(Q35212539)

7 August 2017

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title

Iron chelators and iron toxicity (English)

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7 August 2017

Gary M Brittenham

1

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7 August 2017

publication date

1 June 2003

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7 August 2017

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7 August 2017

volume

30

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7 August 2017

issue

2

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7 August 2017

page(s)

151-158

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Iron overload in viral and alcoholic liver disease

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Is there a threshold of hepatic iron concentration that leads to cirrhosis in C282Y hemochromatosis?

1 reference

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7 January 2021

Chemistry and biology of eukaryotic iron metabolism

1 reference

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7 January 2021

Effects of iron overload and hepatitis C virus positivity in determining progression of liver fibrosis in thalassemia following bone marrow transplantation.

1 reference

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7 January 2021

Desferrithiocin is an effective iron chelator in vivo and in vitro but ferrithiocin is toxic

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Toxicity of oral iron chelator L1

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7 January 2021

The desferrithiocin pharmacophore

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7 January 2021

HBED ligand: preclinical studies of a potential alternative to deferoxamine for treatment of chronic iron overload and acute iron poisoning

1 reference

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7 January 2021

Evaluation of desferrithiocin and its synthetic analogues as orally effective iron chelators

1 reference

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7 January 2021

Effects of C-4 stereochemistry and C-4' hydroxylation on the iron clearing efficiency and toxicity of desferrithiocin analogues

1 reference

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7 January 2021

Desazadesmethyldesferrithiocin analogues as orally effective iron chelators

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7 January 2021

An investigation of desferrithiocin metabolism.

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7 January 2021

Survival and disease complications in thalassemia major.

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7 January 2021

Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major

1 reference

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7 January 2021

Hepatic iron stores and markers of iron overload in alcoholics and patients with idiopathic hemochromatosis

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7 January 2021

Safety profile of the oral iron chelator deferiprone: a multicentre study

1 reference

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7 January 2021

C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

The action of nine chelators on iron-dependent radical damage

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Haptoglobin polymorphism and body iron stores

1 reference

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7 January 2021

Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations

1 reference

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7 January 2021

Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis

1 reference

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7 January 2021

Interrelationships of alcohol and iron in liver disease with particular reference to the iron-binding proteins, ferritin and transferrin

1 reference

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7 January 2021

Iron reduction before and during interferon therapy of chronic hepatitis C: results of a multicenter, randomized, controlled trial

1 reference

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7 January 2021

Liver iron is predictive of death in alcoholic cirrhosis: a multivariate study of 229 consecutive patients with alcoholic and/or hepatitis C virus cirrhosis: a prospective follow up study

1 reference

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7 January 2021

Results from a phase I clinical trial of HBED.

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Heterozygotes for HFE mutations have no increased risk of advanced alcoholic liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

ICL670A: a new synthetic oral chelator: evaluation in hypertransfused rats with selective radioiron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells in culture

1 reference

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7 January 2021

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

1 reference

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7 January 2021

Design of clinically useful iron(III)-selective chelators

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Long-term safety and effectiveness of iron-chelation therapy with deferiprone for thalassemia major

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Survival in medically treated patients with homozygous beta-thalassemia

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Spur cell anaemia and hepatic iron stores in patients with alcoholic liver disease undergoing orthotopic liver transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Deferoxamine pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Practical management of iron overload.

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

The toxic effects of desferrioxamine

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Changing concepts in haemochromatosis

1 reference

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7 January 2021

Risk factors of fibrosis in alcohol-induced liver disease

1 reference

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7 January 2021

The controversial role of deferiprone in the treatment of thalassemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Multifunctional antioxidant activity of HBED iron chelator

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Chronic hepatitis C treated with phlebotomy alone: biochemical and histological outcome

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Iron excretion in thalassaemia major after administration of chelating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Chelator-induced iron excretion in iron-overloaded marmosets

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

The role of cellular oxidases and catalytic iron in the pathogenesis of ethanol-induced liver injury

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Iron regulation of hepatic macrophage TNFalpha expression

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Experimental liver cirrhosis induced by alcohol and iron

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Lack of progressive hepatic fibrosis during long-term therapy with deferiprone in subjects with transfusion-dependent beta-thalassemia

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Long term effects of phlebotomy on biochemical and histological parameters of chronic hepatitis C

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

Survival and causes of death in thalassaemia major

1 reference

https://api.crossref.org/works/10.1016%2FS0741-8329%2803%2900101-0

7 January 2021

10.1016/S0741-8329(03)00101-0

Identifiers

DOI

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7 August 2017

1 reference