(Q35197893)

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Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 August 2017

Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

author name string

Alex Jones

1

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Sandeep Kumar

2

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Ning Zhang

3

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Zongzhong Tong

4

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Jia-Hui Yang

5

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Carl Watt

6

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

James Anderson

7

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Amrita

8

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Heather Fillerup

9

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Manabu McCloskey

10

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Ling Luo

11

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Zhenglin Yang

12

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Balamurali Ambati

13

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Robert Marc

14

1 reference

Europe PubMed Central

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7 August 2017

Chio Oka

15

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Kang Zhang

16

1 reference

Europe PubMed Central

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7 August 2017

Yingbin Fu

17

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

language of work or name

0 references

publication date

15 August 2011

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

108

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

35

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

14578-14583

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Risk- and non-risk-associated variants at the 10q26 AMD locus influence ARMS2 mRNA expression but exclude pathogenic effects due to protein deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Age-related macular degeneration-associated variants at chromosome 10q26 do not significantly alter ARMS2 and HTRA1 transcript levels in the human retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

HtrA proteins as targets in therapy of cancer and other diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Identification of novel substrates for the serine protease HTRA1 in the human RPE secretome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

The dynamic nature of Bruch's membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Molecular pathology of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

HtrA1: a novel regulator of physiological and pathological matrix mineralization?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

HTRA1 promoter polymorphism in wet age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Serum elastin-derived peptides in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Meta-analysis of genome scans of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

The origins of polypoidal choroidal vasculopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Expression of pigment epithelium derived factor and vascular endothelial growth factor in choroidal neovascular membranes and polypoidal choroidal vasculopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Analysis of the VMD2 promoter and implication of E-box binding factors in its regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Age-related macular degeneration--a genome scan in extended families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Vascular endothelial growth factors and angiogenesis in eye disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

The HtrA Family of Proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Basal linear deposit and large drusen are specific for early age-related maculopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Enhancer and promoter chimeras in plasmids designed for intramuscular injection: a comparative in vivo and in vitro study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

Indocyanine green videoangiography of idiopathic polypoidal choroidal vasculopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

28 July 2018

ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Polypoidal choroidal vasculopathy masquerading as neovascular age-related macular degeneration refractory to ranibizumab

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Three major loci involved in age-related macular degeneration are also associated with polypoidal choroidal vasculopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Polypoidal choroidal vasculopathy: an angiographic discussion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Refractory neovascular age-related macular degeneration secondary to polypoidal choroidal vasculopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Correlation between CFH Y402H and HTRA1 rs11200638 genotype to typical exudative age-related macular degeneration and polypoidal choroidal vasculopathy phenotype in the Japanese population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

The HtrA1 promoter polymorphism, smoking, and age-related macular degeneration in multiple case-control samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Clinicopathologic findings in polypoidal choroidal vasculopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

An enhancer/promoter combination strengthens the expression of blood-coagulation factor VIII in non-viral expression vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Association analysis of CFH, C2, BF, and HTRA1 gene polymorphisms in Chinese patients with polypoidal choroidal vasculopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Human HtrA1 in the archived eyes with age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Intravitreal bevacizumab (Avastin) with or without photodynamic therapy for the treatment of polypoidal choroidal vasculopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Efficacy of intravitreal bevacizumab for polypoidal choroidal vasculopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Hybrid cytomegalovirus enhancer-h1 promoter-based plasmid and baculovirus vectors mediate effective RNA interference.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Binding of proteins to the PDZ domain regulates proteolytic activity of HtrA1 serine protease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Polypoidal choroidal vasculopathy treated with macular translocation: clinical pathological correlation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167497

26 September 2018

Interactive expressions of HtrA1 and VEGF in human vitreous humors and fetal RPE cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21844367

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Idiopathic polypoidal choroidal vasculopathy (IPCV)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21844367

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aqueous humor levels of vascular endothelial growth factor and pigment epithelium-derived factor in polypoidal choroidal vasculopathy and choroidal neovascularization

1 reference

https://pubmed.ncbi.nlm.nih.gov/21844367

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1102853108

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

2011PNAS..10814578J

0 references

release_f6korcvtp5gm3ifxmjnkcwupfa

1 reference

https://api.fatcat.wiki/v0/release/f6korcvtp5gm3ifxmjnkcwupfa

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

ResearchGate publication ID

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