(Q35273555)

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Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma.

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26 February 2020

Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma (English)

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26 February 2020

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26 February 2020

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Tiansuo Zhao

1

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26 February 2020

He Ren

2

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26 February 2020

Jing Chen

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26 February 2020

Wen Xin

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26 February 2020

Fan Yan

6

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26 February 2020

Jing Li

7

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26 February 2020

Xiuchao Wang

8

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26 February 2020

Song Gao

9

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26 February 2020

Dong Qian

10

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26 February 2020

Chongbiao Huang

11

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26 February 2020

Jihui Hao

12

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26 February 2020

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1 February 2015

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26 February 2020

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26 February 2020

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26 February 2020

4

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26 February 2020

2250-2262

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26 February 2020

FOLFIRINOX - a new paradigm in the treatment of pancreatic cancer

1 reference

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27 July 2018

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1 reference

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1 reference

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27 July 2018

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1 reference

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27 July 2018

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

1 reference

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27 July 2018

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385849

27 July 2018

HIF-1 signaling in drug resistance to chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385849

27 July 2018

Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.

1 reference

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27 July 2018

An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385849

27 July 2018

Hypoxia-inducible factor-1 promotes pancreatic ductal adenocarcinoma invasion and metastasis by activating transcription of the actin-bundling protein fascin

1 reference

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27 July 2018

Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer

1 reference

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27 July 2018

High hydrostatic pressure induces immunogenic cell death in human tumor cells

1 reference

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Extracellular HMGB1 promotes differentiation of nurse-like cells in chronic lymphocytic leukemia.

1 reference

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27 July 2018

Cancer statistics, 2014

1 reference

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27 July 2018

Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments

1 reference

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27 July 2018

Immunogenic tumor cell death induced by chemoradiotherapy: molecular mechanisms and a clinical translation

1 reference

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27 July 2018

An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.

1 reference

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27 July 2018

Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer

1 reference

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27 July 2018

Immunogenic cell death in cancer therapy

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27 July 2018

Current concepts and novel targets in advanced pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385849

27 July 2018

Hypoxia-inducible factor-1α regulates chemotactic migration of pancreatic ductal adenocarcinoma cells through directly transactivating the CX3CR1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385849

27 July 2018

Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function

1 reference

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27 July 2018

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

1 reference

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27 July 2018

Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia

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27 July 2018

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1 reference

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27 July 2018

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1 reference

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27 July 2018

The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects

1 reference

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27 July 2018

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385849

27 July 2018

High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385849

27 July 2018

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1 reference

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27 July 2018

Immunological aspects of cancer chemotherapy

1 reference

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27 July 2018

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385849

27 July 2018

Calreticulin exposure dictates the immunogenicity of cancer cell death

1 reference

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27 July 2018

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1 reference

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27 July 2018

Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha.

1 reference

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1 reference

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27 July 2018

Gemcitabine resistance is associated with epithelial-mesenchymal transition and induction of HIF-1α in pancreatic cancer cells

1 reference

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26 September 2018

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1 reference

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26 September 2018

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1 reference

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26 September 2018

The CX3CL1/CX3CR1 reprograms glucose metabolism through HIF-1 pathway in pancreatic adenocarcinoma

1 reference

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26 September 2018

IgG4 subclass antibodies impair antitumor immunity in melanoma.

1 reference

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26 September 2018

Low-dose gemcitabine depletes regulatory T cells and improves survival in the orthotopic Panc02 model of pancreatic cancer.

1 reference

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1 reference

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1 reference

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Hypoxia-inducible factors in physiology and medicine

1 reference

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26 September 2018

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1 reference

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1 reference

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1 reference

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12 December 2020

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26 February 2020

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24 November 2022

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26 February 2020

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26 February 2020

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