(Q35435068)

English

Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

8 August 2017

Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1. (English)

1 reference

Europe PubMed Central

8 August 2017

0 references

author name string

Nobuhiro Kamiya

1

1 reference

Europe PubMed Central

8 August 2017

Vesa M Kaartinen

2

1 reference

Europe PubMed Central

8 August 2017

Yuji Mishina

3

1 reference

Europe PubMed Central

8 August 2017

language of work or name

0 references

publication date

17 September 2011

1 reference

Europe PubMed Central

8 August 2017

Biochemical and Biophysical Research Communications

1 reference

Europe PubMed Central

8 August 2017

414

1 reference

Europe PubMed Central

8 August 2017

2

1 reference

Europe PubMed Central

8 August 2017

326-330

1 reference

Europe PubMed Central

8 August 2017

Osteoporosis: now and the future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Conversion of vascular endothelial cells into multipotent stem-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Bone morphogenetic protein (BMP) for fracture healing in adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Identification of progenitor cells that contribute to heterotopic skeletogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Fibrodysplasia ossificans progressiva

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

A novel transgenic mouse model to study the osteoblast lineage in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Clinical applications of BMP-7/OP-1 in fractures, nonunions and spinal fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Wnt signaling: a key regulator of bone mass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Regulation of bone mass by Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Bone morphogenetic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

TGF-beta signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Bone: formation by autoinduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

Receptors for the TGF-β family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

27 July 2018

New insights on the roles of BMP signaling in bone-A review of recent mouse genetic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

26 September 2018

rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

26 September 2018

Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

26 September 2018

BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

26 September 2018

Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

26 September 2018

Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

26 September 2018

Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

26 September 2018

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200475

26 September 2018

Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21945937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/21945937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development

1 reference

https://pubmed.ncbi.nlm.nih.gov/21945937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of OP-1 in femoral impaction grafting in a sheep model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21945937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBRC.2011.09.060

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q35435068&oldid=1982190105"