(Q35299829)

7 August 2017

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title

Clusters of genes for the biosynthesis of antibiotics: regulatory genes and overproduction of pharmaceuticals (English)

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Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase precursor

7 August 2017

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Isopenicillin-N synthase

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Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, putative

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author name string

Martin JF

series ordinal

1

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7 August 2017

1 February 1992

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Journal of Industrial Microbiology & Biotechnology

7 August 2017

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7 August 2017

9

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7 August 2017

73-90

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7 August 2017

2

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Cloning and characterization of the isopenicillin N synthase gene of Streptomyces griseus NRRL 3851 and studies of expression and complementation of the cephamycin pathway in Streptomyces clavuligerus

7 August 2017

1 reference

https://api.crossref.org/works/10.1007%2FBF01569737

Isolation and nature of intracellular peptides from a cephalosporin C-producing Cephalosporium sp

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01569737

Purification of an inducible L-valine dehydrogenase of Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01569737

Isopenicillin N synthetase of Penicillium chrysogenum, an enzyme that converts delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01569737

Streptomyces cloning: possible construction of novel compounds and regulation of antibiotic biosynthetic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01569737

Purification and characterization of the isopenicillin N epimerase from Nocardia lactamdurans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01569737

Cloning and characterization of a gene ofStreptomyces griseus that increases production of extracellular enzymes in several species ofStreptomyces

21 January 2018

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12 December 2020

Purification and characterization of the isopenicillin N synthase of Streptomyces lactamdurans

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12 December 2020

Analysis of the role of cysteine residues in isopenicillin N synthetase activity by site-directed mutagenesis

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12 December 2020

Control of antibiotic biosynthesis

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12 December 2020

Expression of the penDE gene of Penicillium chrysogenum encoding isopenicillin N acyltransferase in Cephalosporium acremonium: production of benzylpenicillin by the transformants

1 reference

12 December 2020

Transformation of Aspergillus nidulans by using a trpC plasmid

1 reference

12 December 2020

Genetic analysis of erythromycin production in Streptomyces erythreus

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12 December 2020

Cloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp.

1 reference

12 December 2020

The cluster of penicillin biosynthetic genes. Identification and characterization of the pcbAB gene encoding the alpha-aminoadipyl-cysteinyl-valine synthetase and linkage to the pcbC and penDE genes

1 reference

12 December 2020

Glucose represses formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine and isopenicillin N synthase but not penicillin acyltransferase in Penicillium chrysogenum

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12 December 2020

Sequences important for gene expression in filamentous fungi.

1 reference

12 December 2020

Acyl coenzyme A: 6-aminopenicillanic acid acyltransferase from Penicillium chrysogenum and Aspergillus nidulans

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12 December 2020

Enzymes involved in penicillin, cephalosporin and cephamycin biosynthesis.

1 reference

12 December 2020

Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum

1 reference

12 December 2020

A Pigmented Mycelial Antibiotic in Streptomyces coelicolor: Control by a Chromosomal Gene Cluster

1 reference

12 December 2020

The glucose kinase gene of Streptomyces coelicolor and its use in selecting spontaneous deletions for desired regions of the genome

1 reference

12 December 2020

Genetic analysis of A-factor synthesis in Streptomyces coelicolor A3(2) and Streptomyces griseus

1 reference

12 December 2020

The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum

1 reference

12 December 2020

Phosphate regulation of ACV synthetase and cephalosporin biosynthesis in Streptomyces clavuligerus

1 reference

12 December 2020

Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate

1 reference

12 December 2020

The biosynthesis of sulfur-containing beta-lactam antibiotics

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12 December 2020

afsB stimulates transcription of the actinorhodin biosynthetic pathway in Streptomyces coelicolor A3(2) and Streptomyces lividans

1 reference

12 December 2020

Cloning, characterization of the acyl-CoA:6-amino penicillanic acid acyltransferase gene of Aspergillus nidulans and linkage to the isopenicillin N synthase gene

1 reference

12 December 2020

A cloned regulatory gene of Streptomyces lividans can suppress the pigment deficiency phenotype of different developmental mutants

1 reference

12 December 2020

A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans

1 reference

12 December 2020

Cloning, sequence analysis and transcriptional study of the isopenicillin N synthase of Penicillium chrysogenum AS-P-78.

1 reference

12 December 2020

Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans

1 reference

12 December 2020

Cell-free synthesis of delta-(L-alpha-aminoadipyl)-L-cysteine, the first intermediate of penicillin and cephalosporin biosynthesis

1 reference

12 December 2020

Effect of primary metabolites on secondary metabolism

1 reference

12 December 2020

Cloning and heterologous expression in Streptomyces lividans of Streptomyces rimosus genes involved in oxytetracycline biosynthesis

1 reference

12 December 2020

Gene cluster containing the genes for tyrocidine synthetases 1 and 2 from Bacillus brevis: evidence for an operon

1 reference

12 December 2020

Purification and partial characterization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Streptomyces clavuligerus

1 reference

12 December 2020

Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2).

1 reference

12 December 2020

Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity

1 reference

12 December 2020

Characterization and regulation of p-aminobenzoic acid synthase from Streptomyces griseus

1 reference

12 December 2020

L-lysine epsilon-aminotransferase involved in cephamycin C synthesis in Streptomyces lactamdurans

1 reference

12 December 2020

Molecular cloning of resistance genes and architecture of a linked gene cluster involved in biosynthesis of oxytetracycline by Streptomyces rimosus.

1 reference

12 December 2020

An electrophoretic molecular karyotype for an industrial strain of Cephalosporium acremonium

1 reference

12 December 2020

1 reference

12 December 2020

Phosphorylation of the AfsR product, a global regulatory protein for secondary-metabolite formation in Streptomyces coelicolor A3(2).

1 reference

12 December 2020

Microbial isopenicillin N synthase genes: structure, function, diversity and evolution

1 reference

12 December 2020

Genetics of antibiotic production

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12 December 2020

Characterization of a loss-of-function mutation in the isopenicillin N synthetase gene of Acremonium chrysogenum

1 reference

12 December 2020

The improving prospects for yield increase by genetic engineering in antibiotic-producing Streptomycetes

1 reference

12 December 2020

Cloning and characterization of the acyl-coenzyme A: 6-aminopenicillanic-acid-acyltransferase gene of Penicillium chrysogenum

1 reference

12 December 2020

Organization and expression of genes involved in the biosynthesis of antibiotics and other secondary metabolites

1 reference

12 December 2020

Gramicidin S biosynthesis operon containing the structural genes grsA and grsB has an open reading frame encoding a protein homologous to fatty acid thioesterases

1 reference

12 December 2020

Cloning of a Streptomyces gene for an O-methyltransferase involved in antibiotic biosynthesis

1 reference

12 December 2020

Glucose regulation of cephamycin biosynthesis in Streptomyces lactamdurans is exerted on the formation of alpha-aminoadipyl-cysteinyl-valine and deacetoxycephalosporin C synthase

1 reference

12 December 2020

delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. The first enzyme in penicillin biosynthesis is a multifunctional peptide synthetase.

1 reference

12 December 2020

Self-cloning in Streptomyces griseus of an str gene cluster for streptomycin biosynthesis and streptomycin resistance

1 reference

12 December 2020

Gene cluster for streptomycin biosynthesis in Streptomyces griseus: analysis of a central region including the major resistance gene.

1 reference

12 December 2020

Purification and properties of isopenicillin N epimerase from Streptomyces clavuligerus

1 reference

12 December 2020

Transcriptional regulation of bialaphos biosynthesis in Streptomyces hygroscopicus

1 reference

12 December 2020

Cloning and characterization of the isopenicillin N synthetase gene mediating the formation of the beta-lactam ring in Aspergillus nidulans.

1 reference

12 December 2020

Genetic studies of avermectin biosynthesis in Streptomyces avermitilis

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12 December 2020

Purification to homogeneity and characterization of acyl coenzyme A:6-aminopenicillanic acid acyltransferase of Penicillium chrysogenum

1 reference

12 December 2020

Cloning of a pleiotropic gene that positively controls biosynthesis of A-factor, actinorhodin, and prodigiosin in Streptomyces coelicolor A3(2) and Streptomyces lividans

1 reference

12 December 2020

Genetic determination of methylenomycin synthesis by the SCP1 plasmid of Streptomyces coelicolor A3(2)

1 reference

12 December 2020

Resistance, regulatory and production genes for the antibiotic methylenomycin are clustered

1 reference

12 December 2020

Isolation and partial characterisation of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus

1 reference

12 December 2020

Cloning and characterization of beta-lactam biosynthetic genes

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12 December 2020

The cloned Streptomyces bikiniensis A-factor determinant.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.38.636

Identifiers

DOI

10.1007/BF01569737

1 reference

7 August 2017

1 reference

PubMed ID

1368054