(Q35307950)

7 August 2017

title

Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain (English)

1 reference

7 August 2017

Chia-Chen Liu

1

1 reference

7 August 2017

Jin Hu

2

1 reference

7 August 2017

Chih-Wei Tsai

3

1 reference

7 August 2017

Mei Yue

4

1 reference

7 August 2017

Heather L Melrose

5

1 reference

7 August 2017

Takahisa Kanekiyo

6

1 reference

7 August 2017

Guojun Bu

7

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 April 2015

1 reference

7 August 2017

published in

Journal of Neuroscience

1 reference

7 August 2017

volume

35

1 reference

7 August 2017

issue

14

1 reference

7 August 2017

page(s)

5851-5859

1 reference

Low-density lipoprotein receptor-related protein 1 (LRP1) regulates the stability and function of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor in neurons

7 August 2017

cites work

1 reference

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12 July 2018

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12 July 2018

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12 July 2018

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LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype

12 July 2018

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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Alzheimer's disease is type 3 diabetes-evidence reviewed

12 July 2018

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Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling

12 July 2018

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12 July 2018

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12 July 2018

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Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents

12 July 2018

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12 July 2018

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12 July 2018

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Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

12 July 2018

1 reference

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12 July 2018

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Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine

12 July 2018

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12 July 2018

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Glucose metabolism and insulin receptor signal transduction in Alzheimer disease

12 July 2018

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Glucose transporter expression in the central nervous system: relationship to synaptic function

12 July 2018

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12 July 2018

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Brain insulin: regulation, mechanisms of action and functions

12 July 2018

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

12 July 2018

1 reference

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LRP: a multifunctional scavenger and signaling receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/positron-emission tomography (FDG/PET).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Cognitive effects of insulin in the central nervous system

12 July 2018

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Insulin promotes rapid delivery of N-methyl-D- aspartate receptors to the cell surface by exocytosis

12 July 2018

1 reference

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The insulin-stimulated cell surface presentation of low density lipoprotein receptor-related protein in 3T3-L1 adipocytes is sensitive to phosphatidylinositide 3-kinase inhibition.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

12 July 2018

1 reference

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Measurement of glucose uptake and intracellular calcium concentration in single, living pancreatic beta-cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

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12 July 2018

1 reference

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Subregion- and cell type-restricted gene knockout in mouse brain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein

12 July 2018

1 reference

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Morphological characterization of immortalized hypothalamic neurons synthesizing luteinizing hormone-releasing hormone

12 July 2018

1 reference

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Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases

12 July 2018

1 reference

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Downregulation of LRP1 [correction of LPR1] at the blood-brain barrier in streptozotocin-induced diabetic mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

What does fluorodeoxyglucose PET imaging add to a clinical diagnosis of dementia?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Insulin facilitates the hepatic clearance of plasma amyloid beta-peptide (1 40) by intracellular translocation of low-density lipoprotein receptor-related protein 1 (LRP-1) to the plasma membrane in hepatocytes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Kinetics of endothelin-induced inhibition and glucose permeability of astrocyte gap junctions

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

The effects of type 1 diabetes on cognitive performance: a meta-analysis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Glutamate mediates acute glucose transport inhibition in hippocampal neurons.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Increased risk of type 2 diabetes in Alzheimer disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388937

Intranasal insulin improves cognition and modulates beta-amyloid in early AD

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25855193

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

2013 Alzheimer's disease facts and figures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25855193

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.5180-14.2015

1 reference

7 August 2017

1 reference

7 August 2017

1 reference