(Q35445369)

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Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

0 references

cilium assembly

0 references

Si:ch211-185a18.2

1 reference

GOA release 2020-03-11

Philip W Ingham

5

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

author name string

Jin Ben

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Stone Elworthy

2

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Ashley Shu Mei Ng

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Freek van Eeden

4

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

language of work or name

0 references

publication date

1 November 2011

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

138

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

4969-4978

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Generation of mice with functional inactivation of talpid3, a gene first identified in chicken

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Mechanisms and functions of Hedgehog signalling across the metazoa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

The iguana/DZIP1 protein is a novel component of the ciliogenic pathway essential for axonemal biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

The Zn finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect hedgehog signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Genetic steps to organ laterality in zebrafish.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Unexpected failure rates for modular assembly of engineered zinc fingers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Controlling morpholino experiments: don't stop making antisense.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Genetic analysis of the two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Cilia and developmental signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Orchestrating ontogenesis: variations on a theme by sonic hedgehog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Nodal flow and the generation of left-right asymmetry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Production of maternal-zygotic mutant zebrafish by germ-line replacement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

In vivo imaging of embryonic vascular development using transgenic zebrafish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Gli1 can rescue the in vivo function of Gli2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

A zebrafish nanos-related gene is essential for the development of primordial germ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Large scale genetics in a small vertebrate, the zebrafish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

A scanning electron microscope study of the early limb-bud in normal and talpid3 mutant chick embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Localization of delta-crystallin RNA during lens morphogenesis and differentiation in the normal and talpid3 chick embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

12 July 2018

Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

Combined activity of the two Gli2 genes of zebrafish play a major role in Hedgehog signaling during zebrafish neurodevelopment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

DEVELOPMENTAL ABNORMALITIES IN THE TRUNK AND LIMBS OF THE TALPID3 MUTANT OF THE FOWL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

Regulation of left-right asymmetries in the zebrafish by Shh and BMP4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

Expression of ptc and gli genes in talpid3 suggests bifurcation in Shh pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201664

26 September 2018

A molecular pathway determining left-right asymmetry in chick embryogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22028029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic inhibition of mesenchymal cell death and the development of form and skeletal pattern in the limbs of talpid3 (ta3) mutant chick embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/22028029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The capacity of normal and talpid3 mutant fowl myogenic cells to migrate in quail limb buds

1 reference

https://pubmed.ncbi.nlm.nih.gov/22028029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1242/DEV.070862

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

0 references

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