(Q35227161)

7 August 2017

title

Inhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance (English)

1 reference

7 August 2017

Mia C Akerfeldt

1

1 reference

7 August 2017

D Ross Laybutt

series ordinal

2

1 reference

7 August 2017

language of work or name

English

0 references

publication date

22 September 2011

1 reference

7 August 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Diabetes

1 reference

7 August 2017

volume

60

1 reference

7 August 2017

issue

10

1 reference

7 August 2017

page(s)

2506-2514

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

7 August 2017

copyright license

start time

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Towards better understanding of the contributions of overwork and glucotoxicity to the beta-cell inadequacy of type 2 diabetes

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The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.

13 July 2018

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ID2 promotes the expansion and survival of growth-arrested pancreatic beta cells

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Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes

13 July 2018

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Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function

13 July 2018

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13 July 2018

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Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation

13 July 2018

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Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells

13 July 2018

1 reference

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13 July 2018

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13 July 2018

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13 July 2018

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Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

13 July 2018

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13 July 2018

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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

13 July 2018

1 reference

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High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

13 July 2018

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Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

13 July 2018

1 reference

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Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Pancreatic beta-cell mass in European subjects with type 2 diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Inhibition of PKCepsilon improves glucose-stimulated insulin secretion and reduces insulin clearance.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

BMP4 regulates pancreatic progenitor cell expansion through Id2.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Constitutive differences in antioxidant defense status distinguish alloxan-resistant and alloxan-susceptible mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Expression of Id1 results in apoptosis of cardiac myocytes through a redox-dependent mechanism.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178288

Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21940780

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21940780

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB11-0083

1 reference

7 August 2017

1 reference

7 August 2017

1 reference