(Q35206959)

7 August 2017

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title

The human formyl peptide receptor as model system for constitutively active G-protein-coupled receptors (English)

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G protein-coupled receptor

7 August 2017

main subject

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author name string

Roland Seifert

series ordinal

1

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7 August 2017

Katharina Wenzel-Seifert

series ordinal

2

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7 August 2017

language of work or name

English

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publication date

1 September 2003

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7 August 2017

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7 August 2017

volume

73

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7 August 2017

issue

18

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7 August 2017

page(s)

2263-2280

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Broad immunocytochemical localization of the formylpeptide receptor in human organs, tissues, and cells.

7 August 2017

cites work

1 reference

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A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-protein coupling.

7 January 2021

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Receptor-effector coupling by G proteins

7 January 2021

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Molecular tinkering of G protein-coupled receptors: an evolutionary success

7 January 2021

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Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor

7 January 2021

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The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors

7 January 2021

1 reference

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Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human leukemic (HL-60) cells

7 January 2021

1 reference

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Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins

7 January 2021

1 reference

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Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits

7 January 2021

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Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils

7 January 2021

1 reference

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Regulatory effects of deoxycholic acid, a component of the anti-inflammatory traditional Chinese medicine Niuhuang, on human leukocyte response to chemoattractants

7 January 2021

1 reference

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Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors

7 January 2021

1 reference

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Reconstitution and characterization of the human neutrophil N-formyl peptide receptor and GTP binding proteins in phospholipid vesicles

7 January 2021

1 reference

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Inverse agonism at heptahelical receptors: concept, experimental approach and therapeutic potential

7 January 2021

1 reference

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C- and N-terminal residue effect on peptide derivatives' antagonism toward the formyl-peptide receptor

7 January 2021

1 reference

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Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine

7 January 2021

1 reference

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The acute inflammatory response and the role of phagocytic cells in periodontal health and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Selective inhibition of N-formylpeptide-induced neutrophil activation by carbamate-modified peptide analogues

7 January 2021

1 reference

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Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor

7 January 2021

1 reference

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C5A anaphylatoxin and its seven transmembrane-segment receptor

7 January 2021

1 reference

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Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

7 January 2021

1 reference

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Fluorescent labeling of purified beta 2 adrenergic receptor. Evidence for ligand-specific conformational changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Na+ regulation of formyl peptide receptor-mediated signal transduction in HL 60 cells. Evidence that the cation prevents activation of the G-protein by unoccupied receptors

7 January 2021

1 reference

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Dual Mg2+ control of formyl-peptide-receptor--G-protein interaction in HL 60 cells. Evidence that the low-agonist-affinity receptor interacts with and activates the G-protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Signal amplification in HL-60 granulocytes. Evidence that the chemotactic peptide receptor catalytically activates guanine-nucleotide-binding regulatory proteins in native plasma membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

G proteins: transducers of receptor-generated signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

In vivo reconstitution of dopamine D2S receptor-mediated G protein activation in baculovirus-infected insect cells: preferred coupling to Gi1 versus Gi2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Single nucleotide polymorphisms of the N-formyl peptide receptor in localized juvenile periodontitis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Agonist-independent effects of muscarinic antagonists on Ca2+ and K+ currents in frog and rat cardiac cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

The human histamine H2-receptor couples more efficiently to Sf9 insect cell Gs-proteins than to insect cell Gq-proteins: limitations of Sf9 cells for the analysis of receptor/Gq-protein coupling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Chemoattractant receptor-specific differences in G protein activation rates regulate effector enzyme and functional responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Constitutive activity of human prostaglandin E receptor EP3 isoforms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

G-protein-coupled receptors in HL-60 human leukemia cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Differential activation of dibutyryl cAMP-differentiated HL-60 human leukemia cells by chemoattractants.

7 January 2021

1 reference

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CCK receptor polymorphisms: an illustration of emerging themes in pharmacogenomics

7 January 2021

1 reference

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Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Formyl-peptide receptors revisited

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Receptors for chemotactic formyl peptides as pharmacological targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

The two-state model of receptor activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

7 January 2021

1 reference

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G proteins endogenously expressed in Sf 9 cells: interactions with mammalian histamine receptors

7 January 2021

1 reference

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Gbetagamma stimulates phosphoinositide 3-kinase-gamma by direct interaction with two domains of the catalytic p110 subunit.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

The olfactory G protein G(alphaolf) possesses a lower GDP-affinity and deactivates more rapidly than G(salphashort): consequences for receptor-coupling and adenylyl cyclase activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Cyclosporins: structure-activity relationships for the inhibition of the human FPR1 formylpeptide receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Activation of calcium currents in cardiac myocytes by empty beta-adrenoceptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

The molecular biology of leukocyte chemoattractant receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Sequence and organization of the human N-formyl peptide receptor-encoding gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Detection of multiple forms of Gi alpha in HL60 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Review: amino acid domains involved in constitutive activation of G-protein-coupled receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

The N-formyl peptide receptor: a model for the study of chemoattractant receptor structure and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Virally encoded 7TM receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Constitutively active G protein-coupled receptors: potential mechanisms of receptor activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

N-formylmethionyl peptides as chemoattractants for leucocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Defective Gi protein coupling in two formyl peptide receptor mutants associated with localized juvenile periodontitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Reconstitution of beta2-adrenoceptor-GTP-binding-protein interaction in Sf9 cells--high coupling efficiency in a beta2-adrenoceptor-G(s alpha) fusion protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The Beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Platelet-activating factor receptor and signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Inhibition by pertussis toxin of the activation of Na+-dependent uridine transport in dimethyl-sulphoxide-induced HL-60 leukaemia cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Complexity and diversity of mammalian adenylyl cyclases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Inverse agonist activities of beta-adrenoceptor antagonists in rat myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Molecular analysis of beta(2)-adrenoceptor coupling to G(s)-, G(i)-, and G(q)-proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Functional differences between human formyl peptide receptor isoforms 26, 98, and G6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Critical role of N-terminal N-glycosylation for proper folding of the human formyl peptide receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

High constitutive activity of the human formyl peptide receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Quantitative analysis of formyl peptide receptor coupling to g(i)alpha(1), g(i)alpha(2), and g(i)alpha(3).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Role of GDP in formyl-peptide-receptor-induced activation of guanine-nucleotide-binding proteins in membranes of HL 60 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Inhibitory effects of spinorphin, a novel endogenous regulator, on chemotaxis, O2- generation, and exocytosis by N-formylmethionyl-leucyl-phenylalanine (FMLP)-stimulated neutrophils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

Specificity and complexity of receptor-G-protein interaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Regulation of the superoxide-forming NADPH oxidase of human neutrophils is not altered in essential hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

inferred from DOI database lookup

7 January 2021

based on heuristic

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900654-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0024-3205(03)00654-4

1 reference

7 August 2017

1 reference