(Q35230894)

English

17beta-Estradiol attenuates diabetic kidney disease by regulating extracellular matrix and transforming growth factor-beta protein expression and signaling

scientific article

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

17beta-Estradiol attenuates diabetic kidney disease by regulating extracellular matrix and transforming growth factor-beta protein expression and signaling (English)

1 reference

Europe PubMed Central

7 August 2017

extracellular matrix

0 references

1 reference

based on heuristic

inferred from title

author name string

Alexis Dixon

1

1 reference

Europe PubMed Central

7 August 2017

Christine Maric

2

1 reference

Europe PubMed Central

7 August 2017

publication date

8 August 2007

1 reference

Europe PubMed Central

7 August 2017

American Journal of Physiology - Renal Physiology

1 reference

Europe PubMed Central

7 August 2017

293

1 reference

Europe PubMed Central

7 August 2017

5

1 reference

Europe PubMed Central

7 August 2017

F1678-90

1 reference

Europe PubMed Central

7 August 2017

Differential effects of continuous and intermittent 17beta-estradiol replacement and tamoxifen therapy on the prevention of glomerulosclerosis: modulation of the mesangial cell phenotype in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Sex differences and the role of sex steroids in renal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Enhancing the predictive value of urinary albumin for diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Plasminogen activator inhibitor-1 and diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Estrogen and raloxifene, a selective estrogen receptor modulator, ameliorate renal damage in db/db mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Transforming growth factor-beta and Smad signalling in kidney diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Mechanisms of tubulointerstitial injury in the kidney: final common pathways to end-stage renal failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

The impact of gender on progression of renal disease: potential role of estrogen-mediated vascular endothelial growth factor regulation and vascular protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

The role of renal proximal tubular cells in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Growth factors and the development of diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Ubiquitin-Dependent Degradation of Smad2 Is Increased in the Glomeruli of Rats with Anti-Thymocyte Serum Nephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Extracellular matrix metabolism in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Estrogen deficiency accelerates progression of glomerulosclerosis in susceptible mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

The role of gender in the progression of renal disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Renal damage associated with proteinuria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Inhibitory smads and tgf-Beta signaling in glomerular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Transformation of interstitial fibroblasts and tubulointerstitial fibrosis in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Angiotensin II induces human TGF-beta 1 promoter activation: similarity to hyperglycaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Estrogen-related abnormalities in glomerulosclerosis-prone mice: reduced mesangial cell estrogen receptor expression and prosclerotic response to estrogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Diabetic nephropathy: the central role of renal proximal tubular cells in tubulointerstitial injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Estradiol upregulates mesangial cell MMP-2 activity via the transcription factor AP-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Increased glomerular and tubular expression of transforming growth factor-beta1, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Effects of estradiol and its metabolites on glomerular endothelial nitric oxide synthesis and mesangial cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Expression and regulation of estrogen receptors in mesangial cells: influence on matrix metalloproteinase-9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Selective estrogen receptor modulators suppress mesangial cell collagen synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Regulation of Smad activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

TGF-beta and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Estradiol suppresses type I collagen synthesis in mesangial cells via activation of activator protein-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Estradiol reverses TGF-beta1-stimulated type IV collagen gene transcription in murine mesangial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Transforming growth factor beta in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

The extracellular matrix in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

The enhancement of aminonucleoside nephrosis by the co-administration of protamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

13 July 2018

17beta-Estradiol supplementation reduces tubulointerstitial fibrosis by increasing MMP activity in the diabetic kidney.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Diabetic nephropathy is associated with decreased circulating estradiol levels and imbalance in the expression of renal estrogen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Gender differences in renal responses to hyperglycemia and angiotensin-converting enzyme inhibition in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Estradiol reverses renal injury in Alb/TGF-beta1 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

AGEs activate mesangial TGF-beta-Smad signaling via an angiotensin II type I receptor interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Heterozygous mice for TGF-betaIIR gene are resistant to the progression of streptozotocin-induced diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

17beta-Estradiol replacement improves renal function and pathology associated with diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Calcium channel blockers, either amlodipine or mibefradil, ameliorate renal injury in experimental diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Effects of pioglitazone on expressions of matrix metalloproteinases 2 and 9 in kidneys of diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Glomerulosclerosis and tubulointerstitial fibrosis are attenuated with 17beta-estradiol in the aging Dahl salt sensitive rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Transforming growth factor beta1-induced glomerulopathy is prevented by 17beta-estradiol supplementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Urinary connective tissue growth factor excretion in patients with type 1 diabetes and nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Catecholamines block the antimitogenic effect of estradiol on human glomerular mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Estradiol is nephroprotective in the rat remnant kidney.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Estradiol reverses TGF-beta1-induced mesangial cell apoptosis by a casein kinase 2-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Decreased matrix degradation in diabetic nephropathy: effects of ACE inhibition on the expression and activities of matrix metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Cross-talk between transforming growth factor-beta and estrogen receptor signaling through Smad3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Postmenopausal hormone replacement improves proteinuria and impaired creatinine clearance in type 2 diabetes mellitus and hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

26 September 2018

Beneficial effect of TGFbeta antagonism in treating diabetic nephropathy depends on when treatment is started

2 references

https://api.crossref.org/works/10.1152%2FAJPRENAL.00079.2007

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179625

24 October 2018

Extracellular matrix proteins as early markers in diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictors of the progression of renal insufficiency in patients with insulin-dependent diabetes and overt diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased renal production of transforming growth factor-beta1 in patients with type II diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pioglitazone mitigates renal glomerular vascular changes in high-fat, high-calorie-induced type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different effects of castration and estrogen administration on glomerular injury in spontaneously hyperglycemic Otsuka Long-Evans Tokushima Fatty (OLETF) rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the Smad pathway in glomeruli from a spontaneously diabetic rat model, OLETF rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of gender on the progression of nondiabetic renal disease: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The renal expression of transforming growth factor-beta isoforms and their receptors in acute and chronic experimental diabetes in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical stretch-induced fibronectin and transforming growth factor-beta1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G1 kinases and transforming growth factor-beta signaling are associated with a growth pattern switch in diabetes-induced renal growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of hormonal replacement therapy on lipid and haemostatic factors in post-menopausal ESRD patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17686959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPRENAL.00079.2007

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

ResearchGate publication ID

0 references

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