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Functions of yeast Hsp40 chaperone Sis1p dispensable for prion propagation but important for prion curing and protection from prion toxicity.
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Europe PubMed Central
PMC publication ID
3176549
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
title
Functions of yeast Hsp40 chaperone Sis1p dispensable for prion propagation but important for prion curing and protection from prion toxicity
(English)
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stated in
Europe PubMed Central
PMC publication ID
3176549
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
main subject
prion protein family
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molecular chaperones
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author
Michael Reidy
series ordinal
2
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Europe PubMed Central
PMC publication ID
3176549
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
author name string
P Aaron Kirkland
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1
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Europe PubMed Central
PMC publication ID
3176549
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
Daniel C Masison
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3
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PMC publication ID
3176549
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
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English
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publication date
9 May 2011
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PMC publication ID
3176549
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31 January 2020
published in
Genetics
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Europe PubMed Central
PMC publication ID
3176549
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
volume
188
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Europe PubMed Central
PMC publication ID
3176549
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
issue
3
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Europe PubMed Central
PMC publication ID
3176549
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31 January 2020
page(s)
565-577
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Europe PubMed Central
PMC publication ID
3176549
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
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ImageJ
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3176549/fullTextXML
based on heuristic
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cites work
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In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104
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Specificity of the J-protein Sis1 in the propagation of 3 yeast prions
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J-protein co-chaperone Sis1 required for generation of [RNQ+] seeds necessary for prion propagation
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N-terminal domain of yeast Hsp104 chaperone is dispensable for thermotolerance and prion propagation but necessary for curing prions by Hsp104 overexpression
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Saccharomyces cerevisiae Hsp70 mutations affect [PSI+] prion propagation and cell growth differently and implicate Hsp40 and tetratricopeptide repeat cochaperones in impairment of [PSI+]
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Getting started with yeast
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Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor
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A conserved HPD sequence of the J-domain is necessary for YDJ1 stimulation of Hsp70 ATPase activity at a site distinct from substrate binding
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The ATP hydrolysis-dependent reaction cycle of the Escherichia coli Hsp70 system DnaK, DnaJ, and GrpE
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The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae
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Non-Mendelian Mutation Allowing Ureidosuccinic Acid Uptake in Yeast
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27 July 2018
5-Fluoroorotic acid as a selective agent in yeast molecular genetics
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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
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27 July 2018
Interaction of the yeast omnipotent suppressors SUP1(SUP45) and SUP2(SUP35) with non-mendelian factors
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27 July 2018
Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein
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27 July 2018
Characterization of SIS1, a Saccharomyces cerevisiae homologue of bacterial dnaJ proteins
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27 July 2018
Multifunctional yeast high-copy-number shuttle vectors
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27 July 2018
Regulation of Hsp70 function by a eukaryotic DnaJ homolog
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27 July 2018
Destabilization and recovery of a yeast prion after mild heat shock.
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26 September 2018
Sti1 regulation of Hsp70 and Hsp90 is critical for curing of Saccharomyces cerevisiae [PSI+] prions by Hsp104.
1 reference
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26 September 2018
Hsp70/Hsp90 co-chaperones are required for efficient Hsp104-mediated elimination of the yeast [PSI(+)] prion but not for prion propagation
1 reference
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26 September 2018
Prion-impairing mutations in Hsp70 chaperone Ssa1: effects on ATPase and chaperone activities
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26 September 2018
Modulation of prion-dependent polyglutamine aggregation and toxicity by chaperone proteins in the yeast model.
1 reference
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26 September 2018
The prion curing agent guanidinium chloride specifically inhibits ATP hydrolysis by Hsp104.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3176549
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26 September 2018
Identification of essential residues in the type II Hsp40 Sis1 that function in polypeptide binding
1 reference
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PubMed Central
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26 September 2018
The elimination of the yeast [PSI+] prion by guanidine hydrochloride is the result of Hsp104 inactivation
1 reference
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PubMed Central
reference URL
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26 September 2018
The NH2-terminal 108 amino acids of the Escherichia coli DnaJ protein stimulate the ATPase activity of DnaK and are sufficient for lambda replication.
1 reference
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26 September 2018
[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae
1 reference
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26 September 2018
Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3176549
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26 September 2018
Rnq1: an epigenetic modifier of protein function in yeast
1 reference
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PubMed
reference URL
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retrieved
12 December 2020
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inferred from PubMed ID database lookup
Identifiers
DOI
10.1534/GENETICS.111.129460
1 reference
stated in
Europe PubMed Central
PMC publication ID
3176549
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
PMC publication ID
3176549
1 reference
stated in
Europe PubMed Central
PMC publication ID
3176549
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
PubMed publication ID
21555396
1 reference
stated in
Europe PubMed Central
PMC publication ID
3176549
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
ResearchGate publication ID
51110600
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