(Q35489132)

8 August 2017

1 reference

title

Perforin and its role in T lymphocyte-mediated cytolysis (English)

1 reference

8 August 2017

main subject

immunologic cytotoxicity

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1426142

25 September 2022

author name string

B. Lowin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1426142

25 September 2022

O. Krähenbühl

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1426142

25 September 2022

C. Müller

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1426142

25 September 2022

M. Dupuis

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1426142

25 September 2022

J. Tschopp

5

1 reference

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25 September 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1426142

25 September 2022

publication date

1 October 1992

1 reference

8 August 2017

15 October 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1426142

25 September 2022

1 reference

8 August 2017

volume

48

1 reference

8 August 2017

issue

10

1 reference

8 August 2017

page(s)

911-920

1 reference

The role of cytoplasmic granules in lymphocyte cytotoxicity

8 August 2017

cites work

1 reference

12 December 2020

Internal Disintegration Model of Cytotoxic Lymphocyte-Induced Target Damage

1 reference

12 December 2020

Selective lysis of NK-sensitive target cells by a soluble mediator released from murine spleen cells and human peripheral blood lymphocytes

1 reference

12 December 2020

Early steps in specific tumor cell lysis by sensitized mouse T lymphocytes. II. Electrolyte permeability increase in the target cell membrane concomitant with programming for lysis

1 reference

12 December 2020

Mechanism of lysis by large granular lymphocyte granule cytolysin: generation of a stable cytolysin-RBC intermediate

1 reference

12 December 2020

Cell death: the significance of apoptosis

1 reference

12 December 2020

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death

1 reference

12 December 2020

Identification and characterization of a pore-forming protein of human peripheral blood natural killer cells

1 reference

12 December 2020

Killing of target cells by lymphocytes: a mechanistic view

1 reference

12 December 2020

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

1 reference

12 December 2020

Dissociation of membrane binding and lytic activities of the lymphocyte pore-forming protein (perforin).

1 reference

12 December 2020

Inhibition of lymphocyte mediated cytotoxicity by perforin antisense oligonucleotides

1 reference

12 December 2020

Cloning and expression of murine lymphotoxin cDNA.

1 reference

12 December 2020

Liposomes as targets for granule cytolysin from cytotoxic large granular lymphocyte tumors

1 reference

12 December 2020

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs

1 reference

12 December 2020

Appearance of cytolytic granules upon induction of cytolytic activity in CTL-hybrids

1 reference

12 December 2020

The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities

1 reference

12 December 2020

Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells

1 reference

12 December 2020

Localization and molecular modelling of the membrane-inserted domain of the ninth component of human complement and perforin

1 reference

12 December 2020

Permeability changes induced in erthrocyte ghost targets by antibody-dependent cytotoxic effector cells: evidence for membrane pores

1 reference

12 December 2020

Electron microscopic demonstration of lesions in target cell membranes associated with antibody-dependent cellular cytotoxicity

1 reference

12 December 2020

Tumor immunity in vitro: destruction of a mouse ascites tumor through a cycling pathway

1 reference

12 December 2020

Phosphorylcholine acts as a Ca2+-dependent receptor molecule for lymphocyte perforin

1 reference

12 December 2020

Mechanism of lymphocyte-mediated cytotoxicity

1 reference

12 December 2020

Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes

1 reference

12 December 2020

Establishment in culture of pluripotential cells from mouse embryos

1 reference

12 December 2020

1 reference

12 December 2020

A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells

1 reference

12 December 2020

Mechanism of cytotoxicity of human large granular lymphocytes: relationship of the cytotoxic lymphocyte protein to the ninth component (C9) of human complement

1 reference

12 December 2020

Formation of transmembrane tubules by spontaneous polymerization of the hydrophilic complement protein C9

1 reference

12 December 2020

T-cell antigen receptor genes and T-cell recognition

1 reference

12 December 2020

Perforin-mediated myocardial damage in acute myocarditis

1 reference

12 December 2020

A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/perforin gene

1 reference

12 December 2020

Cytolytic and biochemical properties of cytoplasmic granules of murine lymphokine-activated killer cells

1 reference

12 December 2020

Appearance of granule-associated molecules during activation of cytolytic T-lymphocyte precursors by defined stimuli

1 reference

12 December 2020

Identification, isolation, and characterization of a novel cytotoxin in murine cytolytic lymphocytes

1 reference

12 December 2020

Mechanisms of immune lysis. II. CTL-induced nuclear disintegration of the target begins within minutes of cell contact

1 reference

12 December 2020

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

1 reference

12 December 2020

Homology of perforin to the ninth component of complement (C9).

1 reference

12 December 2020

Mechanistic, functional and immunopharmacological implications of biochemical studies of antigen receptor-triggered cytolytic T-lymphocyte activation

1 reference

12 December 2020

Neoantigen of the complement membrane attack complex of cytotoxic human peripheral blood lymphocytes

1 reference

12 December 2020

Functional channel formation associated with cytotoxic T-cell granules

1 reference

12 December 2020

Membrane attack by complement

1 reference

12 December 2020

Cytotoxic granules from killer cells: specificity of granules and insertion of channels of defined size into target membranes

1 reference

12 December 2020

Cytolytic activity of purified cytoplasmic granules from cytotoxic rat large granular lymphocyte tumors

1 reference

12 December 2020

Transients of perforin pore formation observed by fluorescence microscopic single channel recording

1 reference

12 December 2020

The reorientation of the Golgi apparatus and the microtubule-organizing center in the cytotoxic effector cell is a prerequisite in the lysis of bound target cells

1 reference

12 December 2020

Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells

1 reference

12 December 2020

Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A.

1 reference

12 December 2020

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

1 reference

12 December 2020

Mechanisms of immune lysis. III. Characterization of the nature and kinetics of the cytotoxic T lymphocyte-induced nuclear lesion in the target

1 reference

12 December 2020

Programmed death of autoreactive thymocytes.

1 reference

12 December 2020

Estimation of the size of a T-cell-induced lytic lesion

1 reference

12 December 2020

Perforin-mediated target cell lysis by cytolytic T lymphocytes

1 reference

12 December 2020

Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization

1 reference

12 December 2020

Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography

1 reference

12 December 2020

Molecules relevant for T cell-target cell interaction are present in cytolytic granules of human T lymphocytes

1 reference

12 December 2020

Molecular cloning of rat cytolysin

1 reference

12 December 2020

Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro

1 reference

12 December 2020

Characterization of granzymes A and B isolated from granules of cloned human cytotoxic T lymphocytes

1 reference

12 December 2020

Ultrastructural alteration of cytolytic T lymphocytes following their interaction with target cells. II. Morphogenesis of secretory granules and intracellular vacuoles

1 reference

12 December 2020

Cytolysis by H-2-specific T killer cells. Assembly of tubular complexes on target membranes

1 reference

12 December 2020

Molecular mechanisms of cytolysis by complement and by cytolytic lymphocytes

1 reference

12 December 2020

Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules

1 reference

12 December 2020

Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis

1 reference

12 December 2020

Properties of a purified pore-forming protein (perforin 1) isolated from H-2-restricted cytotoxic T cell granules

1 reference

12 December 2020

Molecular mechanisms of cytotoxicity: comparison of complement and killer lymphocytes

1 reference

12 December 2020

Structure and function of human perforin

1 reference

12 December 2020

The sequence and topology of human complement component C9

1 reference

12 December 2020

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1 reference

12 December 2020

The cytolytic protein of human lymphocytes related to the ninth component (C9) of human complement: isolation from anti-CD3-activated peripheral blood mononuclear cells

1 reference

12 December 2020

Cellular and humoral mechanisms of cytotoxicity: structural and functional analogies

1 reference

12 December 2020

Adhesion receptors of the immune system

1 reference

12 December 2020

Molecular cloning and chromosomal assignment of a human perforin (PFP) gene

1 reference

12 December 2020

Structural/functional similarity between proteins involved in complement- and cytotoxic T-lymphocyte-mediated cytolysis

1 reference

12 December 2020

Mechanisms of immune lysis. I. Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement

1 reference

12 December 2020

Damage to mammalian cells by proteins that form transmembrane pores

1 reference

12 December 2020

The activation of resting lymphocytes is accompanied by the biogenesis of lysosomal organelles

1 reference

12 December 2020

Characterization of soluble factors that induce the cytolytic activity and the expression of T cell growth factor receptors of a T cell hybrid

1 reference

12 December 2020

Lymphocyte mediated cytolysis as a secretory phenomenon

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01919138

1 reference

8 August 2017

1 reference