(Q35515744)

English

Estrogen-related receptor γ (ERRγ) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling

scientific article published on 12 September 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Estrogen-related receptor γ (ERRγ) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

author name string

Don-Kyu Kim

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Jung Ran Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Minseob Koh

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Yong Deuk Kim

4

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Ji-Min Lee

5

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Dipanjan Chanda

6

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Seung Bum Park

7

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Jung-Joon Min

8

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Chul-Ho Lee

9

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Tae-Sik Park

10

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Hueng-Sik Choi

11

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

language of work or name

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publication date

12 September 2011

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

286

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

44

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

38035-38042

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Sterol-mediated regulation of human lipin 1 gene expression in hepatoblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

The orphan nuclear receptor estrogen receptor-related receptor gamma negatively regulates BMP2-induced osteoblast differentiation and bone formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Orphan nuclear receptor SHP interacts with and represses hepatocyte nuclear factor-6 (HNF-6) transactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

The orphan nuclear receptor, NOR-1, a target of beta-adrenergic signaling, regulates gene expression that controls oxidative metabolism in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

The cellular functions of the yeast lipin homolog PAH1p are dependent on its phosphatidate phosphatase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Structure and function of the atypical orphan nuclear receptor small heterodimer partner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Disordered lipid metabolism and the pathogenesis of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Nuclear receptor expression links the circadian clock to metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Lipin, a lipodystrophy and obesity gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Estrogen receptor-related receptor gamma has an exceptionally broad specificity of DNA sequence recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Evidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

PGC-1 and PERC, coactivators of the estrogen receptor-related receptor gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Adipose tissue deficiency, glucose intolerance, and increased atherosclerosis result from mutation in the mouse fatty liver dystrophy (fld) gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

12 July 2018

TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250613

21 January 2018

Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250613

21 January 2018

ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250613

21 January 2018

Differential role of the loop region between helices H6 and H7 within the orphan nuclear receptors small heterodimer partner and DAX-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250613

21 January 2018

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250613

21 January 2018

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250613

21 January 2018

Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.250613

21 January 2018

Determination of the molecular species composition of diacylglycerols in human adipose tissue by solid-phase extraction and gas chromatography on a polar phase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207427

26 September 2018

Deoxyribonucleic acid response element-dependent regulation of transcription by orphan nuclear receptor estrogen receptor-related receptor gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21911493

12 December 2020

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Identifiers

10.1074/JBC.M111.250613

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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