(Q35310967)

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Intradomain cleavage of inhibitory prodomain is essential to protumorigenic function of membrane type-1 matrix metalloproteinase (MT1-MMP) in vivo.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Intradomain cleavage of inhibitory prodomain is essential to protumorigenic function of membrane type-1 matrix metalloproteinase (MT1-MMP) in vivo (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

author name string

Vladislav S Golubkov

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Andrei V Chernov

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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8 August 2011

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Europe PubMed Central

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10 February 2020

Journal of Biological Chemistry

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

286

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

39

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

34215-34223

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Localizing matrix metalloproteinase activities in the pericellular environment

1 reference

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1 reference

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1 reference

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27 July 2018

Internal cleavages of the autoinhibitory prodomain are required for membrane type 1 matrix metalloproteinase activation, although furin cleavage alone generates inactive proteinase.

1 reference

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Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1.

1 reference

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Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy

1 reference

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Proteolytic interstitial cell migration: a five-step process.

1 reference

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Breaching the basement membrane: who, when and how?

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The activation and physiological functions of the proprotein convertases

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MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer

1 reference

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27 July 2018

Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism

1 reference

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27 July 2018

Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cells

1 reference

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27 July 2018

Mouse models of breast cancer metastasis

1 reference

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27 July 2018

O-glycosylation regulates autolysis of cellular membrane type-1 matrix metalloproteinase (MT1-MMP).

1 reference

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27 July 2018

Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells.

1 reference

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27 July 2018

Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion

1 reference

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

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A monomeric red fluorescent protein

1 reference

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New functions for the matrix metalloproteinases in cancer progression

1 reference

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27 July 2018

Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation.

1 reference

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27 July 2018

Matrix metalloproteinases

1 reference

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Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity

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A matrix metalloproteinase expressed on the surface of invasive tumour cells

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Furin-dependent intracellular activation of the human stromelysin-3 zymogen

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Structure and function of matrix metalloproteinases and TIMPs

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Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix.

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Proteolysis of the membrane type-1 matrix metalloproteinase prodomain: implications for a two-step proteolytic processing and activation.

1 reference

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Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in brea

1 reference

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MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells

1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Lung metastasis fails in MMTV-PyMT oncomice lacking S100A4 due to a T-cell deficiency in primary tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21832072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.264036

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832072%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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