(Q35212757)

7 August 2017

title

BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1. (English)

1 reference

7 August 2017

Chunmin Ge

1

1 reference

7 August 2017

Lixiao Che

2

1 reference

7 August 2017

Jinyu Ren

3

1 reference

7 August 2017

Raj K Pandita

4

1 reference

7 August 2017

Jing Lu

5

1 reference

7 August 2017

Kaiyi Li

6

1 reference

7 August 2017

Tej K Pandita

7

1 reference

7 August 2017

Chunying Du

8

1 reference

7 August 2017

language of work or name

English

0 references

publication date

2 March 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

1 reference

7 August 2017

volume

112

1 reference

7 August 2017

issue

11

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7 August 2017

page(s)

E1210-9

1 reference

Emerging roles of MCPH1: expedition from primary microcephaly to cancer

7 August 2017

cites work

1 reference

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Repair of strand breaks by homologous recombination

13 July 2018

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BRIT1 regulates p53 stability and functions as a tumor suppressor in breast cancer.

13 July 2018

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Deubiquitylating enzymes and DNA damage response pathways

13 July 2018

1 reference

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Chromatin remodeling at DNA double-strand breaks

13 July 2018

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Regulation of DNA damage responses by ubiquitin and SUMO.

13 July 2018

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Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair

13 July 2018

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RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response.

13 July 2018

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BRCT domains: easy as one, two, three

13 July 2018

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Scaffold proteins: hubs for controlling the flow of cellular information

13 July 2018

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RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci

13 July 2018

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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

13 July 2018

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Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks

13 July 2018

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Regulation of homologous recombination by RNF20-dependent H2B ubiquitination.

13 July 2018

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WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription

13 July 2018

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The DNA Damage Response: Making It Safe to Play with Knives

13 July 2018

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Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Purified human BRCA2 stimulates RAD51-mediated recombination

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

BRIT1/MCPH1 links chromatin remodelling to DNA damage response.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Targeting the DNA damage response for cancer therapy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Histone ubiquitination associates with BRCA1-dependent DNA damage response

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

13 July 2018

IAPs: what's in a name?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

IAPs: more than just inhibitors of apoptosis proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Final stages of cytokinesis and midbody ring formation are controlled by BRUCE

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Distinct BRCT domains in Mcph1/Brit1 mediate ionizing radiation-induced focus formation and centrosomal localization.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Polyubiquitin chains: polymeric protein signals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

BRUCE, a giant E2/E3 ubiquitin ligase and inhibitor of apoptosis protein of the trans-Golgi network, is required for normal placenta development and mouse survival

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

A human IAP-family gene, apollon, expressed in human brain cancer cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

UBPY: a growth-regulated human ubiquitin isopeptidase.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

Genetic manipulation of genomes with rare-cutting endonucleases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371995

13 July 2018

Identifiers

DOI

10.1073/PNAS.1418335112

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference