(Q35190723)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24942694%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Cellular and molecular mechanisms underlying NOD2 risk-associated polymorphisms in Crohn's disease (English)

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20 March 2020

0 references

2

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20 March 2020

author name string

Warren Strober

1

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20 March 2020

Ivan Fuss

3

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20 March 2020

Atsushi Kitani

4

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20 March 2020

Tomohiro Watanabe

5

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20 March 2020

publication date

1 July 2014

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20 March 2020

published in

Immunological Reviews

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20 March 2020

volume

260

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20 March 2020

issue

1

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20 March 2020

page(s)

249-260

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Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

20 March 2020

cites work

1 reference

Signalling pathways and molecular interactions of NOD1 and NOD2

21 January 2018

1 reference

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

Crohn's disease and the NOD2 gene: a role for paneth cells

21 January 2018

1 reference

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

21 January 2018

1 reference

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

1 reference

Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

21 January 2018

1 reference

Nod2 is required for the regulation of commensal microbiota in the intestine

21 January 2018

1 reference

Nod2: a key regulator linking microbiota to intestinal mucosal immunity

21 January 2018

1 reference

Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

21 January 2018

1 reference

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

21 January 2018

1 reference

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

1 reference

Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease.

21 January 2018

1 reference

Mouse Paneth cell antimicrobial function is independent of Nod2.

21 January 2018

1 reference

Enteric defensins are essential regulators of intestinal microbial ecology

21 January 2018

1 reference

Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

21 January 2018

1 reference

Nod2 is essential for temporal development of intestinal microbial communities.

21 January 2018

1 reference

Host genetics and environmental factors regulate ecological succession of the mouse colon tissue-associated microbiota

21 January 2018

1 reference

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells

21 January 2018

1 reference

Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis

21 January 2018

1 reference

Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases

21 January 2018

1 reference

Nod2 deficiency is associated with an increased mucosal immunoregulatory response to commensal microorganisms

21 January 2018

1 reference

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

21 January 2018

1 reference

Influences of intestinal bacteria in human inflammatory bowel disease

21 January 2018

1 reference

Differences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitis

21 January 2018

1 reference

Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum

21 January 2018

1 reference

Low counts of Faecalibacterium prausnitzii in colitis microbiota.

21 January 2018

1 reference

Microbiota in pediatric inflammatory bowel disease.

21 January 2018

1 reference

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

21 January 2018

1 reference

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

21 January 2018

1 reference

The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

21 January 2018

1 reference

Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease

21 January 2018

1 reference

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

21 January 2018

1 reference

CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

21 January 2018

1 reference

Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae

21 January 2018

1 reference

Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death

21 January 2018

1 reference

Replication of Crohn's disease-associated AIEC within macrophages is dependent on TNF-α secretion

21 January 2018

1 reference

AIEC colonization and pathogenicity: influence of previous antibiotic treatment and preexisting inflammation.

21 January 2018

1 reference

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

21 January 2018

1 reference

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

21 January 2018

1 reference

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 January 2018

1 reference

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

1 reference

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

1 reference

NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction

21 January 2018

1 reference

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

21 January 2018

1 reference

The fundamental basis of inflammatory bowel disease

21 January 2018

1 reference

Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches.

21 January 2018

1 reference

Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance

21 January 2018

1 reference

Chronic stimulation of Nod2 mediates tolerance to bacterial products

21 January 2018

1 reference

Secretory mediators regulate Nod2-induced tolerance in human macrophages

21 January 2018

1 reference

NF-κB1 inhibits NOD2-induced cytokine secretion through ATF3-dependent mechanisms

21 January 2018

1 reference

Negative regulation of Toll-like-receptor signaling by IRF-4.

21 January 2018

1 reference

Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease

21 January 2018

1 reference

Altered gut microbiota composition in immune-impaired Nod2(-/-) mice

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/IMR.12193

1 reference

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20 March 2020

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