Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35311960)
Watch
English
Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
title
Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author
Nathaniel Sears
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author name string
Ganes C Sen
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
George R Stark
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Saurabh Chattopadhyay
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
language of work or name
English
0 references
publication date
4 August 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
volume
286
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
issue
38
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
page(s)
33037-33044
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
cites work
RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Phosphatidylinositol 3-kinase signaling delays sendai virus-induced apoptosis by preventing XIAP degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
The IRF-3/Bax-mediated apoptotic pathway, activated by viral cytoplasmic RNA and DNA, inhibits virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
The ubiquitin E3 ligase RAUL negatively regulates type i interferon through ubiquitination of the transcription factors IRF7 and IRF3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Viral apoptosis is induced by IRF-3-mediated activation of Bax
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Viral interferon regulatory factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
The role of differential expression of human interferon--a genes in antiviral immunity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
IPS-1 is crucial for DAP3-mediated anoikis induction by caspase-8 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Identification of Caspase-mediated Decay of Interferon Regulatory Factor-3, Exploited by a Kaposi Sarcoma-associated Herpesvirus Immunoregulatory Protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Nonproteolytic functions of ubiquitin in cell signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
S-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
IRF-3 activation by Sendai virus infection is required for cellular apoptosis and avoidance of persistence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
ImageJ for microscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Caspase-8-mediated apoptosis in human RPE cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
SVM-based prediction of caspase substrate cleavage sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 and, consequently, inhibits beta interferon promoter activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Essential role of IPS-1 in innate immune responses against RNA viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kappaB, and interferon but not toll-like receptor 3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Virus interference. I. The interferon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
A mutant cell line defective in response to double-stranded RNA and in regulating basal expression of interferon-stimulated genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
ARPE-19, a human retinal pigment epithelial cell line with differentiated properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
Characterization of a newly derived human sarcoma cell line (HT-1080).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190878
retrieved
12 July 2018
The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M111.257022
retrieved
21 January 2018
CASVM: web server for SVM-based prediction of caspase substrates cleavage sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M111.257022
retrieved
21 January 2018
Identifiers
DOI
10.1074/JBC.M111.257022
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PMC publication ID
3190878
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PubMed publication ID
21816816
1 reference
stated in
Europe PubMed Central
PMC publication ID
3190878
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21816816%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit