(Q35207978)

7 August 2017

title

Aggregation kinetics of interrupted polyglutamine peptides (English)

1 reference

7 August 2017

Robert H Walters

1

1 reference

7 August 2017

Regina M Murphy

series ordinal

2

1 reference

7 August 2017

language of work or name

English

0 references

publication date

29 July 2011

1 reference

Journal of Molecular Biology

7 August 2017

published in

1 reference

7 August 2017

volume

412

1 reference

7 August 2017

issue

3

1 reference

7 August 2017

page(s)

505-519

1 reference

Assessing the contribution of heterogeneous distributions of oligomers to aggregation mechanisms of polyglutamine peptides

7 August 2017

cites work

1 reference

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13 July 2018

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13 July 2018

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Examining polyglutamine peptide length: a connection between collapsed conformations and increased aggregation

13 July 2018

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13 July 2018

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Single homopolypeptide chains collapse into mechanically rigid conformations

13 July 2018

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13 July 2018

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13 July 2018

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Model discrimination and mechanistic interpretation of kinetic data in protein aggregation studies

13 July 2018

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Normal aging modulates the neurotoxicity of mutant huntingtin

13 July 2018

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Atomistic simulations of the effects of polyglutamine chain length and solvent quality on conformational equilibria and spontaneous homodimerization

13 July 2018

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Polyglutamine neurodegeneration: protein misfolding revisited.

13 July 2018

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Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic

13 July 2018

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A 10-A spectroscopic ruler applied to short polyprolines

13 July 2018

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Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions

13 July 2018

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Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins

13 July 2018

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polyglutamine aggregation nucleation: thermodynamics of a highly unfavorable protein folding reaction

13 July 2018

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13 July 2018

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

13 July 2018

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Conformation of prion protein repeat peptides probed by FRET measurements and molecular dynamics simulations

13 July 2018

1 reference

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Huntingtin aggregation and toxicity in Huntington's disease

13 July 2018

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Mutational analysis of the structural organization of polyglutamine aggregates

13 July 2018

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Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

13 July 2018

1 reference

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Amyloid fibers are water-filled nanotubes

13 July 2018

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Beyond the Qs in the polyglutamine diseases

13 July 2018

1 reference

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Solubilization and disaggregation of polyglutamine peptides

13 July 2018

1 reference

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Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease

13 July 2018

1 reference

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Protein aggregation and pathogenesis of Huntington's disease: mechanisms and correlations

13 July 2018

1 reference

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Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

13 July 2018

1 reference

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Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease

13 July 2018

1 reference

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Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides.

13 July 2018

1 reference

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Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases

13 July 2018

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13 July 2018

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N-terminal polyglutamine-containing fragments inhibit androgen receptor transactivation function

13 July 2018

1 reference

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The intrinsic stiffness of polyglutamine peptides

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Reconsidering the mechanism of polyglutamine peptide aggregation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Structural and functional analysis of ataxin-2 and ataxin-3.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Neurodegeneration. A glutamine-rich trail leads to transcription factors

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Amyloid-like features of polyglutamine aggregates and their assembly kinetics

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Pathogenic and Non-pathogenic Polyglutamine Tracts Have Similar Structural Properties: Towards a Length-dependent Toxicity Gradient

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170924

Interaction of alpha-dansylated peptide inhibitors with porcine pepsin: detection of complex formation by fluorescence energy transfer and chromatography and evidence for a two-step binding scheme

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21821045

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An accurate model of polyglutamine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21821045

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A toxic monomeric conformer of the polyglutamine protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21821045

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JMB.2011.07.003

1 reference

7 August 2017

1 reference

7 August 2017

1 reference