(Q35221034)

7 August 2017

title

An ENU-induced mutation in the Mertk gene (Mertknmf12) leads to a slow form of retinal degeneration (English)

1 reference

7 August 2017

Dennis M Maddox

1

1 reference

7 August 2017

Wanda L Hicks

2

1 reference

7 August 2017

Douglas Vollrath

3

1 reference

7 August 2017

Matthew M LaVail

4

1 reference

7 August 2017

Jürgen K Naggert

5

1 reference

7 August 2017

Patsy M Nishina

6

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 June 2011

1 reference

Investigative Ophthalmology Visual Science

7 August 2017

published in

1 reference

7 August 2017

volume

52

1 reference

7 August 2017

issue

7

1 reference

7 August 2017

page(s)

4703-4709

1 reference

HEREDITARY DEGENERATION OF THE RAT RETINA.

7 August 2017

cites work

1 reference

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Tumor necrosis factor antagonists: preliminary evidence for an emerging approach in the treatment of ocular inflammation

13 July 2018

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Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Clinical characterisation of a family with retinal dystrophy caused by mutation in the Mertk gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Alms1-disrupted mice recapitulate human Alström syndrome

13 July 2018

1 reference

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Both protein S and Gas6 stimulate outer segment phagocytosis by cultured rat retinal pigment epithelial cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

The role of tumour necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

MERTK arginine-844-cysteine in a patient with severe rod-cone dystrophy: loss of mutant protein function in transfected cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Inherited retinal dystrophy in the rat.

13 July 2018

1 reference

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13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Mertk triggers uptake of photoreceptor outer segments during phagocytosis by cultured retinal pigment epithelial cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Retinal dystrophy due to paternal isodisomy for chromosome 1 or chromosome 2, with homoallelism for mutations in RPE65 or MERTK, respectively

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Phagocytosis and clearance of apoptotic cells is mediated by MER.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Retinal dystrophies caused by mutations in RPE65: assessment of visual functions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Evaluation of the Best disease gene in patients with age-related macular degeneration and other maculopathies

13 July 2018

1 reference

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The mutation spectrum of the bestrophin protein--functional implications

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Bestrophin gene mutations in patients with Best vitelliform macular dystrophy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

The gene for the retinal pigment epithelium-specific protein RPE65 is localized to human 1p31 and mouse 3

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Sick photoreceptors attract activated microglia from the ganglion cell layer: a model to study the inflammatory cascades in rats with inherited retinal dystrophy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Interleukin-1 and tumor necrosis factor-alpha: novel targets for immunotherapy in Eales disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Intravitreal administration of the anti-tumor necrosis factor agent infliximab for neovascular age-related macular degeneration.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Novel splice donor site mutation in MERTK gene associated with retinitis pigmentosa

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

An RCS-like retinal dystrophy phenotype in mer knockout mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Successful Treatment With Infliximab in a Patient With Diffuse Subretinal Fibrosis Syndrome

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175976

Optic neuropathy in refractory neurosarcoidosis treated with TNF-alpha antagonist

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21436282

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New ABCR mutations and clinical phenotype in Italian patients with Stargardt disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21436282

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inherited Retinal Dystrophy: Primary Defect in Pigment Epithelium Determined with Experimental Rat Chimeras

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21436282

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1167/IOVS.10-7077

1 reference

7 August 2017

1 reference

7 August 2017

1 reference