(Q35205903)

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Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man (English)

1 reference

Europe PubMed Central

7 August 2017

author name string

A F Hofmann

1

1 reference

Europe PubMed Central

7 August 2017

G Molino

2

1 reference

Europe PubMed Central

7 August 2017

M Milanese

3

1 reference

Europe PubMed Central

7 August 2017

G Belforte

4

1 reference

Europe PubMed Central

7 August 2017

language of work or name

0 references

publication date

1 April 1983

1 reference

Europe PubMed Central

7 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

7 August 2017

71

1 reference

Europe PubMed Central

7 August 2017

1003-1022

1 reference

Europe PubMed Central

7 August 2017

4

1 reference

Europe PubMed Central

7 August 2017

A linear method for determining liver sinusoidal and extravascular volumes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Bile acid output and the interdigestive migrating motor complex in normals and in cholecystectomy patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Plasma clearance of oral and intravenous cholic acid in subjects with and without chronic liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Ursodeoxycholic acid oral tolerance test in patients with constitutional hyperbilirubinemias and effect of phenobarbital.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis. Part II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Physiological pharmacokinetics: an in vivo approach to membrane transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

The medical treatment of gallstones: a clinical application of the new biology of bile acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Kinetics and pool size of primary bile acids in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Metabolism of steroid and amino acid moieties of conjugated bile acids in man. II. Glycine-conjugated dihydroxy bile acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Metabolism of steroid and amino acid moieties of conjugated bile acids in man. I. Cholylglycine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

The preparation and properties of an antiserum for the radioimmunoassay of serum conjugated cholic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Dynamics of the enterohepatic circulation of bile acids. Postprandial serum concentrations of conjugates of cholic acid in health, cholecystectomized patients, and patients with bile acid malabsorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Radioimmunoassay of conjugated cholyl bile acids in serum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Postprandial concentrations of free and conjugated bile acids down the length of the normal human small intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Cholesterol solubility in bile. Evidence that supersaturated bile is frequent in healthy man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

The contribution of the colon to electrolyte and water conservation in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Metabolism of steroid and amino acid moieties of conjugated bile acids in man. 3. Cholyltaurine (taurocholic acid)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Metabolsim of steroid and amino acid moieties of conjugated bile acids in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Metabolism of lethocholate in healthy man. I. Biotransformation and biliary excretion of intravenously administered lithocholate, lithocholylglycine, and their sulfates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Plasma disappearance of radioactivity after intravenous injection of labeled bile acids in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Structural analysis of compartmental models for the hepatic kinetics of drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Sulfation and renal excretion of bile salts in patients with cirrhosis of the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Sulphated and unsulphated bile acids in serum, bile, and urine of patients with cholestasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Kinetics of [14C]cholic acid in fulminant hepatic failure: a prognostic test

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Individual bile acids in portal venous and systemic blood serum of fasting man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Radioimmunoassay of bile acids: development, validation, and preliminary application of an assay for conjugates of chenodeoxycholic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Metabolism of steroid and amino acid moieties of conjugated bile acids in man. V. Equations for the perturbed enterohepatic circulation and their application.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Biliary lipid output during three meals and an overnight fast. I. Relationship to bile acid pool size and cholesterol saturation of bile in gallstone and control subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Kinetics of 14C-glycocholic acid clearance in normal man and in patients with liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Hepatic transport kinetics and plasma disappearance curves: distributed modeling versus conventional approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Nocturnal gallbladder storage and emptying in gallstone patients and healthy subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Determinants of fasting and postprandial serum bile acid levels in healthy man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Bile acids measured in serum during fasting as a test for liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Physiological factors influencing serum bile acid levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Diurnal serum levels of primary conjugated bile acids : Assessment by specific radioimmunoassays for conjugates of cholic and chenodeoxycholic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Drug elimination interactions: analysis using a mathematical model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Colonic absorption of unconjugated bile acids: perfusion studies in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Hepatic extraction of bile salts in conscious dogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Hepatic taurine concentration and dietary taurine as regulators of bile acid conjugation with taurine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

The enterohepatic circulation of conjugated bile acids in healthy man: quantitative description and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

13 July 2018

Serum bile acid response to a test meal stimulus: a sensitive test of ileal function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

26 September 2018

Diurnal changes in serum unconjugated bile acids in normal man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

26 September 2018

Relationship of motility to flow of contents in the human small intestine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

26 September 2018

Enteric transport of chlordecone (Kepone®) in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

26 September 2018

Thiopental Pharmacokinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

26 September 2018

Determination of bile acids in needle biopsies of human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

26 September 2018

Pharmacokinetics of 1-beta-D-arabinofuranosylcytosine (ARA-C) deamination in several species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436958

26 September 2018

The extent of reflux of unconjugated 14C-cholic acid from the liver in subjects with normal liver function

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The turnover of cholic acid in man: bile acids and steroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Formation of Deoxycholic Acid and Chenodeoxycholic Acid in Man

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulfated and nonsulfated bile acids in urine, serum, and bile of patients with hepatobiliary diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic modeling of the dogfish shark (Squalus acanthias): distribution and urinary and biliary excretion of phenol red and its glucuronide

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development, validation, and application of a single-tube radioimmunoassay for cholic and chenodeoxycholic conjugated bile acids in human serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daily and hourly kinetics of the transformation of cholesterol-26-C14 into bile acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the Perfusion Technique for Colonic Absorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disturbances in fat digestion induced by acidic jejunal pH due to gastric hypersecretion in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gallbladder inertia and sluggish enterohepatic circulation of bile-salts in coeliac disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate Pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A physiological method for estimation of hepatic secretion of biliary lipids in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The formation of bile acids in patients with three types of hyperlipoproteinaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taurocholate metabolism in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of bile acids and microflora in the human small intestine. I. Bile acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered drug metabolism and elevated serum bile acids in liver disease: a unified pharmacokinetic explanation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical evaluation of real-time ultrasonography for the study of gallbladder volume and contraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of hepatic blood flow on taurocholate extraction by the isolated perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors in the mechanism of diarrhea in bile acid malabsorption: fecal pH--a key determinant

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fecal bile acid analysis in healthy japanese subjects using a lipophilic anion exchanger, capillary column gas chromatography and mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New results on saturation phenomena in BSP metabolism: the role of free and conjugated BSP

1 reference

https://pubmed.ncbi.nlm.nih.gov/6682120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI110828

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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