(Q35200879)

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Downregulation of blood-brain barrier phenotype by proinflammatory cytokines involves NADPH oxidase-dependent ROS generation: consequences for interendothelial adherens and tight junctions.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Downregulation of blood-brain barrier phenotype by proinflammatory cytokines involves NADPH oxidase-dependent ROS generation: consequences for interendothelial adherens and tight junctions (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

blood–brain barrier

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Keith D Rochfort

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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Laura E Collins

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Ronan P Murphy

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Philip M Cummins

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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3 July 2014

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Europe PubMed Central

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21 March 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

e101815

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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Creative Commons Attribution 4.0 International

3 July 2014

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April 2022 Public Data File from Crossref

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1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4081725/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Blood-brain barrier and traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Effects of fumaric acid esters on blood-brain barrier tight junction proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Effects of interleukin-6 on the expression of tight junction proteins in isolated cerebral microvessels from yearling and adult sheep

1 reference

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13 July 2018

Cytokine-induced oxidative stress in cardiac inflammation and heart failure-how the ubiquitin proteasome system targets this vicious cycle

1 reference

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13 July 2018

Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells

1 reference

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13 July 2018

Breaking the barrier in stroke: what should we know? A mini-review.

1 reference

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13 July 2018

Neuroinflammatory Cytokines-The Common Thread in Alzheimer's Pathogenesis

1 reference

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13 July 2018

Occludin: one protein, many forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier.

1 reference

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13 July 2018

Blood–brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Roles of IL-6-gp130 Signaling in Vascular Inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Jak/STAT signaling pathway regulates nox1 and nox4-based NADPH oxidase in human aortic smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Oxidative mechanisms of IL-4-induced IL-6 expression in vascular endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Pro-inflammatory cytokine TNF-alpha as a neuroprotective agent in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Inflammatory cytokines in acute ischemic stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Oxytocin attenuates NADPH-dependent superoxide activity and IL-6 secretion in macrophages and vascular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Evidence that N-acetylcysteine inhibits TNF-alpha-induced cerebrovascular endothelin-1 upregulation via inhibition of mitogen- and stress-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Cytokine-regulated protein degradation by the ubiquitination system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

TNF alpha potentiates glutamate neurotoxicity by inhibiting glutamate uptake in organotypic brain slice cultures: neuroprotection by NF kappa B inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Endothelial dysfunction and reactive oxygen species production in ischemia/reperfusion and nitrate tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Effects of TNF-alpha and IFN-gamma on nitric oxide-induced neurotoxicity in the mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Role of NAD(P)H oxidase in angiotensin II-induced JAK/STAT signaling and cytokine induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Increased permeability of primary cultured brain microvessel endothelial cell monolayers following TNF-alpha exposure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Interleukin-1 modulates protein tyrosine phosphatase activity and permeability of brain endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Measurement of protein using bicinchoninic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

In vivo relationship of tumor necrosis factor-alpha to blood-brain barrier damage in patients with active multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

13 July 2018

Shear stress is a positive regulator of thimet oligopeptidase (EC3.4.24.15) in vascular endothelial cells: consequences for MHC1 levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

Role of the JAK/STAT signaling pathway in the pathogenesis of acute myocardial infarction in rats and its effect on NF-κB expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

Regulation of adhesion molecules expression in TNF‐α‐stimulated brain microvascular endothelial cells by tanshinone IIA: involvement of NF‐κB and ROS generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

Tumour necrosis factor-alpha affects blood-brain barrier permeability and tight junction-associated occludin in acute liver failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

Tumor necrosis factor-alpha mediates the blood-brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells

1 reference

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26 September 2018

Radiation-induced astrogliosis and blood-brain barrier damage can be abrogated using anti-TNF treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

Down-regulation of neprilysin (EC3.4.24.11) expression in vascular endothelial cells by laminar shear stress involves NADPH oxidase-dependent ROS production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

HO-2 provides endogenous protection against oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081725

26 September 2018

The effect of TNF-alpha and IL-6 on the permeability of the rat blood-retinal barrier in vivo.

1 reference

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26 September 2018

Roles of Rho/ROCK and MLCK in TNF-α-induced changes in endothelial morphology and permeability

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0101815

21 January 2018

TNF-alpha and IL-1beta increase pericyte/endothelial cell co-culture permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/24992685

12 December 2020

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inferred from PubMed ID database lookup

TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24992685

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 increases endothelial permeability in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/24992685

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN gamma-dependent SOCS3 expression inhibits IL-6-induced STAT3 phosphorylation and differentially affects IL-6 mediated transcriptional responses in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24992685

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide auto-augments superoxide formation and upregulates gp91(phox) expression in porcine pulmonary artery endothelial cells: inhibition by iloprost

1 reference

https://pubmed.ncbi.nlm.nih.gov/24992685

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inferred from PubMed ID database lookup

Stabilization of brain microvascular endothelial barrier function by shear stress involves VE-cadherin signaling leading to modulation of pTyr-occludin levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/24992685

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inferred from PubMed ID database lookup

Role of glutathione redox cycle in TNF-alpha-mediated endothelial cell dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/24992685

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inferred from PubMed ID database lookup

Stat3 mediates interleukin-6 [correction of interelukin-6] inhibition of human endothelial nitric-oxide synthase expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24992685

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0101815

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

2014PLoSO...9j1815R

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24992685%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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