(Q35288031)

English

Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration

scientific article

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration (English)

1 reference

Europe PubMed Central

7 August 2017

arterial hypertension

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pulmonary hypertension

1 reference

based on heuristic

inferred from title

author name string

David C Irwin

1

1 reference

Europe PubMed Central

7 August 2017

Jin Hyen Baek

2

1 reference

Europe PubMed Central

7 August 2017

Kathryn Hassell

3

1 reference

Europe PubMed Central

7 August 2017

Rachelle Nuss

4

1 reference

Europe PubMed Central

7 August 2017

Paul Eigenberger

5

1 reference

Europe PubMed Central

7 August 2017

Christina Lisk

6

1 reference

Europe PubMed Central

7 August 2017

Zoe Loomis

7

1 reference

Europe PubMed Central

7 August 2017

Joanne Maltzahn

8

1 reference

Europe PubMed Central

7 August 2017

Kurt R Stenmark

9

1 reference

Europe PubMed Central

7 August 2017

Eva Nozik-Grayck

10

1 reference

Europe PubMed Central

7 August 2017

Paul W Buehler

11

1 reference

Europe PubMed Central

7 August 2017

publication date

2 February 2015

1 reference

Europe PubMed Central

7 August 2017

Free Radical Biology and Medicine

1 reference

Europe PubMed Central

7 August 2017

82

1 reference

Europe PubMed Central

7 August 2017

50-62

1 reference

Europe PubMed Central

7 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4387123/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapies

1 reference

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12 July 2018

The role of disturbed blood flow in the development of pulmonary arterial hypertension: lessons from preclinical animal models

1 reference

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12 July 2018

The adventitia: essential regulator of vascular wall structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Structure of the haptoglobin-haemoglobin complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

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Hemoglobin directs macrophage differentiation and prevents foam cell formation in human atherosclerotic plaques

1 reference

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12 July 2018

The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension

1 reference

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12 July 2018

Blood-brain barrier disruption and oxidative stress in guinea pig after systemic exposure to modified cell-free hemoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine

1 reference

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Beta-thalassemia cardiomyopathy: history, present considerations, and future perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Hemin and a metabolic derivative coprohemin modulate the TLR4 pathway differently through different molecular targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Pulmonary hypertension and nitric oxide depletion in sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Pleiotropic effects of intravascular haemolysis on vascular homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Toxicological consequences of extracellular hemoglobin: biochemical and physiological perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Inheritance of haptoglobin subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Catalase in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Non-specific serum iron in thalassaemia: an abnormal serum iron fraction of potential toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Acceleration of tetramer formation by the binding of inositol hexaphosphate to hemoglobin dimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 July 2018

Toll-like receptor 4-deficient mice are resistant to chronic hypoxia-induced pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 August 2018

Clearance and control mechanisms of hemoglobin from cradle to grave.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 August 2018

Deferoxamine lowers tissue damage after 80% exchange transfusion with polymerized hemoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

12 August 2018

Updated Clinical Classification of Pulmonary Hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387123

26 September 2018

Pulmonary complications of sickle cell disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25656991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide synthase in pulmonary hypertension: lessons from knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25656991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological intervention for renal protection during cardiopulmonary bypass

1 reference

https://pubmed.ncbi.nlm.nih.gov/25656991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haptoglobin determination in diagnosis of haemolytic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/25656991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subdivision of the Three Common Haptoglobin Types based on ‘Hidden’ Differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/25656991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathology of pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/25656991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.FREERADBIOMED.2015.01.012

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

ResearchGate publication ID

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