(Q35229446)

7 August 2017

title

ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading-induced autophagy (English)

1 reference

7 August 2017

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Shuhui Wang

1

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7 August 2017

Peggy Robinet

series ordinal

2

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7 August 2017

Jonathan D Smith

series ordinal

3

1 reference

7 August 2017

Kailash Gulshan

series ordinal

4

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7 August 2017

language of work or name

English

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publication date

9 March 2015

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Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

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7 August 2017

volume

112

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7 August 2017

issue

12

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7 August 2017

page(s)

3728-3733

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Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis

7 August 2017

cites work

1 reference

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Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis

13 July 2018

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Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux

13 July 2018

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ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48.

13 July 2018

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2H2O-based high-density lipoprotein turnover method for the assessment of dynamic high-density lipoprotein function in mice

13 July 2018

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Physiological difference in autophagic flux in macrophages from 2 mouse strains regulates cholesterol ester metabolism

13 July 2018

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Sphingolipids and atherosclerosis

13 July 2018

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Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis

13 July 2018

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Macrophage autophagy plays a protective role in advanced atherosclerosis

13 July 2018

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Autophagy links inflammasomes to atherosclerotic progression.

13 July 2018

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Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae

13 July 2018

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Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase

13 July 2018

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Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes.

13 July 2018

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Macrophages in the pathogenesis of atherosclerosis

13 July 2018

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A simple and sensitive enzymatic method for cholesterol quantification in macrophages and foam cells

13 July 2018

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Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control

13 July 2018

1 reference

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Orm family proteins mediate sphingolipid homeostasis

13 July 2018

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Myriocin-mediated up-regulation of hepatocyte apoA-I synthesis is associated with ERK inhibition

13 July 2018

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Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver

13 July 2018

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Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol

13 July 2018

1 reference

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An improved method to determine serine palmitoyltransferase activity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

13 July 2018

1 reference

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Cloning and initial characterization of a new subunit for mammalian serine-palmitoyltransferase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

The rate of sphingomyelin synthesis de novo is influenced by the level of cholesterol in cultured human skin fibroblasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Parallel regulation of sterol regulatory element binding protein-2 and the enzymes of cholesterol and fatty acid synthesis but not ceramide synthesis in cultured human keratinocytes and murine epidermis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Cholesterol and sphingomyelin syntheses are regulated independently in cultured human intestinal cells, CaCo-2: role of membrane cholesterol and sphingomyelin content

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Free cholesterol loading of macrophages stimulates phosphatidylcholine biosynthesis and up-regulation of CTP: phosphocholine cytidylyltransferase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Localization of cholesterol in sphingomyelinase-treated fibroblasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Metabolism of sphingolipids by normal and atherosclerotic aorta of squirrel monkeys

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Myriocin slows the progression of established atherosclerotic lesions in apolipoprotein E gene knockout mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Rapid, specific, and sensitive measurements of plasma sphingomyelin and phosphatidylcholine

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Plasma sphingomyelin level as a risk factor for coronary artery disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378419

Effects of sphingomyelin degradation on cholesterol mobilization and efflux to high-density lipoproteins in cultured fibroblasts

26 September 2018

1 reference

12 December 2020

Sphingomyelinase enhances low density lipoprotein uptake and ability to induce cholesteryl ester accumulation in macrophages

1 reference

12 December 2020

25-Hydroxycholesterol stimulates sphingomyelin synthesis in Chinese hamster ovary cells

1 reference

12 December 2020

Evidence that the initial up-regulation of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response that prevents cholesterol-induced cellular necrosis. Proposed role of an eventual failure of this response in

1 reference

12 December 2020

Effects of sphingomyelin and phosphatidylcholine degradation on cyclodextrin-mediated cholesterol efflux in cultured fibroblasts

1 reference

12 December 2020

Intimal and medial lipids in human aortas

1 reference

12 December 2020

Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1422455112

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7 August 2017

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7 August 2017

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