(Q35208979)

7 August 2017

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title

Xenobiotic bioconversion in human epidermis models (English)

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7 August 2017

Audra L Stinchcomb

1

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7 August 2017

publication date

1 August 2003

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7 August 2017

published in

Pharmaceutical Research

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7 August 2017

volume

20

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7 August 2017

issue

8

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7 August 2017

page(s)

1113-1118

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Harmful effects of UVA on the structure and barrier function of engineered human cutaneous tissues

7 August 2017

cites work

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12 December 2020

Evaluation of a human bio-engineered skin equivalent for drug permeation studies

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12 December 2020

Cytotoxicity of wound dressing materials assessed using cultured skin equivalents

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12 December 2020

Epidermal morphogenesis and induction of the 67 kD keratin polypeptide by culture of human keratinocytes at the liquid-air interface

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12 December 2020

Modeling of diffusion and concurrent metabolism in cutaneous tissue

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12 December 2020

Efficient in vitro transduction of epithelial cells and keratinocytes with improved adenoviral gene transfer for the application in skin tissue engineering

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12 December 2020

Development of a bilayered living skin construct for clinical applications

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12 December 2020

Reconstituted epidermis: a novel model for the study of drug metabolism in human epidermis.

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12 December 2020

Constitutive and inducible expression of drug metabolizing enzymes in cultured human keratinocytes

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12 December 2020

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12 December 2020

Cutaneous metabolism of nitroglycerin in vitro. I. Homogenized versus intact skin

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12 December 2020

Physical characterization of the stratum corneum of an in vitro human skin equivalent produced by tissue engineering and its comparison with normal human skin by ATR-FTIR spectroscopy and thermal analysis (DSC)

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12 December 2020

Cultured keratinocytes in in vitro dermatotoxicological investigation: a review.

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12 December 2020

The antipsoriatic drug metabolite etretin (Ro 10-1670) alters the metabolism of fatty acids in human keratinocytes in culture

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12 December 2020

Methods for the Serum-Free Culture of Keratinocytes and Transplantation of Collagen-GAG-Based Skin Substitutes

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12 December 2020

Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo

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12 December 2020

Comparison of human skin or epidermis models with human and animal skin in in-vitro percutaneous absorption

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12 December 2020

Repeated exposures of human skin equivalent to low doses of ultraviolet-B radiation lead to changes in cellular functions and accumulation of cyclobutane pyrimidine dimers

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12 December 2020

Invasion of Candida albicans correlates with expression of secreted aspartic proteinases during experimental infection of human epidermis

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12 December 2020

UVB-induced conversion of 7-dehydrocholesterol to 1alpha,25-dihydroxyvitamin D3 in an in vitro human skin equivalent model

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12 December 2020

The metabolism of a series of ester pro-drugs by NCTC 2544 cells, skin homogenate and LDE testskin

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12 December 2020

A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels

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12 December 2020

Barrier function in reconstructed epidermis and its resemblance to native human skin

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12 December 2020

Conversion of vitamin D3 to 1alpha,25-dihydroxyvitamin D3 in human skin equivalents

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12 December 2020

Keratinocytes and fibroblasts in a human skin equivalent model enhance melanocyte survival and melanin synthesis after ultraviolet irradiation.

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12 December 2020

Selective peroxidation and externalization of phosphatidylserine in normal human epidermal keratinocytes during oxidative stress induced by cumene hydroperoxide

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12 December 2020

The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C

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12 December 2020

Cell proliferation and differentiation in a model of human skin equivalent

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12 December 2020

Topical hyaluronidase decreases hyaluronic acid and CD44 in human skin and in reconstituted human epidermis: evidence that hyaluronidase can permeate the stratum corneum

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12 December 2020

Expression of multiple cytochrome p450 enzymes and multidrug resistance-associated transport proteins in human skin keratinocytes

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12 December 2020

Cytokine expression induced by Candida albicans in a model of cutaneous candidosis based on reconstituted human epidermis

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12 December 2020

Expression of type 1 5alpha-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic(R)): a new model for screening skin-targeted androgen modulators

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12 December 2020

Stratum corneum lipids of human epidermal keratinocyte air-liquid cultures: implications for barrier function

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12 December 2020

An approach for development of alternative test methods based on mechanisms of skin irritation

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12 December 2020

Reconstituted 3-dimensional human skin as a novel in vitro model for studies of carcinogenesis

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12 December 2020

Expression of vitamin D3 25-hydroxylase (CYP27) mRNA after induction by vitamin D3 or UVB radiation in keratinocytes of human skin equivalents--a preliminary study

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12 December 2020

UV-irradiation depletes antioxidants and causes oxidative damage in a model of human skin.

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12 December 2020

Culture and drug biotransformation capacity of adult human keratinocytes from post-mortem skin

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12 December 2020

Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells

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12 December 2020

An improved and rapid method to construct skin equivalents from human hair follicles and fibroblasts

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12 December 2020

Biosynthesis of 3,4-didehydroretinol from retinol by human skin keratinocytes in culture

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12 December 2020

Uptake and metabolism of cyclosporin a and SDZ IMM 125 in the human in vitro skin2TM dermal and barrier function models

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12 December 2020

The influence of the response of skin equivalent systems to topically applied consumer products by epithelial--mesenchymal interactions

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12 December 2020

Differential expression of the efflux pumps P-glycoprotein and multidrug resistance-associated protein in human monocyte-derived dendritic cells.

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12 December 2020

Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation

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12 December 2020

Overview of in vitro cell culture technologies and pharmaco-toxicological applications

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12 December 2020

The human keratinocyte cell line HaCaT: an in vitro cell culture model for keratinocyte testosterone metabolism

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12 December 2020

Peroxisome proliferator-activated receptor-alpha enhances lipid metabolism in a skin equivalent model

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12 December 2020

Effect of skin barrier competence on SLS and water-induced IL-1alpha expression

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12 December 2020

Terminal Epidermal Differentiation of Human Keratinocytes Grown in Chemically Defined Medium on Inert Filter Substrates at the Air-Liquid Interface

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12 December 2020

Functional evaluation of anchored skin equivalent cultured in vitro: percutaneous absorption studies and lipid analysis

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12 December 2020

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

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12 December 2020

The metabolism of 7-ethoxycoumarin and 7-hydroxycoumarin by rat and hairless mouse skin strips

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12 December 2020

In Vitro expression of drug metabolizing enzyme activities in human adult keratinocytes under various culture conditions and their response to inducers

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12 December 2020

Epidermal aminopeptidase activity and metabolism as observed in an organized HaCaT cell sheet model

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12 December 2020

Identifiers

DOI

10.1023/A:1025024309223

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7 August 2017

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