(Q35214193)

7 August 2017

title

Shiga toxins induce autophagy leading to differential signalling pathways in toxin-sensitive and toxin-resistant human cells (English)

1 reference

7 August 2017

0 references

Moo-Seung Lee

1

1 reference

7 August 2017

Rama P Cherla

2

1 reference

7 August 2017

Matthew H Jenson

3

1 reference

7 August 2017

Dinorah Leyva-Illades

4

1 reference

7 August 2017

Margarita Martinez-Moczygemba

5

1 reference

7 August 2017

Vernon L Tesh

6

1 reference

7 August 2017

language of work or name

1 reference

4 July 2011

1 reference

7 August 2017

published in

Cellular Microbiology

1 reference

7 August 2017

volume

13

1 reference

7 August 2017

issue

10

1 reference

7 August 2017

page(s)

1479-1496

1 reference

Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

7 August 2017

cites work

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28 July 2018

Autophagy and metabolism

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The in vitro cleavage of the hAtg proteins by cell death proteases

28 July 2018

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Overview of macroautophagy regulation in mammalian cells

28 July 2018

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Signaling through C/EBP homologous protein and death receptor 5 and calpain activation differentially regulate THP-1 cell maturation-dependent apoptosis induced by Shiga toxin type 1

28 July 2018

1 reference

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Induction of apoptosis by Shiga toxins

28 July 2018

1 reference

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Shiga toxins--from cell biology to biomedical applications

28 July 2018

1 reference

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Endocytosis and retrograde transport of Shiga toxin.

28 July 2018

1 reference

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The MAP kinase-activated protein kinase 2 (MK2) contributes to the Shiga toxin-induced inflammatory response

28 July 2018

1 reference

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Bcl-2 regulates the onset of shiga toxin 1-induced apoptosis in THP-1 cells

28 July 2018

1 reference

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Shiga toxin receptor Gb3Cer/CD77: tumor-association and promising therapeutic target in pancreas and colon cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxin 1-induced proinflammatory cytokine production is regulated by the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death

28 July 2018

1 reference

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Autophagy: molecular machinery, regulation, and implications for renal pathophysiology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Fractalkine and CX3CR1 mediate leukocyte capture by endothelium in response to Shiga toxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes

28 July 2018

1 reference

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ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxin induces tubular membrane invaginations for its uptake into cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxin 1 induces apoptosis through the endoplasmic reticulum stress response in human monocytic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Self-eating and self-killing: crosstalk between autophagy and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Switch between apoptosis and autophagy: radiation-induced endoplasmic reticulum stress?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Autophagy and cell death.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Autophagy is activated for cell survival after endoplasmic reticulum stress

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Does autophagy contribute to cell death?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Silencing of Bak ameliorates apoptosis of human proximal tubular epithelial cells by Escherichia coli-derived Shiga toxin 2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Comparative evaluation of apoptosis induced by Shiga toxin 1 and/or lipopolysaccharides in human monocytic and macrophage-like cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

LC3 conjugation system in mammalian autophagy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxin receptor glycolipid binding. Pathology and utility

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxin-2 triggers endothelial leukocyte adhesion and transmigration via NF-kappaB dependent up-regulation of IL-8 and MCP-1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxin 1-induced activation of c-Jun NH(2)-terminal kinase and p38 in the human monocytic cell line THP-1: possible involvement in the production of TNF-alpha.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Targeting of Shiga toxin B-subunit to retrograde transport route in association with detergent-resistant membranes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Cytoprotective effect of curcumin in human proximal tubule epithelial cells exposed to shiga toxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Binding and transfer of verocytotoxin by polymorphonuclear leukocytes in hemolytic uremic syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Activation of Src family kinase yes induced by Shiga toxin binding to globotriaosyl ceramide (Gb3/CD77) in low density, detergent-insoluble microdomains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxins 1 and 2 translocate differently across polarized intestinal epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Global burden of Shigella infections: implications for vaccine development and implementation of control strategies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

A protein conjugation system essential for autophagy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Shiga toxin type 1 activates tumor necrosis factor-alpha gene transcription and nuclear translocation of the transcriptional activators nuclear factor-kappaB and activator protein-1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Differentiation-associated toxin receptor modulation, cytokine production, and sensitivity to Shiga-like toxins in human monocytes and monocytic cell lines.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Comparison of the relative toxicities of Shiga-like toxins type I and type II for mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

CNS manifestations of the hemolytic-uremic syndrome. Relationship to metabolic alterations and prognosis

28 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Interactions between Shiga toxins and human polymorphonuclear leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Shiga toxin B-subunit binds to the chaperone BiP and the nucleolar protein B23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Structure of shiga toxin type 2 (Stx2) from Escherichia coli O157:H7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Development by self-digestion: molecular mechanisms and biological functions of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Up-regulation of tissue factor activity on human proximal tubular epithelial cells in response to Shiga toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Characterization of non-toxic mutant toxins of Vero toxin 1 that were constructed by replacing amino acids in the A subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Effects of verocytotoxin-1 on nonadherent human monocytes: binding characteristics, protein synthesis, and induction of cytokine release.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173519

Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum

26 September 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01634.X

Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21722286

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impairment by verotoxin of tubular function contributes to the renal damage seen in haemolytic uraemic syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21722286

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1462-5822.2011.01634.X

1 reference

7 August 2017

1 reference

7 August 2017

1 reference