(Q35197004)

7 August 2017

MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres (English)

1 reference

7 August 2017

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Carola Garcia de Vinuesa

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Alvin Pratama

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Monika Srivastava

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Naomi J Williams

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Ilenia Papa

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Sau K Lee

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Xuyen T Dinh

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Margaret A Jordan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Jimmy L Zhao

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Rafael Casellas

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Vicki Athanasopoulos

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

language of work or name

English

0 references

publication date

6 March 2015

1 reference

7 August 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

6436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

5 June 2020

copyright license

start time

6 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms7436

0 references

cites work

miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation

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Fate mapping reveals origin and dynamics of lymph node follicular dendritic cells

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13 July 2018

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Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

13 July 2018

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The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression.

13 July 2018

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MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation

13 July 2018

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MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

13 July 2018

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Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.

13 July 2018

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Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation

13 July 2018

1 reference

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Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation

13 July 2018

1 reference

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miR-146a controls the resolution of T cell responses in mice

13 July 2018

1 reference

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Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas

13 July 2018

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Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.

13 July 2018

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Increased frequency of circulating follicular helper T cells in patients with rheumatoid arthritis

13 July 2018

1 reference

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Follicular helper T cells in immunity and systemic autoimmunity

13 July 2018

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Regulation of monocyte functional heterogeneity by miR-146a and Relb

13 July 2018

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Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

13 July 2018

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Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene.

13 July 2018

1 reference

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Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells

13 July 2018

1 reference

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Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection

13 July 2018

1 reference

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Foxp3+ follicular regulatory T cells control the germinal center response.

13 July 2018

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Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

13 July 2018

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Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development

13 July 2018

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A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus.

13 July 2018

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MicroRNA-146a inhibits glioma development by targeting Notch1

13 July 2018

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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

13 July 2018

1 reference

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NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

13 July 2018

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A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center

13 July 2018

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miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

13 July 2018

1 reference

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Follicular helper CD4 T cells (TFH)

13 July 2018

1 reference

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SLAM family receptors and SAP adaptors in immunity.

13 July 2018

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Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion

13 July 2018

1 reference

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Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

13 July 2018

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Serum and urinary cell-free MiR-146a and MiR-155 in patients with systemic lupus erythematosus

13 July 2018

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Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses

13 July 2018

1 reference

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Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance.

13 July 2018

1 reference

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Regulation of the IL-21 gene by the NF-κB transcription factor c-Rel

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Regulation of microRNA expression and abundance during lymphopoiesis

13 July 2018

1 reference

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Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Bcl6 mediates the development of T follicular helper cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Follicular helper T cells are required for systemic autoimmunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Expression of microRNA-146 in rheumatoid arthritis synovial tissue

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

ICOS co-stimulatory receptor is essential for T-cell activation and function

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

T-cell co-stimulation through B7RP-1 and ICOS

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

A cell type-specific enhancer in the human B7.1 gene regulated by NF-kappaB

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Notch signaling regulates follicular helper T cell differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Follicular helper T cells may play an important role in the severity of primary Sjögren's syndrome

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

c-Rel is essential for B lymphocyte survival and cell cycle progression.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366510

MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

26 September 2018

1 reference

12 December 2020

Single-cell phospho-protein analysis by flow cytometry

1 reference

12 December 2020

Role of SLAM in NKT cell development revealed by transgenic complementation in NOD mice

1 reference

12 December 2020

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

1 reference

12 December 2020

T suppressor lymphocytes inhibit NF-kappa B-mediated transcription of CD86 gene in APC

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS7436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25743066%20AND%20SRC:MED&resulttype=core&format=json