(Q35524598)

8 August 2017

title

The role of Notch signaling in muscle progenitor cell depletion and the rapid onset of histopathology in muscular dystrophy (English)

1 reference

8 August 2017

Xiaodong Mu

1

1 reference

8 August 2017

Ying Tang

2

1 reference

8 August 2017

Aiping Lu

3

1 reference

8 August 2017

Koji Takayama

4

1 reference

8 August 2017

Arvydas Usas

5

1 reference

8 August 2017

Bing Wang

6

1 reference

8 August 2017

Kurt Weiss

7

1 reference

8 August 2017

Johnny Huard

8

1 reference

8 August 2017

publication date

12 February 2015

1 reference

8 August 2017

published in

Human Molecular Genetics

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8 August 2017

volume

24

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8 August 2017

issue

10

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8 August 2017

page(s)

2923-2937

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A Wnt-TGFβ2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice

8 August 2017

cites work

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RhoA mediates defective stem cell function and heterotopic ossification in dystrophic muscle of mice

27 July 2018

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Impact of notch signaling on inflammatory responses in cardiovascular disorders

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The ubiquitin ligase Nedd4-1 participates in denervation-induced skeletal muscle atrophy in mice

27 July 2018

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Notch activation induces endothelial cell senescence and pro-inflammatory response: implication of Notch signaling in atherosclerosis

27 July 2018

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IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

27 July 2018

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Hypoxia promotes satellite cell self-renewal and enhances the efficiency of myoblast transplantation

27 July 2018

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Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

27 July 2018

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Constitutive Notch activation upregulates Pax7 and promotes the self-renewal of skeletal muscle satellite cells

27 July 2018

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Notch inhibition as a promising new approach to cancer therapy

27 July 2018

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Notch signaling mediates TGF-β1-induced epithelial-mesenchymal transition through the induction of Snai1.

27 July 2018

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NF-κB negatively impacts the myogenic potential of muscle-derived stem cells

27 July 2018

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27 July 2018

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A critical requirement for notch signaling in maintenance of the quiescent skeletal muscle stem cell state

27 July 2018

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Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice

27 July 2018

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Notch signaling is necessary to maintain quiescence in adult muscle stem cells

27 July 2018

1 reference

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Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers.

27 July 2018

1 reference

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Notch induces myofibroblast differentiation of alveolar epithelial cells via transforming growth factor-{beta}-Smad3 pathway

27 July 2018

1 reference

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Stem cells for skeletal muscle repair

27 July 2018

1 reference

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Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.

27 July 2018

1 reference

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Epigenetic regulation of satellite cell activation during muscle regeneration.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Human myostatin negatively regulates human myoblast growth and differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Targeting the jagged/notch pathway: a new treatment for fibrosis?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch signaling in cardiovascular disease and calcification.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

The Notch effector Hey1 associates with myogenic target genes to repress myogenesis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Ectopic calcification is caused by elevated levels of serum inorganic phosphate in mdx mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch signaling enhances osteogenic differentiation while inhibiting adipogenesis in primary human bone marrow stromal cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch signaling contributes to the pathogenesis of human osteosarcomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Inhibition of myogenesis by Notch: evidence for multiple pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Osteogenic potential of postnatal skeletal muscle-derived stem cells is influenced by donor sex.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin-dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Delta-like 4 induces notch signaling in macrophages: implications for inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Stra13 regulates satellite cell activation by antagonizing Notch signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch signaling, gamma-secretase inhibitors, and cancer therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch signaling in stem cell systems

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Isolation and culture of skeletal muscle myofibers as a means to analyze satellite cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Differentiation of muscle-derived cells into myofibroblasts in injured skeletal muscle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

TNF inhibits myogenesis and downregulates the expression of myogenic regulatory factors myoD and myogenin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

X chromosome-linked muscular dystrophy (mdx) in the mouse

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

The regeneration of skeletal muscle. A review

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch1-mediated signaling regulates proliferation of porcine satellite cells (PSCs).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Inhibition of Notch signaling by a γ-secretase inhibitor attenuates hepatic fibrosis in rats

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

[Notch pathway: from development to regeneration of skeletal muscle].

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

New role of Notch-mediated signaling pathway in myocardial ischemic preconditioning

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Dlk1 is necessary for proper skeletal muscle development and regeneration

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Blockade of Notch1 signaling alleviates murine lupus via blunting macrophage activation and M2b polarization.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Notch signaling induces osteogenic differentiation and mineralization of vascular smooth muscle cells: role of Msx2 gene induction via Notch-RBP-Jk signaling

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

TNF induction of jagged-1 in endothelial cells is NFkappaB-dependent

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

C Histomorphology of neuromuscular junction in Duchenne muscular dystrophy.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Ectopic mineralization of connective tissue in Abcc6-/- mice: effects of dietary modifications and a phosphate binder--a preliminary study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Targeting Notch signaling in autoimmune and lymphoproliferative disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Impaired expression of Notch signaling genes in aged human skeletal muscle.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Antifibrotic effects of suramin in injured skeletal muscle after laceration

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406301

Newly identified essential amino acid residues affecting Δ8-sphingolipid desaturase activity revealed by site-directed mutagenesis.

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDV055

Gene expression profiling in the early phases of DMD: a constant molecular signature characterizes DMD muscle from early postnatal life throughout disease progression

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDV055

Off the beaten pathway: the complex cross talk between Notch and NF-kappaB

21 January 2018

1 reference

12 December 2020

Isolation of a slowly adhering cell fraction containing stem cells from murine skeletal muscle by the preplate technique

1 reference

12 December 2020

Cardiac dysfunction and pathology in the dystrophin and utrophin-deficient mouse during development of dilated cardiomyopathy

1 reference

12 December 2020

MyoD is required for myogenic stem cell function in adult skeletal muscle

1 reference

12 December 2020

Roles of the calcineurin and CaMK signaling pathways in fast-to-slow fiber type transformation of cultured adult mouse skeletal muscle fibers

1 reference

12 December 2020

Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice

1 reference

12 December 2020

Notch3 null mutation in mice causes muscle hyperplasia by repetitive muscle regeneration

1 reference

12 December 2020

Nandrolone reduces activation of Notch signaling in denervated muscle associated with increased Numb expression

1 reference

12 December 2020

[Relation of notch pathway to senescence of murine bone marrow stromal cells]

1 reference

12 December 2020

Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy

1 reference

12 December 2020

Three-dimensional porous scaffold allows long-term wild-type cell delivery in dystrophic muscle

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDV055

1 reference

8 August 2017

1 reference

8 August 2017

1 reference