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The control of trunk Hox specificity and activity by Extradenticle
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
title
The control of trunk Hox specificity and activity by Extradenticle
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
main subject
Sex combs reduced Dmel_CG1030
1 reference
stated in
GOA release 2020-03-11
Extradenticle Dmel_CG8933
1 reference
stated in
GOA release 2020-03-11
author name string
H D Ryoo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
R S Mann
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
publication date
1 July 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
published in
Genes & Development
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
volume
13
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
page(s)
1704-1716
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
issue
13
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
cites work
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13 July 2018
Control of the nuclear localization of Extradenticle by competing nuclear import and export signals
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A comparison of in vivo and in vitro DNA-binding specificities suggests a new model for homeoprotein DNA binding in Drosophila embryos
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13 July 2018
Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex
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Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation
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Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex
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Control of antennal versus leg development in Drosophila.
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The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila
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Functional and regulatory interactions between Hox and extradenticle genes
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Regulation of segmentation and segmental identity by Drosophila homeoproteins: the role of DNA binding in functional activity and specificity.
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Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster.
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Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins
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13 July 2018
A model for extradenticle function as a switch that changes HOX proteins from repressors to activators
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13 July 2018
Distinct HOX N-terminal arm residues are responsible for specificity of DNA recognition by HOX monomers and HOX.PBX heterodimers
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Nuclear import of the homeodomain protein extradenticle in response to Wg and Dpp signalling.
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13 July 2018
Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins
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13 July 2018
Salivary duct determination in Drosophila: roles of the EGF receptor signalling pathway and the transcription factors fork head and trachealess
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13 July 2018
An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif
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PubMed Central
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13 July 2018
Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus
1 reference
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PubMed Central
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13 July 2018
A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer
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PubMed Central
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13 July 2018
Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA.
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PubMed Central
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13 July 2018
extradenticle determines segmental identities throughout Drosophila development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Structure of the even-skipped homeodomain complexed to AT-rich DNA: new perspectives on homeodomain specificity
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PubMed Central
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13 July 2018
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
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PubMed Central
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13 July 2018
Functional specificity of the Antennapedia homeodomain
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PubMed Central
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13 July 2018
The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences
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PubMed Central
reference URL
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13 July 2018
Two homeo domain proteins bind with similar specificity to a wide range of DNA sites in Drosophila embryos.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins.
1 reference
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PubMed Central
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13 July 2018
Functional differences between HOX proteins conferred by two residues in the homeodomain N-terminal arm.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Genes controlling segmental specification in the Drosophila thorax
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Regulation of the Ultrabithorax gene of Drosophila by other bithorax complex genes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
A molecular gradient in early Drosophila embryos and its role in specifying the body pattern.
1 reference
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PubMed Central
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13 July 2018
A homeodomain substitution changes the regulatory specificity of the deformed protein in Drosophila embryos
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
The caudal gene product is a direct activator of fushi tarazu transcription during Drosophila embryogenesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Expression of the caudal gene in the germ line of Drosophila: formation of an RNA and protein gradient during early embryogenesis
1 reference
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PubMed Central
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13 July 2018
Functional dissection of Ultrabithorax proteins in D. melanogaster.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
abdA expression in Drosophila embryos
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions
1 reference
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PubMed Central
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13 July 2018
Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
13 July 2018
The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
13 July 2018
The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
13 July 2018
New motif in PBX genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
13 July 2018
Mapping functional specificity in the Dfd and Ubx homeo domains
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Organogenesis in Drosophila melanogaster: embryonic salivary gland determination is controlled by homeotic and dorsoventral patterning genes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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13 July 2018
Homeobox genes and axial patterning
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
13 July 2018
Eve and ftz regulate a wide array of genes in blastoderm embryos: the selector homeoproteins directly or indirectly regulate most genes in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
26 September 2018
Generation of multiple antagonistic domains along the proximodistal axis during Drosophila leg development.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
Regulation and formation of the Drosophila salivary glands.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
Nuclear translocation of extradenticle requires homothorax, which encodes an extradenticle-related homeodomain protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
Drosophila Hox complex downstream targets and the function of homeotic genes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
Switching the in vivo specificity of a minimal Hox-responsive element.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
Nucleocytoplasmic localisation of extradenticle protein is spatially regulated throughout development in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
26 September 2018
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
26 September 2018
The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
Control of Drosophila adult pattern by extradenticle.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
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26 September 2018
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316852
retrieved
26 September 2018
Structural basis of Hox specificity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10398683
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/GAD.13.13.1704
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
PMCID
316852
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
PubMed ID
10398683
1 reference
stated in
Europe PubMed Central
PubMed ID
10398683
retrieved
7 August 2017
ResearchGate publication ID
12899995
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