(Q35402092)

8 August 2017

title

Dominant-negative mechanism of leukemogenic PAX5 fusions (English)

1 reference

8 August 2017

N Kawamata

1

1 reference

8 August 2017

M A Pennella

2

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8 August 2017

J L Woo

3

1 reference

8 August 2017

A J Berk

4

1 reference

8 August 2017

H P Koeffler

5

1 reference

8 August 2017

language of work or name

English

0 references

publication date

18 July 2011

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8 August 2017

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8 August 2017

volume

31

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8 August 2017

issue

8

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8 August 2017

page(s)

966-977

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The reduced and altered activities of PAX5 are linked to the protein-protein interaction motif (coiled-coil domain) of the PAX5-PML fusion protein in t(9;15)-associated acute lymphocytic leukemia

8 August 2017

cites work

1 reference

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12 July 2018

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12 July 2018

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Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray

12 July 2018

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Coiled-coil domain of PML is essential for the aberrant dynamics of PML-RARalpha, resulting in sequestration and decreased mobility of SMRT.

12 July 2018

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Transcriptional dysregulation during myeloid transformation in AML.

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12 July 2018

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Pax5: the guardian of B cell identity and function

12 July 2018

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12 July 2018

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Targeting the oligomerization domain of ETO interferes with RUNX1/ETO oncogenic activity in t(8;21)-positive leukemic cells

12 July 2018

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Dimerization-induced corepressor binding and relaxed DNA-binding specificity are critical for PML/RARA-induced immortalization

12 July 2018

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Decreased intranuclear mobility of acute myeloid leukemia 1-containing fusion proteins is accompanied by reduced mobility and compartmentalization of core binding factor beta

12 July 2018

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REPPER--repeats and their periodicities in fibrous proteins

12 July 2018

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FRAP analysis of binding: proper and fitting

12 July 2018

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Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins

12 July 2018

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Dimerization: a versatile switch for oncogenesis

12 July 2018

1 reference

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Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha

12 July 2018

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PML-RARA-RXR oligomers mediate retinoid and rexinoid/cAMP cross-talk in acute promyelocytic leukemia cell differentiation

12 July 2018

1 reference

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Measurement of molecular interactions in living cells by fluorescence resonance energy transfer between variants of the green fluorescent protein

12 July 2018

1 reference

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Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

Role of the histone deacetylase complex in acute promyelocytic leukaemia

12 July 2018

1 reference

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C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8.

12 July 2018

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DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

12 July 2018

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Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

12 July 2018

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Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations

12 July 2018

1 reference

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Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations.

12 July 2018

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Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

A novel PAX5-ELN fusion protein identified in B-cell acute lymphoblastic leukemia acts as a dominant negative on wild-type PAX5.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

Paircoil2: improved prediction of coiled coils from sequence.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

Purified promyelocytic leukemia coiled-coil aggregates as a tetramer displaying low α-helical content

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

An HMM model for coiled-coil domains and a comparison with PSSM-based predictions.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3197879

CtBP, an unconventional transcriptional corepressor in development and oncogenesis

26 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.291

Structure and functionality of a designed p53 dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.291

Characterization of mediator complexes from HeLa cell nuclear extract

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.291

PAX5/TEL acts as a transcriptional repressor causing down-modulation of CD19, enhances migration to CXCL12, and confers survival advantage in pre-BI cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.291

Environmental-dependent acceleration of a developmental switch: the floral transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.291

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.291

1 reference

8 August 2017

1 reference

8 August 2017

1 reference