(Q35235683)

7 August 2017

title

Epac1-mediated, high glucose-induced renal proximal tubular cells hypertrophy via the Akt/p21 pathway (English)

1 reference

7 August 2017

Lin Sun

1

1 reference

7 August 2017

Vinay K Kondeti

2

1 reference

7 August 2017

Ping Xie

3

1 reference

7 August 2017

Kirtee Raparia

4

1 reference

7 August 2017

Yashpal S Kanwar

5

1 reference

7 August 2017

language of work or name

English

0 references

publication date

18 August 2011

1 reference

The American Journal of Pathology

7 August 2017

published in

1 reference

7 August 2017

volume

179

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7 August 2017

issue

4

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7 August 2017

page(s)

1706-1718

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describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3181352/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells.

13 July 2018

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13 July 2018

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13 July 2018

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High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway

13 July 2018

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Isolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy

13 July 2018

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3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Biochemistry and molecular cell biology of diabetic complications

13 July 2018

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13 July 2018

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High glucose-induced hypertrophy of mesangial cells requires p27(Kip1), an inhibitor of cyclin-dependent kinases

13 July 2018

1 reference

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

13 July 2018

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Small GTP-binding proteins

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Effect of lovastatin on small GTP binding proteins and on TGF-beta1 and fibronectin expression.

13 July 2018

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Cell cycle regulation in diabetic nephropathy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

TGF-beta1-mediated hypertrophy involves inhibiting pRB phosphorylation by blocking activation of cyclin E kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Molecular mechanisms of diabetic renal hypertrophy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

A novel factor binding to the glucose response elements of liver pyruvate kinase and fatty acid synthase genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Transcriptional activation of transforming growth factor-beta1 in mesangial cell culture by high glucose concentration

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Characterization of mammalian translocase of inner mitochondrial membrane (Tim44) isolated from diabetic newborn mouse kidney

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

The Ras superfamilies: regulatory proteins and post-translational modifications

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Tubulointerstitial changes as a major determinant in the progression of renal damage

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

A model for diabetic nephropathy: advantages of the inducible cAMP early repressor transgenic mouse over the streptozotocin-induced diabetic mouse.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Cellular and molecular mechanisms of proteinuria in diabetic nephropathy.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Sp1 and Smad3 are required for high glucose-induced p21(WAF1) gene transcription in LLC-PK1 cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

cAMP-binding protein Epac induces cardiomyocyte hypertrophy.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

RAGE- and TGF-beta receptor-mediated signals converge on STAT5 and p21waf to control cell-cycle progression of mesangial cells: a possible role in the development and progression of diabetic nephropathy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Relevance of renal-specific oxidoreductase in tubulogenesis during mammalian nephron development.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

cAMP-dependent protein kinase and proliferation differ in normal and polycystic kidney epithelia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Involvement of Cdc25A phosphatase in Hep3B hepatoma cell growth inhibition induced by novel K vitamin analogs.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Renal tubular hypertrophy induced by angiotensin II.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3181352

Epac-mediated Ca(2+) mobilization and exocytosis in inner medullary collecting duct

26 September 2018

1 reference

12 December 2020

Cellular distribution of calcium current is unaltered during compensated hypertrophy in the spontaneously hypertensive rat

1 reference

12 December 2020

Glucose regulation of mouse S(14) gene expression in hepatocytes. Involvement of a novel transcription factor complex

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12 December 2020

Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice

1 reference

12 December 2020

The tubulointerstitium in progressive renal disease

1 reference

12 December 2020

10.1016/J.AJPATH.2011.06.035

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

1 reference