(Q35200826)

7 August 2017

title

Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins (English)

1 reference

7 August 2017

P J Moos

1

1 reference

7 August 2017

K Edes

series ordinal

2

1 reference

7 August 2017

F A Fitzpatrick

series ordinal

3

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 August 2000

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

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7 August 2017

volume

97

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7 August 2017

issue

16

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7 August 2017

page(s)

9215-9220

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Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

7 August 2017

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13 July 2018

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13 July 2018

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Pyrrolidine dithiocarbamate prevents p53 activation and promotes p53 cysteine residue oxidation.

13 July 2018

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13 July 2018

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13 July 2018

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Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein.

13 July 2018

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Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells

13 July 2018

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13 July 2018

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Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell

13 July 2018

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Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect

13 July 2018

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Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Activation of heat shock factor by alkylating agents is triggered by glutathione depletion and oxidation of protein thiols

13 July 2018

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Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents

13 July 2018

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Redox modulation of p53 conformation and sequence-specific DNA binding in vitro.

13 July 2018

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A comparison of the biological activities of wild-type and mutant p53.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

13 July 2018

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p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma

13 July 2018

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Requirement of a reactive alpha, beta-unsaturated carbonyl for inhibition of tumor growth and induction of differentiation by "A" series prostaglandins.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines

13 July 2018

1 reference

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Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Suppression of human colorectal carcinoma cell growth by wild-type p53

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

The p53 tumour suppressor gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Correlation between the conformational phenotype of p53 and its subcellular location

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Cancer. p53, guardian of the genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Oncogenic forms of p53 inhibit p53-regulated gene expression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

p53 function and dysfunction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Formation of glutathione conjugates of prostaglandin A1 in human red blood cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Nuclear localization is essential for the activity of p53 protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16848

Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms

15 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

Interactions of prostaglandin A2 with the glutathione-mediated biotransformation system

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

Prostaglandin A2 protein interactions and inhibition of cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

Inhibition of tumour growth in vivo and in vitro by prostaglandin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

Albumin-lipid interactions: prostaglandin stability as a probe for characterizing binding sites on vertebrate albumins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

Metabolic dehydration of prostaglandin E2 and cellular uptake of the dehydration product: correlation with prostaglandin E2-induced growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

delta 12-Prostaglandin J2, an ultimate metabolite of prostaglandin D2 exerting cell growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

Formation of reactive cyclopentenone compounds in vivo as products of the isoprostane pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

Cellular response to DNA damage from a potent carcinogen involves stabilization of p53 without induction of p21(waf1/cip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.160241897

Effect of glutathione content on cellular uptake and growth inhibitory activity of prostaglandin A2 in L-1210 cells

21 January 2018

1 reference

12 December 2020

Frequently elevated content of immunochemically defined wild-type p53 protein in colorectal adenomas

1 reference

12 December 2020

Mutations in p53 produce a common conformational effect that can be detected with a panel of monoclonal antibodies directed toward the central part of the p53 protein

1 reference

12 December 2020

Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer

1 reference

12 December 2020

Taxanes propagate apoptosis via two cell populations with distinctive cytological and molecular traits

1 reference

12 December 2020

Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro

1 reference

12 December 2020

Induction of 68,000-dalton heat shock proteins by cyclopentenone prostaglandins. Its association with prostaglandin-induced G1 block in cell cycle progression

1 reference

12 December 2020

Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.160241897

1 reference

7 August 2017

0 references

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7 August 2017

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