(Q35224290)

English

Metabotropic glutamate receptor 5 upregulation in children with autism is associated with underexpression of both Fragile X mental retardation protein and GABAA receptor beta 3 in adults with autism

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1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Metabotropic glutamate receptor 5 upregulation in children with autism is associated with underexpression of both Fragile X mental retardation protein and GABAA receptor beta 3 in adults with autism (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

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1 reference

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author name string

S Hossein Fatemi

1

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Timothy D Folsom

2

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Rachel E Kneeland

3

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Stephanie B Liesch

4

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

publication date

8 September 2011

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Europe PubMed Central

PubMed publication ID

7 August 2017

number of pages

11

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The Anatomical Record

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Europe PubMed Central

PubMed publication ID

7 August 2017

294

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

1635-1645

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

mRNA and protein levels for GABAAalpha4, alpha5, beta1 and GABABR1 receptors are altered in brains from subjects with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

A comprehensive volumetric analysis of the cerebellum in children and adolescents with autism spectrum disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Fragile X mental retardation protein control of neuronal mRNA metabolism: Insights into mRNA stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Decreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Cerebellar vermal volumes and behavioral correlates in children with autism spectrum disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

FMR1: a gene with three faces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

A pilot open label, single dose trial of fenobam in adults with fragile X syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Cerebellar disorders in childhood: cognitive problems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Expression of GABA(B) receptors is altered in brains of subjects with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

GABA(A) receptor downregulation in brains of subjects with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Immune transcriptome alterations in the temporal cortex of subjects with autism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Correction of fragile X syndrome in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Group I metabotropic glutamate receptors: a role in neurodevelopmental disorders?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

RNA regulons: coordination of post-transcriptional events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Local protein synthesis and spine morphogenesis: Fragile X syndrome and beyond.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

GABAergic cerebellar system in autism: a neuropathological and developmental perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Reelin signaling is impaired in autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Neuroglial activation and neuroinflammation in the brain of patients with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Neuropathological findings in autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

The mGluR theory of fragile X mental retardation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Metabotropic glutamate receptors in the cerebellum with a focus on their function in Purkinje cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Homologous sites of GABA(A) receptor alpha(1), beta(3) and gamma(2) subunits are important for assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Role of excitatory amino acids in developmental epilepsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Postmortem brain abnormalities of the glutamate neurotransmitter system in autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Cajal-Retzius cell physiology: just in time to bridge the 20th century

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Prevalence and phenotype consequence of FRAXA and FRAXE alleles in a large, ethnically diverse, special education-needs population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

The metabotropic glutamate receptor mGlu5 controls the onset of developmental apoptosis in cultured cerebellar neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Light and electron microscopic demonstration of mGluR5 metabotropic glutamate receptor immunoreactive neuronal elements in the rat cerebellar cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Metabotropic glutamate receptors mGluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Multiple distinct subunits of the gamma-aminobutyric acid-A receptor protein show different ligand-binding affinities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

13 July 2018

Levels of Bcl-2 and P53 are altered in superior frontal and cerebellar cortices of autistic subjects

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Early development, temperament, and functional impairment in autism and fragile X syndrome.

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https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Density and distribution of hippocampal neurotransmitter receptors in autism: an autoradiographic study

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Decreased expression of the GABAA receptor in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Altered levels of Bcl2 and p53 proteins in parietal cortex reflect deranged apoptotic regulation in autism.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Reduced blood levels of reelin as a vulnerability factor in pathophysiology of autistic disorder

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Expression profiling suggests underexpression of the GABA(A) receptor subunit delta in the fragile X knockout mouse model

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Autistic behavior in children with fragile X syndrome: prevalence, stability, and the impact of FMRP.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Fragile X mental retardation protein levels increase following complex environment exposure in rat brain regions undergoing active synaptogenesis

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Autism spectrum disorder in fragile X syndrome: communication, social interaction, and specific behaviors.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Glial fibrillary acidic protein is elevated in superior frontal, parietal and cerebellar cortices of autistic subjects

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Differential distribution of group I metabotropic glutamate receptors during rat cortical development

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Epilepsy and EEG findings in males with fragile X syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Up-regulation of hippocampal metabotropic glutamate receptor 5 in temporal lobe epilepsy patients

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Cholinergic activity in autism: abnormalities in the cerebral cortex and basal forebrain

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Enhanced early developmental expression of the metabotropic glutamate receptor mGluR5 in rat brain: protein, mRNA splice variants, and regional distribution.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Induction of astrogliosis by activated microglia is associated with a down-regulation of metabotropic glutamate receptor 5.

1 reference

https://api.crossref.org/works/10.1002%2FAR.21299

21 January 2018

Abnormal striatal GABA transmission in the mouse model for the fragile X syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177171

26 September 2018

Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21901840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological characteristics of Lugaro cells in the cerebellar cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/21901840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21901840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulator of G-protein signaling 4 interacts with metabotropic glutamate receptor subtype 5 in rat striatum: relevance to amphetamine behavioral sensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/21901840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/AR.21299

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Europe PubMed Central

PubMed publication ID

7 August 2017

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https://api.fatcat.wiki/v0/release/prxadv7jljfjte56juxssjjn2y

24 November 2022

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PMC publication ID

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Europe PubMed Central

PubMed publication ID

7 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

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