(Q35374753)

8 August 2017

title

Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth (English)

1 reference

8 August 2017

1 reference

Galina Gritsina

1

1 reference

8 August 2017

Fang Xiao

2

1 reference

8 August 2017

Shane W O'Brien

3

1 reference

8 August 2017

Rashid Gabbasov

4

1 reference

8 August 2017

Marisa A Maglaty

5

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8 August 2017

Ren-Huan Xu

6

1 reference

8 August 2017

Roshan J Thapa

7

1 reference

8 August 2017

Yan Zhou

8

1 reference

8 August 2017

Emmanuelle Nicolas

9

1 reference

8 August 2017

Samuel Litwin

10

1 reference

8 August 2017

Siddharth Balachandran

11

1 reference

8 August 2017

Luis J Sigal

12

1 reference

8 August 2017

Dennis Huszar

13

1 reference

8 August 2017

Denise C Connolly

14

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8 August 2017

publication date

2 February 2015

1 reference

Molecular Cancer Therapeutics

8 August 2017

published in

1 reference

8 August 2017

volume

14

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8 August 2017

issue

4

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8 August 2017

page(s)

1035-1047

1 reference

describes a project that uses

8 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4394029

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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27 July 2018

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Pharmacologic suppression of JAK1/2 by JAK1/2 inhibitor AZD1480 potently inhibits IL-6-induced experimental prostate cancer metastases formation

27 July 2018

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27 July 2018

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27 July 2018

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Network analysis identifies an HSP90-central hub susceptible in ovarian cancer

27 July 2018

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The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis

27 July 2018

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Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion

27 July 2018

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Combined in vivo molecular and anatomic imaging for detection of ovarian carcinoma-associated protease activity and integrin expression in mice

27 July 2018

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First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

27 July 2018

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27 July 2018

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Leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2

27 July 2018

1 reference

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Rethinking ovarian cancer: recommendations for improving outcomes

27 July 2018

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Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480.

27 July 2018

1 reference

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Integrated genomic analyses of ovarian carcinoma

27 July 2018

1 reference

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NF-kappaB protects cells from gamma interferon-induced RIP1-dependent necroptosis.

27 July 2018

1 reference

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The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors

27 July 2018

1 reference

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STATs in cancer inflammation and immunity: a leading role for STAT3

27 July 2018

1 reference

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In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Tumor-selective response to antibody-mediated targeting of alphavbeta3 integrin in ovarian cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Mechanisms of transcoelomic metastasis in ovarian cancer.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Touched and moved by STAT3.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Stat3 is required for full neoplastic transformation by the Simian Virus 40 large tumor antigen

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Stat3 regulates genes common to both wound healing and cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

ADAM15 decreases integrin alphavbeta3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Transmigration of human ovarian adenocarcinoma cells through endothelial extracellular matrix involves alphav integrins and the participation of MMP2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Bioconductor: open software development for computational biology and bioinformatics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Coexpression of oncostatin M and its receptors and evidence for STAT3 activation in human ovarian carcinomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

IL-6 production in ovarian carcinoma is associated with histiotype and biological characteristics of the tumour and influences local immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Minimum information necessary for quantitative real-time PCR experiments.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Xenograft and Transgenic Mouse Models of Epithelial Ovarian Cancer and Non Invasive Imaging Modalities to Monitor Ovarian Tumor Growth In situ -Applications in Evaluating Novel Therapeutic Agents.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Magnetic resonance imaging for detection and determination of tumor volume in a genetically engineered mouse model of ovarian cancer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Constitutive activation of stat 3 oncogene product in human ovarian carcinoma cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Roles of STAT3 defined by tissue-specific gene targeting

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394029

Targeting STAT3 in cancer: how successful are we?

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25646015

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Xenograft and transgenic mouse models of epithelial ovarian cancer and non-invasive imaging modalities to monitor ovarian tumor growth in situ: applications in evaluating novel therapeutic agents

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25646015

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1535-7163.MCT-14-0800

1 reference

8 August 2017

1 reference

8 August 2017

1 reference