(Q35209840)

7 August 2017

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title

Potential chemotherapeutic targets in the purine metabolism of parasites (English)

1 reference

7 August 2017

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Mahmoud H el Kouni

1

1 reference

7 August 2017

publication date

1 September 2003

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Pharmacology & Therapeutics

7 August 2017

published in

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7 August 2017

volume

99

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7 August 2017

issue

3

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7 August 2017

page(s)

283-309

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Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma brucei

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Molecular characterization and overexpression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purification and characterization of the adenine phosphoribosyltransferase and hypoxanthine-guanine phosphoribosyltransferase activities from Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase from Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Cloning and expression of the adenine phosphoribosyltransferase gene from Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Uptake of Nitrobenzylthioinosine and Purine β- l -Nucleosides by Intracellular Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

A Leishmania major nucleobase transporter responsible for allopurinol uptake is a functional homolog of the Trypanosoma brucei H2 transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Rational design of selective submicromolar inhibitors of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Virtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Two high affinity nucleoside transporters in Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Trypanosoma cruzi: allopurinol in the treatment of mice with experimental acute Chagas disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Trypanosoma cruzi: 4-aminopyrazolopyrimidine in the treatment of experimental Chagas' disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Polyamine metabolism: a potential therapeutic target in trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside Transporters in Leishmania Major: Diversity in Adenosine Transporter Expression or Function in Different Strains

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Kinetic mechanism of adenine phosphoribosyltransferase from Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Successful treatment of cutaneous leishmaniasis with allopurinol after failure of treatment with ketoconazole

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine nucleoside and nucleobase cell membrane transport in Giardia lamblia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

The hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus has unique properties

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Adenosine analog metabolism in Giardia lamblia. Implications for chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Efficacy of pyrazolopyrimidine ribonucleosides against Trypanosoma cruzi: studies in vitro and in vivo with sensitive and resistant strains.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Leishmania donovani: oral efficacy and toxicity of formycin B in the infected hamster

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Reaction kinetics and inhibition of adenosine kinase from Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Active site thiol(s) in Leishmania donovani adenosine kinase: comparison with hamster enzyme and evidence for the absence of regulatory adenosine binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Phosphorylation and anti-leishmanial activity of formycin B

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Arsenical-resistant trypanosomes lack an unusual adenosine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

A drug resistance determinant in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Isolation and functional characterization of the PfNT1 nucleoside transporter gene from Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Cloning of a novel inosine-guanosine transporter gene from Leishmania donovani by functional rescue of a transport-deficient mutant.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside transporters of parasitic protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside transporters of mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

The adenosine transporter of Toxoplasma gondii. Identification by insertional mutagenesis, cloning, and recombinant expression

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Isolation, sequencing and expression of the gene encoding hypoxanthine-guanine-xanthine phosphoribosyltransferase of Tritrichomonas foetus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Crystal structure of adenosine kinase from Toxoplasma gondii at 1.8 Å resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

High level expression in Escherichia coli of soluble, enzymatically active schistosomal hypoxanthine/guanine phosphoribosyltransferase and trypanosomal ornithine decarboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

A nonspecific nucleoside hydrolase from Leishmania donovani: implications for purine salvage by the parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Recombinant expression, purification, and characterization of Toxoplasma gondii adenosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Characterization of nucleoside uptake and transport in Entamoeba histolytica

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Identification of a broad-specificity nucleoside transporter with affinity for the sugar moiety in Giardia intestinalis trophozoites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Studies on several pyrrolo[2,3-d]pyrimidine analogues of adenosine which lack significant agonist activity at A1 and A2 receptors but have potent pharmacological activity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Hypoxanthine uptake through a purine-selective nucleobase transporter in Trypanosoma brucei brucei procyclic cells is driven by protonmotive force

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine nucleobase transport in bloodstream forms of Trypanosoma brucei brucei is mediated by two novel transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Characterization of a Nucleoside/Proton Symporter in ProcyclicTrypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Further evidence for a link between melarsoprol resistance and P2 transporter function in African trypanosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Differential regulation of nucleoside and nucleobase transporters in Crithidia fasciculata and Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Partial purification and properties of a nucleoside hydrolase from Crithidia.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine salvage in Schistosoma mansoni schistosomules

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Efficacy of combination therapy with tubercidin and nitrobenzylthioinosine 5'-monophosphate against chronic and advanced stages of schistosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Metabolism of adenosine analogues by Schistosoma mansoni and the effect of nucleoside transport inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Combination therapy of schistosomiasis by tubercidin and nitrobenzylthioinosine 5'-monophosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Combination therapy of Schistosoma japonicum by tubercidin and nitrobenzylthioinosine 5'-monophosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Treatment of schistosomiasis by purine nucleoside analogues in combination with nucleoside transport inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Prevention of tubercidin host toxicity by nitrobenzylthioinosine 5'-monophosphate for the treatment of schistosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

A low-affinity nucleobase transporter in the protozoan parasite Giardia intestinalis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in Trypanosoma brucei gambiense

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in the bloodstream forms of Trypanosoma gambiense and Trypanosoma rhodesiense

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Exploitation of methylthioribose kinase in the development of antiprotozoal drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Assessment of Leishmania promastigote growth in vitro by means of nucleoside hydrolase activity determination

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside permeation in mouse erythrocytes infected with Plasmodium yoelii

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nutrient transport pathways in Plasmodium-infected erythrocytes: what and where are they?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Stage-specific alteration of nucleoside membrane permeability and nitrobenzylthioinosine insensitivity in Plasmodium falciparum infected erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Antimalarial action of nitrobenzylthioinosine in combination with purine nucleoside antimetabolites.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Substrate specificities of 5'-deoxy-5'-methylthioadenosine phosphorylase from Trypanosoma brucei brucei and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Stage-specific development of a novel adenosine transporter in Leishmania donovani amastigotes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside and nucleobase transport systems of mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Enzymes of purine salvage in Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine and pyrimidine metabolism in the Trypanosomatidae

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

The specificity of purine base and nucleoside uptake in promastigotes of Leishmania braziliensis panamensis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside uptake by Trichomonas vaginalis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine-metabolising enzymes in Entamoeba histolytica

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine-metabolizing enzymes in Babesia divergens

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine base transport in wild-type and mycophenolic acid-resistant Tritrichomonas foetus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in Trichomonas vaginalis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Carbocyclic inosine as a potent anti-leishmanial agent: the metabolism and selective cytotoxic effects of carbocyclic inosine in promastigotes of Leishmania tropica and Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Genetic analysis of purine metabolism in Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Structure-activity relationship for the binding of nucleoside ligands to adenosine kinase from Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Characterization of a mutant Leishmania donovani deficient in adenosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside analogs as antiparasitic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Uptake of purine bases and nucleosides in African trypanosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Xanthine phosphoribosyltransferase from Leishmania donovani. Molecular cloning, biochemical characterization, and genetic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Allopurinol in the treatment of visceral leishmaniasis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Differential inhibitory effects of GMP-2',3'-dialdehyde on human and schistosomal hypoxanthine-guanine phosphoribosyltransferases.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Identification of the Active Sites of Human and Schistosomal Hypoxanthine-Guanine Phosphoribosyltransferases by GMP-2',3'-dialdehyde Affinity Labeling

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Probing the active site of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase using covalent modification of cysteine residues

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Inactivation of Tritrichomonas foetus and Schistosoma mansoni purine phosphoribosyltransferases by arginine-specific reagents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purification and characterization of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase and comparison with the human enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Membrane transport of nucleobases: interaction with inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in the intact sporozoites and merozoites of Eimeria tenella

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Molecular genetics of nucleoside transporters in Leishmania and African trypanosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

A membrane network for nutrient import in red cells infected with the malaria parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine and pyrimidine transport in Schistosoma mansoni

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine salvage in Entamoeba histolytica

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

The Partial Purification and Characterization of Adenosine Kinase from Entamoeba histolytica *

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Therapy of visceral leishmaniasis in renal transplant recipients intolerant to pentavalent antimonials

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in Leishmania donovani amastigotes and promastigotes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Potent in vivo activity of arprinocid, a purine analogue, against murine toxoplasmosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Pyrazolopyrimidine metabolism in Leishmania and Trypanosomes: Significant differences between host and parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Pyrazolopyrimidine metabolism in the pathogenic trypanosomatidae

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in Leishmania donovani and Leishmania braziliensis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Allopurinol in the Treatment of American Cutaneous Leishmaniasis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

A nucleoside transporter from Trypanosoma brucei involved in drug resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Identification and characterization of trypanocides by functional expression of an adenosine transporter from Trypanosoma brucei in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine salvage and metabolism inBabesia bovis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

MEMBRANE TRANSPORT OF PURINES AND PYRIMIDINES IN A CESTODE

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine and pyrimidine metabolizing activities in Trichomonas vaginalis extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purification, characterization, substrate and inhibitor specificity of adenosine kinase from several Eimeria species

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Trypanosoma cruzi adenine nucleoside phosphorylase. Purification and substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Treatment of cutaneous leishmaniasis with a combination of allopurinol and low-dose meglumine antimoniate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Leishmania donovani: pilot study for evaluation of therapeutic effects of inosine analogs against amastigotes in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Converting the guanine phosphoribosyltransferase from Giardia lamblia to a hypoxanthine-guanine phosphoribosyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

The pivotal role of guanine phosphoribosyltransferase in purine salvage by Giardia lamblia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside transport in parasites--current status and methodological aspects

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Comparative aspects of purine metabolism in some African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Leishmania donovani: characteristics of adenosine and inosine transporters in promastigotes of two different strains

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Isozyme-specific transition state inhibitors for the trypanosomal nucleoside hydrolases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Incorporation of Precursors into Toxoplasma DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Toxoplasma gondii: characterization of a mutant resistant to 6-thioxanthine.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Arabinosyl nucleosides inhibit Toxoplasma gondii and allow the selection of resistant mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Toxoplasma gondii: mechanism of the parasitostatic action of 6-thioxanthine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Understanding substrate specificity in human and parasite phosphoribosyltransferases through calculation and experiment

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Plasmodium falciparum: expression of the adenine phosphoribosyltransferase gene in mouse L cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Direct access to serum macromolecules by intraerythrocytic malaria parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Properties and substrate specificity of a purine phosphoribosyltransferase from the human malaria parasite, Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Localization of the Plasmodium falciparum PfNT1 nucleoside transporter to the parasite plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Toxoplasma gondii adenosine kinase: expression, purification, characterization, crystallization and preliminary crystallographic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Methionine recycling as a target for antiprotozoal drug development

1 reference

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7 January 2021

Treatment of American cutaneous leishmaniasis with orally administered allopurinol riboside

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

The adenine phosphoribosyltransferase from Giardia lamblia has a unique reaction mechanism and unusual substrate binding properties

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

OBSERVATIONS ON THE METABOLISM OF 5'-METHYLTHIOADENOSINE

1 reference

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7 January 2021

Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop

1 reference

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7 January 2021

Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding 1 1Edited by I. A. Wilson

1 reference

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7 January 2021

The parasitophorous vacuole membrane surrounding intracellular Toxoplasma gondii functions as a molecular sieve

1 reference

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7 January 2021

Toxoplasma gondii tachyzoites possess an unusual plasma membrane adenosine transporter

1 reference

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7 January 2021

Toxoplasma gondii: purine synthesis and salvage in mutant host cells and parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in the schistosomes: potential targets for chemotherapy

1 reference

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7 January 2021

5-Methylthioribose as a precursor of the carbon chain of methionine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Conversion of 5'-methylthioadenosine into S-adenosylmethionine by yeast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-å crystal structure

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Molecular cloning and expression of adenosine kinase from Leishmania donovani: identification of unconventional P-loop motif

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Cloning, expression and characterization of an unusual guanine phosphoribosyltransferase from Giardia lamblia

1 reference

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7 January 2021

Rational design of novel antimicrobials: blocking purine salvage in a parasitic protozoan

1 reference

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7 January 2021

Studies on metabolic role of 5'-Methylthioadenosine in Ochromonas malhamensis and other microorganisms

1 reference

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7 January 2021

Evidence for multiple active states of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase

1 reference

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7 January 2021

Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes

1 reference

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7 January 2021

Insertional tagging of at least two loci associated with resistance to adenine arabinoside in Toxoplasma gondii, and cloning of the adenosine kinase locus.

1 reference

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7 January 2021

A novel parasite-derived suicide gene for cancer gene therapy with specificity for lung cancer cells

1 reference

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7 January 2021

Parasite-induced permeation of nucleosides in Plasmodium falciparum malaria

1 reference

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7 January 2021

Specific treatment of Chagas disease: current status and new developments

1 reference

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7 January 2021

Cloning and expression in Escherichia coli of a hypoxanthine-guanine phosphoribosyltransferase-encoding cDNA from Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Cloning of Leishmania nucleoside transporter genes by rescue of a transport-deficient mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Point mutations in a nucleoside transporter gene from Leishmania donovani confer drug resistance and alter substrate selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax

1 reference

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7 January 2021

Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax

1 reference

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7 January 2021

Different substrate recognition motifs of human and trypanosome nucleobase transporters. Selective uptake of purine antimetabolites

1 reference

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7 January 2021

Effectiveness of Allopurinol against Leishmania Braziliensis Panamensis in Aotus Trivirgatus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine salvage networks in Giardia lamblia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine metabolism in the protozoan parasite Eimeria tenella

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Recycling of 5'-methylthioadenosine-ribose carbon atoms into methionine in tomato tissue in relation to ethylene production

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Purine salvage by Tritrichomonas foetus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Pathways of purine ribonucleotide biosynthesis in the adult worm Metastrongylus apri (nematoda: Metastronglyloidea) from pig lung

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Comparing the human and schistosomal hypoxanthine-guanine phosphoribosyltransferases by circular dichroism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

Methionine synthesis from 3-methylthioribose in apple tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2803%2900071-8

7 January 2021

10.1016/S0163-7258(03)00071-8

Identifiers

DOI

1 reference

7 August 2017

1 reference