Wikidata

(Q3547204)

English

UDP glucuronosyltransferase family 1 member A1

mammalian protein found in Homo sapiens

  • UGT1A1
  • bilirubin UDP-glucuronosyltranserase
  • UDP-glucuronosyltransferase 1A1
  • bilirubin UDP-glucuronosyltransferase 1-1
  • UDP-glucuronosyltransferase 1-1
  • UDP-glucuronosyltransferase 1-A
  • bilirubin-specific UDPGT isozyme 1
  • hUG-BR1
  • UGT1.1
  • UGT-1A
  • bilirubin UDP-glucuronosyltransferase isozyme 1
  • UGT1-01
  • UDP glycosyltransferase 1 family, polypeptide A1
  • UGT1*1
  • UDP glucuronosyltransferase 1 family, polypeptide A1
  • UGT1A
In more languages

Statements

molecular function
glucuronosyltransferase activity
determination method
IEA
IDA
ISS
TAS
IKR
12 references
retrieved
27 February 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
TAS
retrieved
27 February 2018
stated in
Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
ISS
retrieved
27 February 2018
stated in
Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IKR
retrieved
27 February 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IEA
retrieved
27 February 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IEA
retrieved
27 February 2018
stated in
Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
27 February 2018
stated in
Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
27 February 2018
stated in
Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
27 February 2018
stated in
Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
27 February 2018
stated in
Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
27 February 2018
stated in
Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
27 February 2018
stated in
Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
glucuronosyltransferase activity
determination method
IDA
IEA
TAS
10 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
TAS
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IEA
retrieved
1 January 2018
stated in
Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
1 January 2018
stated in
Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
1 January 2018
stated in
Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
1 January 2018
stated in
Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
1 January 2018
stated in
Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
1 January 2018
stated in
Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
1 January 2018
stated in
Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
glucuronosyltransferase activity
determination method
IDA
IEA
9 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IEA
retrieved
8 April 2019
stated in
Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
8 April 2019
stated in
Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
8 April 2019
stated in
Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
8 April 2019
stated in
Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
8 April 2019
stated in
Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
8 April 2019
stated in
Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
8 April 2019
stated in
Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22309
determination method
IDA
cell component
biological process
cellular glucuronidation
determination method
IEA
IDA
ISS
TAS
5 references
retrieved
27 February 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
TAS
retrieved
27 February 2018
stated in
Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
ISS
retrieved
27 February 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IEA
retrieved
27 February 2018
stated in
Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA
retrieved
27 February 2018
stated in
Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation
GOA
curator
UniProt
UniProt protein ID
P22309
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22309&geneProductId=UniProtKB:P22309
determination method
IDA

Identifiers

 
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