cells and the germ line.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Infertility associated with incomplete spermatogenic arrest and oligozoospermia in Egr4-deficient mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163967

Regulation of proliferation and differentiation in spermatogonial stem cells: the role of c-kit and its ligand SCF

27 September 2018

1 reference

12 December 2020

Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production

1 reference

12 December 2020

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

12 December 2020

Functional identification of the actual and potential stem cell compartments in mouse spermatogenesis

1 reference

12 December 2020

High-throughput real-time quantitative reverse transcription PCR

1 reference

12 December 2020

Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI57984

1 reference

7 August 2017

1 reference

7 August 2017

1 reference